دورية أكاديمية
Patient-Specific Haemodynamic Analysis of Virtual Grafting Strategies in Type-B Aortic Dissection: Impact of Compliance Mismatch.
العنوان: | Patient-Specific Haemodynamic Analysis of Virtual Grafting Strategies in Type-B Aortic Dissection: Impact of Compliance Mismatch. |
---|---|
المؤلفون: | Girardin L; Department of Mechanical Engineering, University College London, Torrington Place, London, WC1E 7JE, UK.; Wellcome/EPSRC Centre for Interventional and Surgical Sciences (WEISS), University College London, 43-45 Foley Street, London, W1W 7TS, UK., Stokes C; Department of Mechanical Engineering, University College London, Torrington Place, London, WC1E 7JE, UK.; Wellcome/EPSRC Centre for Interventional and Surgical Sciences (WEISS), University College London, 43-45 Foley Street, London, W1W 7TS, UK., Thet MS; Department of Cardiothoracic Surgery, St Bartholomew's Hospital, West Smithfield, London, EC1A 7BE, UK., Oo AY; Department of Cardiothoracic Surgery, St Bartholomew's Hospital, West Smithfield, London, EC1A 7BE, UK., Balabani S; Department of Mechanical Engineering, University College London, Torrington Place, London, WC1E 7JE, UK.; Wellcome/EPSRC Centre for Interventional and Surgical Sciences (WEISS), University College London, 43-45 Foley Street, London, W1W 7TS, UK., Díaz-Zuccarini V; Department of Mechanical Engineering, University College London, Torrington Place, London, WC1E 7JE, UK. v.diaz@ucl.ac.uk.; Wellcome/EPSRC Centre for Interventional and Surgical Sciences (WEISS), University College London, 43-45 Foley Street, London, W1W 7TS, UK. v.diaz@ucl.ac.uk. |
المصدر: | Cardiovascular engineering and technology [Cardiovasc Eng Technol] 2024 Jun; Vol. 15 (3), pp. 290-304. Date of Electronic Publication: 2024 Mar 04. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Springer Country of Publication: United States NLM ID: 101531846 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1869-4098 (Electronic) Linking ISSN: 1869408X NLM ISO Abbreviation: Cardiovasc Eng Technol Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: New York, NY : Springer |
مواضيع طبية MeSH: | Aortic Dissection*/surgery , Aortic Dissection*/physiopathology , Aortic Dissection*/diagnostic imaging , Blood Vessel Prosthesis Implantation*/instrumentation , Blood Vessel Prosthesis Implantation*/adverse effects , Models, Cardiovascular* , Patient-Specific Modeling* , Hemodynamics* , Blood Vessel Prosthesis* , Vascular Stiffness* , Computed Tomography Angiography*, Humans ; Prosthesis Design ; Treatment Outcome ; Magnetic Resonance Imaging, Cine ; Aortography ; Male ; Arterial Pressure ; Middle Aged ; Aortic Aneurysm/surgery ; Aortic Aneurysm/diagnostic imaging ; Aortic Aneurysm/physiopathology ; Stress, Mechanical ; Polyethylene Terephthalates ; Predictive Value of Tests |
