دورية أكاديمية
أعرض في EDS

Lyme disease vaccine attitudes and intentions among parents of children aged 5-18 years in the United States.

التفاصيل البيبلوغرافية
العنوان: Lyme disease vaccine attitudes and intentions among parents of children aged 5-18 years in the United States.
المؤلفون: Gidengil C; RAND Corporation, 20 Park Plaza, Suite 910, Boston, MA 02116, USA. Electronic address: gidengil@rand.org., Scherer AM; University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA., Parker AM; RAND Corporation, 4570 Fifth Ave #600, Pittsburgh, PA 15213, USA., Gedlinske A; University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA., Fleck-Derderian S; Centers for Disease Control and Prevention, National Centers for Emerging and Zoonotic Infectious Diseases, Division of Vector-Borne Diseases, 3156 Rampart Road, Fort Collins, CO 80521, USA., Hinckley AF; Centers for Disease Control and Prevention, National Centers for Emerging and Zoonotic Infectious Diseases, Division of Vector-Borne Diseases, 3156 Rampart Road, Fort Collins, CO 80521, USA., Hook SA; Centers for Disease Control and Prevention, National Centers for Emerging and Zoonotic Infectious Diseases, Division of Vector-Borne Diseases, 3156 Rampart Road, Fort Collins, CO 80521, USA., Lindley MC; Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases, Immunization Services Division, 1600 Clifton Road, Atlanta, GA 30329, USA., Marx GE; Centers for Disease Control and Prevention, National Centers for Emerging and Zoonotic Infectious Diseases, Division of Vector-Borne Diseases, 3156 Rampart Road, Fort Collins, CO 80521, USA.
المصدر: Vaccine [Vaccine] 2024 Mar 19; Vol. 42 (8), pp. 1899-1905. Date of Electronic Publication: 2024 Feb 28.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 8406899 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2518 (Electronic) Linking ISSN: 0264410X NLM ISO Abbreviation: Vaccine Subsets: MEDLINE
أسماء مطبوعة: Publication: Amsterdam, The Netherlands : Elsevier Science
Original Publication: [Guildford, Surrey, UK] : Butterworths, [c1983-
مواضيع طبية MeSH: Vaccines* , Lyme Disease*/prevention & control, Child ; Humans ; United States ; Lyme Disease Vaccines ; Intention ; Health Knowledge, Attitudes, Practice ; Parents ; Antibodies, Monoclonal ; Vaccination
مستخلص: Background: Lyme disease (LD) is the most common vector-borne disease in the United States, with increasing incidence and geographic range. Case incidence peaks among school-aged children. New LD preventives are in clinical trials.
Methods: We conducted an online survey of parents of children aged 5-18 years in states with high or emerging incidence of LD. Our primary outcome was willingness ("definitely" or "probably") for their child to receive an LD vaccine. Our secondary outcome was preference for annual monoclonal antibody injections compared to a 3-dose vaccine series with boosters. Analyses were weighted to reflect parent gender, parent race/ethnicity, and child age by state.
Results: Among 1,351 parent respondents, most (68.0 %) would have their child vaccinated against LD, with significantly more being willing in high compared to emerging incidence states (70.4 % versus 63.6 %, p = 0.027). Of parents who were unsure or unwilling, 33.5 % and 16.5 %, respectively, would do so with a provider recommendation. Vaccine safety concerns were among the top reasons for LD vaccine hesitancy. More parents preferred a pre-formed antibody (42.3 %) compared to a 3-dose vaccine series (34.7 %). Significant predictors of willingness to have one's child vaccinated were higher parental education; higher perceived risk of child getting LD; child spending time outdoors daily or weekly; following a regular vaccine schedule; and positive attitude towards vaccines. Significant predictors of preference for monoclonal antibody over a 3-dose vaccine series included prior awareness of LD, living in a rural area, and less positive attitudes towards vaccines.
Conclusions: Two-thirds of parents in high and emerging incidence states would vaccinate their children against Lyme disease. Addressing safety concerns will be important, and a health care provider recommendation could also encourage those who are unsure or unwilling. Given the slight preference for monoclonal antibody over vaccine, particularly in rural areas, access to both may increase LD prevention.
Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Courtney Gidengil reports financial support was provided by Centers for Disease Control and Prevention. I have served as an ad hoc reviewer for manuscripts submitted to Vaccine in the past. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 RAND Corporation. Published by Elsevier Ltd.. All rights reserved.)
معلومات مُعتمدة: U01 IP001144 United States IP NCIRD CDC HHS
فهرسة مساهمة: Keywords: Children; Lyme disease; Monoclonal antibody; Vaccine; Vaccine attitudes; Vaccine intentions
المشرفين على المادة: 0 (Lyme Disease Vaccines)
0 (Vaccines)
0 (Antibodies, Monoclonal)
تواريخ الأحداث: Date Created: 20240228 Date Completed: 20240318 Latest Revision: 20240404
رمز التحديث: 20240404
DOI: 10.1016/j.vaccine.2024.01.081
PMID: 38418339
قاعدة البيانات: MEDLINE
الوصف
تدمد:1873-2518
DOI:10.1016/j.vaccine.2024.01.081