دورية أكاديمية

Levels of frailty and frailty progression in older urban- and regional-living First Nations Australians.

التفاصيل البيبلوغرافية
العنوان: Levels of frailty and frailty progression in older urban- and regional-living First Nations Australians.
المؤلفون: Lewis ET; School of Population Health, Faculty of Medicine & Health, University of New South Wales, Samuels Building, UNSW Sydney, NSW 2052, Australia; School of Psychology, Faculty of Science, University of New South Wales, Mathews Building, UNSW Sydney, NSW 2052, Australia; Australian Ageing Futures Institute, University of New South Wales, UNSW Sydney, NSW 2052, Australia; Neuroscience Research Australia, 139 Barker Street, Randwick, NSW 2031, Australia. Electronic address: ebony.lewis@unsw.edu.au., Anstey KJ; School of Psychology, Faculty of Science, University of New South Wales, Mathews Building, UNSW Sydney, NSW 2052, Australia; Australian Ageing Futures Institute, University of New South Wales, UNSW Sydney, NSW 2052, Australia; Neuroscience Research Australia, 139 Barker Street, Randwick, NSW 2031, Australia. Electronic address: k.anstey@unsw.edu.au., Radford K; Australian Ageing Futures Institute, University of New South Wales, UNSW Sydney, NSW 2052, Australia; Neuroscience Research Australia, 139 Barker Street, Randwick, NSW 2031, Australia. Electronic address: k.radford@unsw.edu.au., Mealing N; Neuroscience Research Australia, 139 Barker Street, Randwick, NSW 2031, Australia. Electronic address: nicole@simplifystats.com.au., Cardona M; School of Psychology, The University of Queensland, McElwain Building, St Lucia, QLD 4072, Australia; Institute for Evidence-Based Healthcare, Bond University, 14 University Drive, Robina, QLD 4266, Australia. Electronic address: m.cardona@uq.edu.au., Withall A; School of Psychology, Faculty of Science, University of New South Wales, Mathews Building, UNSW Sydney, NSW 2052, Australia; Australian Ageing Futures Institute, University of New South Wales, UNSW Sydney, NSW 2052, Australia. Electronic address: a.withall@unsw.edu.au., Rockwood K; Division of Geriatric Medicine, Dalhousie University, 5955 Veterans Memorial Lane, Halifax, NS B3H 2E1, Canada. Electronic address: kenneth.rockwood@dal.ca., Peters R; Australian Ageing Futures Institute, University of New South Wales, UNSW Sydney, NSW 2052, Australia; Neuroscience Research Australia, 139 Barker Street, Randwick, NSW 2031, Australia; The George Institute for Global Health, Faculty of Medicine & Health, University of New South Wales, Level 18/300 Barangaroo Avenue, Barangaroo, NSW 2000, Australia. Electronic address: rpeters@georgeinstitute.org.au.
المصدر: Maturitas [Maturitas] 2024 May; Vol. 183, pp. 107962. Date of Electronic Publication: 2024 Mar 05.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier/North Holland Biomedical Press Country of Publication: Ireland NLM ID: 7807333 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4111 (Electronic) Linking ISSN: 03785122 NLM ISO Abbreviation: Maturitas Subsets: MEDLINE
أسماء مطبوعة: Publication: Limerick : Elsevier/North Holland Biomedical Press
Original Publication: Amsterdam, Elsevier/North Holland Biomedical Press.
مواضيع طبية MeSH: Frailty*/epidemiology , Australian Aboriginal and Torres Strait Islander Peoples*, Aged ; Humans ; Australia/epidemiology ; Frail Elderly ; Geriatric Assessment
مستخلص: Objectives: To explore the prevalence of frailty, association between frailty and mortality, and transitions between frailty states in urban- and regional-living First Nations Australians.
Study Design: Secondary analysis of longitudinal data from the Koori Growing Old Well Study. First Nations Australians aged 60 years or more from five non-remote communities were recruited in 2010-2012 and followed up six years later (2016-2018). Data collected at both visits were used to derive a 38-item Frailty Index (FI). The FI (range 0-1.0) was classified as robust (<0.1), pre-frail (0.1- < 0.2), mildly (0.2- < 0.3), moderately (0.3- < 0.4) or severely frail (≥0.4).
Main Outcome Measures: Association between frailty and mortality, examined using logistic regression and transitions in frailty (the percentage of participants who changed frailty category) during follow-up.
Results: At baseline, 313 of 336 participants (93 %) had sufficient data to calculate a FI. Median FI score was 0.26 (interquartile range 0.21-0.39); 4.79 % were robust, 20.1 % pre-frail, 31.6 % mildly frail, 23.0 % moderately frail and 20.5 % severely frail. Higher baseline frailty was associated with mortality among severely frail participants (adjusted odds ratio 7.11, 95 % confidence interval 2.51-20.09) but not moderately or mildly frail participants. Of the 153 participants with a FI at both baseline and follow-up, their median FI score increased from 0.26 to 0.28.
Conclusions: Levels of frailty in this First Nations cohort are substantially higher than in similar-aged non-Indigenous populations. Screening for frailty before the age of 70 years may be warranted in First Nations Australians. Further research is urgently needed to determine the factors that are driving such high levels of frailty and propose solutions to prevent or manage frailty in this population.
Competing Interests: Declaration of competing interest The authors declare that they have no competing interest.
(Copyright © 2024 The Author(s). Published by Elsevier B.V. All rights reserved.)
فهرسة مساهمة: Keywords: Epidemiology; Frailty; Indigenous peoples; Older adults
تواريخ الأحداث: Date Created: 20240310 Date Completed: 20240408 Latest Revision: 20240408
رمز التحديث: 20240409
DOI: 10.1016/j.maturitas.2024.107962
PMID: 38461558
قاعدة البيانات: MEDLINE
الوصف
تدمد:1873-4111
DOI:10.1016/j.maturitas.2024.107962