دورية أكاديمية
Follow-up echocardiographic changes in children and youth aged <25 years with latent rheumatic heart disease: A systematic review and meta-analysis of global data.
| العنوان: | Follow-up echocardiographic changes in children and youth aged <25 years with latent rheumatic heart disease: A systematic review and meta-analysis of global data. |
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| المؤلفون: | Francia CJ; School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Queensland, Australia; The Poche Centre for Indigenous Health, The University of Queensland, Brisbane, Queensland, Australia. Electronic address: c.francia@uq.edu.au., Fraser JF; The Critical Care Research Group, The Prince Charles Hospital, Chermside, Queensland, Australia; Faculty of Medicine, University of Queensland, Brisbane, Queensland, Australia., Justo R; Faculty of Medicine, University of Queensland, Brisbane, Queensland, Australia., Cassimatis J; The Critical Care Research Group, The Prince Charles Hospital, Chermside, Queensland, Australia; Medical Program, Bond University, Gold Coast, Queensland, Australia., Manoy S; College of Medicine and Dentistry, James Cook University, Cairns, Queensland, Australia., Johnston LM; School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Queensland, Australia. |
| المصدر: | International journal of cardiology [Int J Cardiol] 2024 May 15; Vol. 403, pp. 131911. Date of Electronic Publication: 2024 Feb 29. |
| نوع المنشور: | Meta-Analysis; Systematic Review; Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8200291 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1874-1754 (Electronic) Linking ISSN: 01675273 NLM ISO Abbreviation: Int J Cardiol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Amsterdam : Elsevier Original Publication: Amsterdam : Elsevier/North-Holland Biomedical Press, c1981- |
| مواضيع طبية MeSH: | Rheumatic Heart Disease*/diagnostic imaging , Rheumatic Heart Disease*/epidemiology, Child ; Humans ; Adolescent ; Adult ; Follow-Up Studies ; Disease Progression ; Echocardiography ; Heart ; Mass Screening ; Prevalence |
| مستخلص: | Objectives: To estimate progression, regression and persistence rates for borderline and mild-definite latent RHD in children and youth diagnosed at age < 25 years. Methods: A review was conducted in accordance with Preferred Reporting Items for Systematic reviews and Meta-Analysis guidelines. Electronic databases were searched for latent RHD echocardiography follow-up studies which used World Heart Federation diagnostic criteria. A meta-analysis of outcomes was conducted for borderline and mild-definite disease subcategories. Results: Data for 1618 individuals from 12 studies were included. For borderline cases, 48.51% regressed (95%CI 45.10-51.93), 13.99% progressed (95%CI 9.72-18.25), and 38.61% had persistent (unchanged) disease at follow-up (95%CI 29.68-47.54). For mild-definite cases, 34.01% regressed (95%CI 28.88-39.15), 8.06% progressed (95%CI 3.65-16.90), and 60.23% had persistent disease (95%CI 55.08-67.38). Conclusions: Borderline and mild-definite latent RHD show variable evolution following initial diagnosis. While 8% of mild-definite and 14% borderline cases had signs of disease progression at follow-up, a third of mild-definite and half of borderline cases had disease regression, even with sub adequate antibiotic prophylaxis. The significant variability between study cohorts suggests latent RHD natural history is likely variable between different endemic regions globally. Future research is needed to identify those individuals who would most benefit from antibiotic prophylaxis and determine regional natural history of latent RHD. Competing Interests: Declaration of competing interest This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. (Copyright © 2023. Published by Elsevier B.V.) |
| فهرسة مساهمة: | Keywords: Echocardiography; Latent; Natural history; Rheumatic heart disease; Screening |
| تواريخ الأحداث: | Date Created: 20240301 Date Completed: 20240318 Latest Revision: 20240318 |
| رمز التحديث: | 20240318 |
| DOI: | 10.1016/j.ijcard.2024.131911 |
| PMID: | 38428505 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1874-1754 |
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| DOI: | 10.1016/j.ijcard.2024.131911 |