مستخلص: | Introduction: Compliance mismatch between the aortic wall and Dacron Grafts is a clinical problem concerning aortic haemodynamics and morphological degeneration. The aortic stiffness introduced by grafts can lead to an increased left ventricular (LV) afterload. This study quantifies the impact of compliance mismatch by virtually testing different Type-B aortic dissection (TBAD) surgical grafting strategies in patient-specific, compliant computational fluid dynamics (CFD) simulations. Materials and Methods: A post-operative case of TBAD was segmented from computed tomography angiography data. Three virtual surgeries were generated using different grafts; two additional cases with compliant grafts were assessed. Compliant CFD simulations were performed using a patient-specific inlet flow rate and three-element Windkessel outlet boundary conditions informed by 2D-Flow MRI data. The wall compliance was calibrated using Cine-MRI images. Pressure, wall shear stress (WSS) indices and energy loss (EL) were computed. Results: Increased aortic stiffness and longer grafts increased aortic pressure and EL. Implementing a compliant graft matching the aortic compliance of the patient reduced the pulse pressure by 11% and EL by 4%. The endothelial cell activation potential (ECAP) differed the most within the aneurysm, where the maximum percentage difference between the reference case and the mid (MDA) and complete (CDA) descending aorta replacements increased by 16% and 20%, respectively. Conclusion: This study suggests that by minimising graft length and matching its compliance to the native aorta whilst aligning with surgical requirements, the risk of LV hypertrophy may be reduced. This provides evidence that compliance-matching grafts may enhance patient outcomes. (© 2024. The Author(s).) |
References: | Int J Numer Method Biomed Eng. 2023 Oct;39(10):e3664. (PMID: 36447341) Circulation. 1996 Jun 1;93(11):2080-7. (PMID: 8640985) BMC Surg. 2020 Nov 3;20(1):266. (PMID: 33143659) Ann Biomed Eng. 2010 Jul;38(7):2302-13. (PMID: 20195758) J Biomech. 2021 Dec 2;129:110793. (PMID: 34715606) J Biomech. 1993 Jan;26(1):59-67. (PMID: 8423169) Ann Thorac Surg. 1995 Apr;59(4):981-9. (PMID: 7695428) J Biomed Mater Res B Appl Biomater. 2011 May;97(2):201-14. (PMID: 21391300) Ann Cardiothorac Surg. 2022 Jan;11(1):1-15. (PMID: 35211380) Biomed Eng Online. 2015 Apr 15;14:34. (PMID: 25881252) Circ J. 2014;78(2):322-8. (PMID: 24292128) J Thorac Dis. 2018 Apr;10(Suppl 9):S978-S982. (PMID: 29850179) J Vasc Surg. 2015 Aug;62(2):279-84. (PMID: 25935270) J Endovasc Ther. 2017 Apr;24(2):281-289. (PMID: 28102102) Med Eng Phys. 2018 May 11;:. (PMID: 29759947) Ann Thorac Surg. 2009 Nov;88(5):1484-91. (PMID: 19853098) Circ Res. 1968 Oct;23(4):567-79. (PMID: 5677947) Ann Cardiothorac Surg. 2014 Jul;3(4):340-50. (PMID: 25133097) Med Eng Phys. 2013 Sep;35(9):1321-30. (PMID: 23523079) BMJ Open. 2019 Mar 4;9(3):e025488. (PMID: 30837256) Clin Radiol. 2016 Aug;71(8):779-95. (PMID: 26944696) Med Eng Phys. 2019 Sep;71:45-55. (PMID: 31257054) Bioengineering (Basel). 2022 Oct 14;9(10):. (PMID: 36290523) J Mech Behav Biomed Mater. 2016 Aug;61:36-44. (PMID: 26826765) J Cardiovasc Transl Res. 2016 Aug;9(4):334-42. (PMID: 27245785) IEEE Trans Biomed Eng. 2019 Dec;66(12):3411-3419. (PMID: 30872222) Biomech Model Mechanobiol. 