دورية أكاديمية
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Research progress of the effective active ingredients of Astragalus mongholicus in the treatment of diabetic peripheral neuropathy.

التفاصيل البيبلوغرافية
العنوان: Research progress of the effective active ingredients of Astragalus mongholicus in the treatment of diabetic peripheral neuropathy.
المؤلفون: Liu Y; Department of Rehabilitation Medicine,The Affiliated Taian City Central Hospital of Qingdao University, Taian 271000, China., Yu R; Department of Rehabilitation Medicine,The Affiliated Taian City Central Hospital of Qingdao University, Taian 271000, China., Wang X; Department of Rehabilitation Medicine,The Affiliated Taian City Central Hospital of Qingdao University, Taian 271000, China., Chen Y; Department of Skills Training Center,The Affiliated Taian City Central Hospital of Qingdao University, Taian 271000, China., Yin T; Department of Rehabilitation Medicine,The Affiliated Taian City Central Hospital of Qingdao University, Taian 271000, China., Gao Q; Department of Rehabilitation Medicine,The Affiliated Taian City Central Hospital of Qingdao University, Taian 271000, China., Sun L; Department of Rehabilitation Medicine,The Affiliated Taian City Central Hospital of Qingdao University, Taian 271000, China., Zheng Z; Department of Rehabilitation Medicine,The Affiliated Taian City Central Hospital of Qingdao University, Taian 271000, China. Electronic address: zxyyzhengzuncheng@126.com.
المصدر: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Apr; Vol. 173, pp. 116350. Date of Electronic Publication: 2024 Mar 01.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE
أسماء مطبوعة: Publication: Paris : Editions Scientifiques Elsevier
Original Publication: New York, N.Y. : Masson Pub. USA, Inc., c1982-
مواضيع طبية MeSH: Diabetic Neuropathies*/drug therapy , Astragalus Plant* , Drugs, Chinese Herbal*/pharmacology , Drugs, Chinese Herbal*/therapeutic use , Diabetes Mellitus*, Astragalus propinquus
مستخلص: Diabetic peripheral neuropathy (DPN) is one of the most prevalent consequences of diabetes, with a high incidence and disability rate. The DPN's pathogenesis is extremely complex and yet to be fully understood. Persistent high glucose metabolism, nerve growth factor deficiency, microvascular disease, oxidative stress, peripheral nerve cell apoptosis, immune factors, and other factors have been implicated in the pathogenesis of DPN. Astragalus mongholicus is a commonly used plant used to treat DPN in clinical settings. Its rich chemical components mainly include Astragalus polysaccharide, Astragalus saponins, Astragalus flavones, etc., which play a vital role in the treatment of DPN. This review aimed to summarize the pathogenesis of DPN and the studies on the mechanism of the effective components of Astragalus mongholicus in treating DPN. This is of great significance for the effective use of Chinese herbal medicine and the promotion of its status and influence on the world.
Competing Interests: Declaration of Competing Interest All authors disclosed no relevant relationships
(Copyright © 2024 The Authors. Published by Elsevier Masson SAS.. All rights reserved.)
فهرسة مساهمة: Keywords: Active Ingredient of Astragalus Mongholicus; Astragalus flavone; Astragalus mongholicus; Astragalus polysaccharides; Astragalus saponin; Diabetic peripheral neuropathy; Pharmacological mechanism
المشرفين على المادة: 0 (Drugs, Chinese Herbal)
تواريخ الأحداث: Date Created: 20240302 Date Completed: 20240327 Latest Revision: 20240327
رمز التحديث: 20240327
DOI: 10.1016/j.biopha.2024.116350
PMID: 38430632
قاعدة البيانات: MEDLINE
الوصف
تدمد:1950-6007
DOI:10.1016/j.biopha.2024.116350