دورية أكاديمية

Effectiveness of chitosan phonophoresis on ulnar nerve conduction velocity, pain relief, and functional outcomes for mild to moderate cubital tunnel syndrome: A double-blind randomized controlled trial.

التفاصيل البيبلوغرافية
العنوان: Effectiveness of chitosan phonophoresis on ulnar nerve conduction velocity, pain relief, and functional outcomes for mild to moderate cubital tunnel syndrome: A double-blind randomized controlled trial.
المؤلفون: ElGendy MH; Basic Sciences Department, Faculty of Physical Therapy, Cairo University, Giza, Egypt., Fetoh SA; Faculty of Physical Therapy, October 6 University, Giza, Egypt., Salem SE; Faculty of Physical Therapy, Cairo University, Giza, Egypt., Daihom BA; Faculty of Pharmacy, Cairo University, Giza, Egypt., Fahmy EM; Faculty of Medicine, Cairo University, Giza, Egypt., ElMeligie MM; Faculty of Physical Therapy, Ahram Canadian University, Giza, Egypt. Electronic address: mohamed.elmeligie@acu.edu.eg.
المصدر: Journal of hand therapy : official journal of the American Society of Hand Therapists [J Hand Ther] 2024 Mar 06. Date of Electronic Publication: 2024 Mar 06.
Publication Model: Ahead of Print
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Hanley & Belfus, Inc Country of Publication: United States NLM ID: 8806591 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-004X (Electronic) Linking ISSN: 08941130 NLM ISO Abbreviation: J Hand Ther Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [Philadelphia, PA] : Hanley & Belfus, Inc., [c1987-
مستخلص: Background: Cubital tunnel syndrome (CBTS) impairs hand function, with limited conservative options often leading to surgery. Chitosan neuroregenerative effects delivered via phonophoresis provide a rationale for testing this emerging treatment approach.
Purpose: The primary goal of this research was to assess the impact of chitosan phonophoresis on the conductivity of the ulnar nerve, as well as its effects on pain levels and functional outcomes in individuals diagnosed with mild to moderate CBTS.
Study Design: Double-blind randomized controlled trial.
Methods: This was a prospective, double-blinded, randomized controlled study. The participants consisted of 54 individuals aged between 20-35 years who were randomly assigned using block randomization. The control group (n = 27) received standard hand therapy alone, while the experimental group (n = 27) received both standard hand therapy and chitosan phonophoresis. Both groups underwent three treatment sessions per week, each lasting for 60-72 minutes, over a period of five weeks. Pre- and post-intervention evaluations included assessments of ulnar nerve conduction velocity (NCV), pain assessment using the numerical pain rating scale (NPRS), as well as hand function evaluated using the Quick Disabilities of Arm Shoulder Hand (QuickDASH) questionnaire.
Results: After the intervention, the experimental group significantly improved in all outcome measures compared to the control group. Accordingly, ulnar NCV (MD = 2.233 m/sec; CI = 1.63:2.83; p < 0.001; η 2 p = 0.516), NPRS (MD = -1.11; CI = -1.71: -0.50; p < 0.001; η 2 p = 0.208) and QuickDASH (MD = -2.72; CI = -4.54:0.87; p < 0.007; η 2 p = 0.133).
Conclusions: The study findings suggest that chitosan phonophoresis may have the potential as a supplementary treatment to hand therapy for individuals with mild to moderate CBTS. This approach demonstrated significant improvements in nerve conduction, pain reduction, and enhancement of hand function.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 Elsevier Inc. All rights reserved.)
فهرسة مساهمة: Keywords: Chitosan; Cubital tunnel syndrome; Nerve entrapment syndrome; Phonophoresis; Physical therapy; Randomized controlled trial
تواريخ الأحداث: Date Created: 20240307 Latest Revision: 20240307
رمز التحديث: 20240308
DOI: 10.1016/j.jht.2024.02.006
PMID: 38453574
قاعدة البيانات: MEDLINE
الوصف
تدمد:1545-004X
DOI:10.1016/j.jht.2024.02.006