2021 Apr;20(2):481-490. (PMID: 33068193) Eur Heart J Cardiovasc Imaging. 2023 Apr 24;24(5):e65-e85. (PMID: 36881779) Ann Vasc Surg. 2020 Feb;63:336-381. (PMID: 31344467) Int J Numer Method Biomed Eng. 2017 May;33(5):. (PMID: 27509188) Brain. 2011 Nov;134(Pt 11):3398-407. (PMID: 22075523) J Biomech Eng. 2009 Sep;131(9):091002. (PMID: 19725691) Eur J Vasc Endovasc Surg. 2019 Oct;58(4):521-528. (PMID: 31445862) J Biomech Eng. 2009 Mar;131(3):031001. (PMID: 19154060) Ann Biomed Eng. 2015 Jan;43(1):177-89. (PMID: 25092420) J Vasc Res. 2009;46(5):417-25. (PMID: 19155633) J Endovasc Ther. 2020 Jun;27(3):396-404. (PMID: 32364001) J Vasc Surg. 2019 Dec;70(6):1792-1800.e3. (PMID: 31176640) Comput Biol Med. 2021 Aug;135:104581. (PMID: 34174756) Circulation. 2022 Dec 13;146(24):e334-e482. (PMID: 36322642) Eur J Cardiothorac Surg. 2019 Jun 1;55(6):1061-1070. (PMID: 30535179) Sci Rep. 2019 Jun 13;9(1):8600. (PMID: 31197221) Comput Methods Programs Biomed. 2022 Jun;221:106826. (PMID: 35526507) J Hypertens. 2005 Sep;23(9):1745-50. (PMID: 16093921) Ann Biomed Eng. 2012 Mar;40(3):729-41. (PMID: 22009313) Am J Cardiol. 2022 Nov 01;182:89-94. (PMID: 36068098) J Vasc Surg. 2009 Apr;49(4):1029-36. (PMID: 19341890) Physiol Res. 2009;58 Suppl 2:S119-S140. (PMID: 20131930) J Biomech. 2019 Mar 27;86:132-140. (PMID: 30799078) Comput Biol Med. 2021 Nov;138:104882. (PMID: 34600328) Expert Rev Cardiovasc Ther. 2003 Nov;1(4):581-94. (PMID: 15030257) Int J Cardiol. 2016 May 1;210:28-31. (PMID: 26922709) Front Bioeng Biotechnol. 2021 Oct 18;9:750656. (PMID: 34733832) Circulation. 2011 Dec 13;124(24):2661-9. (PMID: 22104552) Hypertension. 2022 Apr;79(4):836-843. (PMID: 35139665) Nephrol Dial Transplant. 2010 Dec;25(12):3815-23. (PMID: 20947536) J Biomech Eng. 2015 Aug;137(8):081013. (PMID: 26043270) J Thorac Cardiovasc Surg. 2014 Sep;148(3):1082-8; discussion 1088-9. (PMID: 25129601) Ann Biomed Eng. 2021 Sep;49(9):2196-2213. (PMID: 33655419) J Clin Hypertens (Greenwich). 2008 Apr;10(4):295-303. (PMID: 18401227) Radiol Cardiothorac Imaging. 2020 Feb 27;2(1):e190233. (PMID: 33778539) Front Bioeng Biotechnol. 2022 Jun 23;10:825015. (PMID: 35813993) Sci Rep. 2023 Jan 20;13(1):1116. (PMID: 36670162) Med Biol Eng Comput. 2009 Feb;47(2):131-41. (PMID: 18543011) Pol J Radiol. 2020 Dec 15;85:e643-e649. (PMID: 33552316) |
معلومات مُعتمدة: | United Kingdom WT_ Wellcome Trust; NS/A000050/1 Wellcome / EPSRC Centre for Interventional and Surgical Sciences; NH/20/1/34705 United Kingdom BHF_ British Heart Foundation |
فهرسة مساهمة: | Keywords: CFD simulation; Compliance mismatch; Dacron graft; Type-B aortic dissection; Virtual interventions |
المشرفين على المادة: | 0 (Polyethylene Terephthalates) |
تواريخ الأحداث: | Date Created: 20240304 Date Completed: 20240711 Latest Revision: 20240714 |
رمز التحديث: | 20240714 |
مُعرف محوري في PubMed: | PMC11239731 |
DOI: | 10.1007/s13239-024-00713-6 |
PMID: | 38438692 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1869-4098 |
---|---|
DOI: | 10.1007/s13239-024-00713-6 |