دورية أكاديمية
Aluminum potassium sulfate and tannic acid (ALTA) sclerotherapy for hemorrhoidal disease: a systematic review and meta-analysis.
| العنوان: | Aluminum potassium sulfate and tannic acid (ALTA) sclerotherapy for hemorrhoidal disease: a systematic review and meta-analysis. |
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| المؤلفون: | Manaki V; Department of Vascular Surgery, Aristotle University of Thessaloniki, AHEPA University General Hospital, Thessaloniki, Greece., Bontinis V; Department of Vascular Surgery, Aristotle University of Thessaloniki, AHEPA University General Hospital, Thessaloniki, Greece., Bontinis A; Department of Vascular Surgery, Aristotle University of Thessaloniki, AHEPA University General Hospital, Thessaloniki, Greece., Giannopoulos A; Department of Vascular Surgery, Aristotle University of Thessaloniki, AHEPA University General Hospital, Thessaloniki, Greece., Kontes I; Department of Vascular Surgery, Aristotle University of Thessaloniki, AHEPA University General Hospital, Thessaloniki, Greece., Chorti A; Department of Surgery, Aristotle University of Thessaloniki, AHEPA University General Hospital, Thessaloniki, Greece., Ktenidis K; Department of Vascular Surgery, Aristotle University of Thessaloniki, AHEPA University General Hospital, Thessaloniki, Greece. |
| المصدر: | Acta chirurgica Belgica [Acta Chir Belg] 2024 Aug; Vol. 124 (4), pp. 253-260. Date of Electronic Publication: 2024 Mar 08. |
| نوع المنشور: | Journal Article; Systematic Review; Meta-Analysis; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Taylor & Francis Country of Publication: England NLM ID: 0370571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0001-5458 (Print) Linking ISSN: 00015458 NLM ISO Abbreviation: Acta Chir Belg Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2016- : London : Taylor & Francis Original Publication: Bruxelles : Acta Medica Belgica |
| مواضيع طبية MeSH: | Hemorrhoids*/therapy , Sclerotherapy*/methods , Tannins*/therapeutic use , Alum Compounds*/therapeutic use , Sclerosing Solutions*/therapeutic use, Humans ; Treatment Outcome ; Recurrence ; Polyphenols |
| مستخلص: | Background: We conducted a systematic review to assess the safety and efficacy of Aluminum potassium sulfate and tannic acid (ALTA) sclerotherapy for the treatment of hemorrhoidal disease. Methods: Our study was conducted in accordance with the PRISMA statement (Preferred Reporting Items for Systematic Reviews and Meta-analyses) 2020. Primary endpoints included overall recurrence and type of recurrence while secondary endpoints included postoperative complications, reintervention, presence of rectal ulcer, rectal stricture, defecation abnormalities and perianal abscess. Α regression analysis, where the percentage of patients with grade II, III and IV hemorrhoidal disease was used as a covariate, was also performed. Results: Twelve studies with 4249 patients met all the inclusion criteria and were eventually included. The crude and pooled estimates of the overall recurrence and complications by the end of follow-up were 10% (95% CI, 6.52%-14.08%) and 5.20% (95% CI, 2.59%-8.52%), respectively. Regression analysis displayed no correlation between recurrence and the grade of hemorrhoid disease II, β= -0.0012 (95% CI, -0.0074 to 0.0049) ( p = .64), grade III β= -0.0006 (95% CI, -0.0056 to 0.0045) ( p = .79) and grade IV β = 0.0025 (95% CI, -0.0075 to 0.0124). However, a trend suggestive of increased recurrence was observed in patient populations with a higher proportion of grade IV disease. Conclusion: ALTA sclerotherapy may be a safe and viable alternative for patients with hemorrhoidal disease. Long-term follow-up and high-quality randomized controlled trials will help define the place of ALTA sclerotherapy in the armamentarium of treatment of hemorrhoids. |
| فهرسة مساهمة: | Keywords: ALTA; aluminum potassium sulfate; hemorrhoidal disease; hemorrhoids; sclerotherapy |
| المشرفين على المادة: | 0 (Tannins) 0 (Alum Compounds) 34S289N54E (aluminum sulfate) 0 (Sclerosing Solutions) 0 (tannic acid) 0 (Polyphenols) |
| تواريخ الأحداث: | Date Created: 20240301 Date Completed: 20240724 Latest Revision: 20240725 |
| رمز التحديث: | 20240726 |
| DOI: | 10.1080/00015458.2024.2326273 |
| PMID: | 38428446 |
| قاعدة البيانات: | MEDLINE |
PDF full text from Publisher | تدمد: | 0001-5458 |
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| DOI: | 10.1080/00015458.2024.2326273 |