دورية أكاديمية
Cefazolin as a predictor of urinary cephalosporin activity in indicated Enterobacterales.
العنوان: | Cefazolin as a predictor of urinary cephalosporin activity in indicated Enterobacterales. |
---|---|
المؤلفون: | Bryson AL; Department of Pathology, Virginia Commonwealth University Health System, Richmond, Virginia, USA., Bhalodi A; Scientific and Medical Affairs Consulting, Newton, Pennsylvania, USA., Liesman RM; Department of Pathology and Laboratory Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA., Mathers AJ; Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia Health, Charlottesville, Virginia, USA.; Clinical Microbiology Laboratory, Department of Pathology, University of Virginia Health, Charlottesville, Virginia, USA. |
المصدر: | Journal of clinical microbiology [J Clin Microbiol] 2024 Apr 10; Vol. 62 (4), pp. e0078821. Date of Electronic Publication: 2024 Mar 08. |
نوع المنشور: | Journal Article; Review |
اللغة: | English |
بيانات الدورية: | Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 7505564 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-660X (Electronic) Linking ISSN: 00951137 NLM ISO Abbreviation: J Clin Microbiol Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Washington, American Society for Microbiology. |
مواضيع طبية MeSH: | Cefazolin*/pharmacology , Cefazolin*/therapeutic use , Urinary Tract Infections*/drug therapy , Urinary Tract Infections*/microbiology, Humans ; Cephalosporins/pharmacology ; Cephalothin ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Microbial Sensitivity Tests ; Escherichia coli ; Monobactams |
مستخلص: | Traditionally, cephalothin susceptibility results were used to predict the susceptibility of additional cephalosporins; however, in 2013-2014, the Clinical and Laboratory Standards Institute (CLSI) revisited this practice and determined that cefazolin is a more accurate proxy than cephalothin for uncomplicated urinary tract infections (uUTIs). Therefore, a cefazolin surrogacy breakpoint was established to predict the susceptibility of seven oral cephalosporins for Escherichia coli , Klebsiella pneumoniae , and Proteus mirabilis in the context of uUTIs. Clinical microbiology laboratories face several operational challenges when implementing the cefazolin surrogacy breakpoint, which may lead to confusion for the best path forward. Here, we review the historical context and data behind the surrogacy breakpoints, review PK/PD profiles for oral cephalosporins, discuss challenges in deploying the breakpoint, and highlight the limited clinical outcome data in this space. Competing Interests: The authors declare no conflict of interest. |
References: | Antimicrob Agents Chemother. 1994 Nov;38(11):2612-4. (PMID: 7872756) Drugs. 1972;3(1):9-78. (PMID: 4559812) J Antimicrob Chemother. 1990 Dec;26 Suppl E:21-8. (PMID: 2292526) Antimicrob Agents Chemother. 1982 Feb;21(2):320-2. (PMID: 7073267) Int J Antimicrob Agents. 2020 Oct;56(4):106085. (PMID: 32659466) Clin Infect Dis. 1997 Mar;24(3):457-67. (PMID: 9114201) JAMA Pediatr. 2023 Aug 1;177(8):782-789. (PMID: 37358858) Clin Pediatr (Phila). 2023 Jan;62(1):47-54. (PMID: 35861216) Antimicrob Agents Chemother. 1988 Dec;32(12):1896-8. (PMID: 3245701) J Clin Microbiol. 2007 Nov;45(11):3762-3. (PMID: 17728468) Antimicrob Agents Chemother. 1995 May;39(5):1082-6. (PMID: 7625793) J Clin Pharmacol. 1991 Dec;31(12):1137-45. (PMID: 1761737) Int J Antimicrob Agents. 2000 Jan;13(3):183-7. (PMID: 10724022) JAMA. 2005 Feb 23;293(8):949-55. (PMID: 15728165) Antimicrob Agents Chemother. 1986 Sep;30(3):485-90. (PMID: 3777912) Diagn Microbiol Infect Dis. 2013 Aug;76(4):483-5. (PMID: 23680238) Diagn Microbiol Infect Dis. 2021 Apr;99(4):115299. (PMID: 33460959) Ann Pharmacother. 1996 Mar;30(3):258-68. (PMID: 8833562) JAMA. 2012 Feb 8;307(6):583-9. (PMID: 22318279) Clin Infect Dis. 1993 May;16(5):646-53. (PMID: 8507756) Clin Pharmacol Ther. 1985 Nov;38(5):590-4. (PMID: 4053491) Clin Infect Dis. 2011 Mar 1;52(5):e103-20. (PMID: 21292654) Antimicrob Agents Chemother. 1979 Jul;16(1):1-6. (PMID: 475366) Antimicrob Agents Chemother. 1977 Aug;12(2):157-62. (PMID: 900915) Appl Microbiol. 1970 Apr;19(4):589-93. (PMID: 5418940) Antimicrob Agents Chemother. 1990 Feb;34(2):232-4. (PMID: 2327771) Antimicrob Agents Chemother. 1977 Feb;11(2):331-8. (PMID: 848940) Antimicrob Agents Chemother. 1992 Jan;36(1):144-9. (PMID: 1590680) Antimicrob Agents Chemother. 1985 Oct;28(4):504-7. (PMID: 3878129) Antimicrob Agents Chemother. 1990 Nov;34(11):2047-9. (PMID: 2073095) JAC Antimicrob Resist. 2022 Mar 22;4(2):dlac025. (PMID: 35350132) Antimicrob Agents Chemother. 2003 Mar;47(3):897-900. (PMID: 12604518) Clin Pharmacol Ther. 1993 Sep;54(3):311-6. (PMID: 8375126) J Clin Pharmacol. 1988 Aug;28(8):700-6. (PMID: 3216036) J Antimicrob Chemother. 1990 May;25(5):831-5. (PMID: 2373665) Diagn Microbiol Infect Dis. 2013 Dec;77(4):381-2. (PMID: 24091106) Antimicrob Agents Chemother. 1990 Jun;34(6):1204-9. (PMID: 2393282) Front Pharmacol. 2022 Jun 28;13:900551. (PMID: 35837288) Am J Clin Pathol. 1978 Dec;70(6):909-13. (PMID: 727174) J Fam Pract. 1983 Jul;17(1):135, 138-40. (PMID: 6864165) Diagn Microbiol Infect Dis. 2020 Jul;97(3):115053. (PMID: 32349909) |
فهرسة مساهمة: | Keywords: UTI; antimicrobial susceptibility testing; breakpoints; cefazolin; cefazolin surrogate; oral cephalosporins; uncomplicated UTI; urinary tract infection |
المشرفين على المادة: | IHS69L0Y4T (Cefazolin) 0 (Cephalosporins) R72LW146E6 (Cephalothin) 0 (Anti-Bacterial Agents) 0 (Monobactams) |
تواريخ الأحداث: | Date Created: 20240308 Date Completed: 20240411 Latest Revision: 20240517 |
رمز التحديث: | 20240517 |
مُعرف محوري في PubMed: | PMC11005412 |
DOI: | 10.1128/jcm.00788-21 |
PMID: | 38457194 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1098-660X |
---|---|
DOI: | 10.1128/jcm.00788-21 |