دورية أكاديمية
Longitudinal point-of-care assessment of psychomotor vigilance in children in the epilepsy monitoring unit.
| العنوان: | Longitudinal point-of-care assessment of psychomotor vigilance in children in the epilepsy monitoring unit. |
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| المؤلفون: | Mithani K; Division of Neurosurgery, Hospital for Sick Children, Toronto, Ontario, Canada; Institute of Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada. Electronic address: karim.mithani@utoronto.ca., Wong SM; Institute of Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada; Neurosciences and Mental Health Program, Hospital for Sick Children, Toronto, Ontario, Canada. Electronic address: simeon.wong@sickkids.ca., Suresh H; Division of Neurosurgery, Hospital for Sick Children, Toronto, Ontario, Canada; Institute of Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada. Electronic address: hrishikesh.suresh@sickkids.ca., Yau I; Division of Neurology, Hospital for Sick Children, Toronto, Ontario, Canada. Electronic address: ivanna.yau@sickkids.ca., Kerr EN; Department of Psychology, Hospital for Sick Children, Toronto, Ontario, Canada. Electronic address: elizabeth.kerr@sickkids.ca., Smith ML; Neurosciences and Mental Health Program, Hospital for Sick Children, Toronto, Ontario, Canada; Department of Psychology, University of Toronto Mississauga, Mississauga, Ontario, Canada. Electronic address: marylou.smith@utoronto.ca., Donner E; Division of Neurology, Hospital for Sick Children, Toronto, Ontario, Canada. Electronic address: elizabeth.donner@sickkids.ca., Ibrahim GM; Division of Neurosurgery, Hospital for Sick Children, Toronto, Ontario, Canada; Institute of Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada; Neurosciences and Mental Health Program, Hospital for Sick Children, Toronto, Ontario, Canada. Electronic address: george.ibrahim@sickkids.ca. |
| المصدر: | Epilepsy & behavior : E&B [Epilepsy Behav] 2024 Apr; Vol. 153, pp. 109725. Date of Electronic Publication: 2024 Mar 07. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Academic Press Country of Publication: United States NLM ID: 100892858 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-5069 (Electronic) Linking ISSN: 15255050 NLM ISO Abbreviation: Epilepsy Behav Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: San Diego, CA : Academic Press, c2000- |
| مواضيع طبية MeSH: | Psychomotor Performance*/physiology , Epilepsy*/diagnosis, Child ; Humans ; Point-of-Care Systems ; Wakefulness/physiology ; Reaction Time/physiology |
| مستخلص: | The epilepsy monitoring unit (EMU) is a complex and dynamic operational environment, where the cognitive and behavioural consequences of medical and environmental changes often go unnoticed. The psychomotor vigilance task (PVT) has been used to detect changes in cognition and behaviour in numerous contexts, including among astronauts on spaceflight missions, pilots, and commercial drivers. Here, we piloted serial point-of-care administration of the PVT in children undergoing invasive monitoring in the EMU. Seven children completed the PVT throughout their hospital admission and their performance was associated with daily seizure counts, interictal epileptiform discharges, number of antiseizure medications (ASMs) administered, and sleep quality metrics. Using mixed-effects models, we found that PVT reaction time and accuracy were adversely affected by greater number of ASMs and interictal epileptiform activity. We show that serial point-of-care PVT is simple and feasible in the EMU and may enable greater understanding of individual patient responses to medical and environmental alterations, inform clinical decision-making, and support quality-improvement and research initiatives. Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: The authors whose names are listed above certify that they have NO affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript. (Copyright © 2024 Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Behaviour; Cognition; Epilepsy monitoring unit; Neuropsychology; Psychomotor vigilance |
| تواريخ الأحداث: | Date Created: 20240308 Date Completed: 20240401 Latest Revision: 20240401 |
| رمز التحديث: | 20240401 |
| DOI: | 10.1016/j.yebeh.2024.109725 |
| PMID: | 38458121 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1525-5069 |
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| DOI: | 10.1016/j.yebeh.2024.109725 |