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A potential link between aromatics-induced oviposition repellency behaviors and specific odorant receptor of Aedes albopictus.

التفاصيل البيبلوغرافية
العنوان: A potential link between aromatics-induced oviposition repellency behaviors and specific odorant receptor of Aedes albopictus.
المؤلفون: Yan R; College of Life Sciences, Zhejiang University, Hangzhou, China., Chen P; Institute of Pesticide and Environmental Toxicology, Zhejiang University, Hangzhou, China., Xu Z; Institute of Pesticide and Environmental Toxicology, Zhejiang University, Hangzhou, China., Qian J; Institute of Pesticide and Environmental Toxicology, Zhejiang University, Hangzhou, China., Zhu G; Institute of Pesticide and Environmental Toxicology, Zhejiang University, Hangzhou, China., Jin Y; College of Life Sciences, Zhejiang University, Hangzhou, China., Chen B; The Key Laboratory for Quality Improvement of Agricultural Products of Zhejiang Province, College of Advanced Agricultural Sciences, Zhejiang A&F University, Hangzhou, China., Chen M; The Key Laboratory for Quality Improvement of Agricultural Products of Zhejiang Province, College of Advanced Agricultural Sciences, Zhejiang A&F University, Hangzhou, China.
المصدر: Pest management science [Pest Manag Sci] 2024 Jul; Vol. 80 (7), pp. 3603-3611. Date of Electronic Publication: 2024 Mar 22.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Published for SCI by Wiley Country of Publication: England NLM ID: 100898744 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1526-4998 (Electronic) Linking ISSN: 1526498X NLM ISO Abbreviation: Pest Manag Sci Subsets: MEDLINE
أسماء مطبوعة: Original Publication: West Sussex, UK : Published for SCI by Wiley, c2000-
مواضيع طبية MeSH: Aedes*/drug effects , Aedes*/genetics , Aedes*/physiology , Receptors, Odorant*/genetics , Receptors, Odorant*/metabolism , Oviposition*/drug effects , Insect Repellents*/pharmacology, Animals ; Female ; Male ; Insect Proteins/metabolism ; Insect Proteins/genetics ; Molecular Docking Simulation ; Arthropod Antennae/drug effects ; Arthropod Antennae/physiology
مستخلص: Background: The Asian tiger mosquito, Aedes albopictus, is a competent vector for the spread of several viral arboviruses including dengue, chikungunya, and Zika. Several vital mosquito behaviors linked to survival and reproduction are primarily dependent on a sophisticated olfactory system for semiochemical perception. However, a limited number of studies has hampered our understanding of the relationship between the A. albopictus acute olfactory system and the complex chemical world.
Results: Here, we performed a qRT-PCR assay on antennae from A. albopictus of differing sex, age and physiological states, and found that AalbOr10 was enriched in blood-fed female mosquitoes. We then undertook single sensillum recording to de-orphan AalbOr10 using a panel of physiologically and behaviorally relevant odorants in a Drosophila 'empty neuron' system. The results indicated that AalbOr10 was activated by seven aromatic compounds, all of which hampered egg-laying in blood-fed mosquitoes. Furthermore, using a post-RNA interference oviposition assay, we found that reducing the transcript level of AalbOr10 affected repellent activity mediated by 2-ethylphenol at low concentrations (10 -4 vol/vol). Computational modeling and molecular docking studies suggested that hydrogen bonds to Y68 and Y150 mediated the interaction of 2-ethylphenol with AalbOr10.
Conclusion: We reveal a potential link between aromatics-induced oviposition repellency behaviors and a specific odorant receptor in A. albopictus. Our findings provide a foundation for identifying active semiochemicals for the monitoring or controlling of mosquito populations. © 2024 Society of Chemical Industry.
(© 2024 Society of Chemical Industry.)
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معلومات مُعتمدة: 32300447 National Natural Science Foundation of China
فهرسة مساهمة: Keywords: Aedes albopictus; RNAi; aromatics; odorant receptor; oviposition repellency
المشرفين على المادة: 0 (Receptors, Odorant)
0 (Insect Repellents)
0 (Insect Proteins)
SCR Organism: Aedes albopictus
تواريخ الأحداث: Date Created: 20240308 Date Completed: 20240605 Latest Revision: 20240605
رمز التحديث: 20240605
DOI: 10.1002/ps.8064
PMID: 38458148
قاعدة البيانات: MEDLINE
الوصف
تدمد:1526-4998
DOI:10.1002/ps.8064