دورية أكاديمية
Challenges of animals shelters in caring for dogs infected with Leishmania and other pathogens.
| العنوان: | Challenges of animals shelters in caring for dogs infected with Leishmania and other pathogens. |
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| المؤلفون: | da Silva AS; Postgraduate Program in Development and Environment, Federal University of Rio Grande do Norte, Natal 59078-900, Rio Grande do Norte, Brazil., de Medeiros Silva MM; Postgraduate Program in Development and Environment, Federal University of Rio Grande do Norte, Natal 59078-900, Rio Grande do Norte, Brazil., de Oliveira Mendes Aguiar C; Institute of Tropical Medicine of Rio Grande do Norte, Federal University of Rio Grande do Norte, Natal 59078-900, Rio Grande do Norte, Brazil., Nascimento PRP; Institute of Tropical Medicine of Rio Grande do Norte, Federal University of Rio Grande do Norte, Natal 59078-900, Rio Grande do Norte, Brazil., da Costa EG; Department of Statistics, Federal University of Rio Grande do Norte, Natal 59078-900, Rio Grande do Norte, Brazil., Jeronimo SMB; Institute of Tropical Medicine of Rio Grande do Norte, Federal University of Rio Grande do Norte, Natal 59078-900, Rio Grande do Norte, Brazil; Department of Biochemistry, Biosciences Center, Federal University of Rio Grande do Norte, Natal 59078-900, Rio Grande do Norte, Brazil., de Melo Ximenes MFF; Postgraduate Program in Development and Environment, Federal University of Rio Grande do Norte, Natal 59078-900, Rio Grande do Norte, Brazil; Department of Microbiology and Parasitology, Biosciences Center, Federal University of Rio Grande do Norte, Natal 59078-900, Rio Grande do Norte, Brazil. Electronic address: maria.ximenes@ufrn.br. |
| المصدر: | Veterinary parasitology, regional studies and reports [Vet Parasitol Reg Stud Reports] 2024 Apr; Vol. 49, pp. 100988. Date of Electronic Publication: 2024 Feb 15. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101680410 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2405-9390 (Electronic) Linking ISSN: 24059390 NLM ISO Abbreviation: Vet Parasitol Reg Stud Reports Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Amsterdam : Elsevier, [2015]- |
| مواضيع طبية MeSH: | Leishmaniasis, Visceral*/parasitology , Leishmaniasis, Visceral*/veterinary , Leishmaniasis*/drug therapy , Leishmaniasis*/veterinary , Leishmania infantum*/genetics , Babesia* , Psychodidae*/parasitology , Dog Diseases*/epidemiology, Humans ; Animals ; Dogs |
| مستخلص: | The incidence of human Visceral Leishmaniasis (VL) has decreased in Brazil; however, the number of areas reporting human and canine cases has increased, with Leishmania infantum usually preceding human infection. This study aimed to analyze the profile of infectious diseases that are endemic for both human and canine VL, in dogs housed in a shelter located in the state of Rio Grande do Norte, Northeast Brazil. Data was obtained between November/2021 to April/2022. All dogs residing at the shelter (98 dogs) were examined and blood was collected for testing for L. infantum, Ehrlichia canis, and Babesia sp. Statistical analyses considered the clinical and laboratory findings. Of the 98 animals, approximately 43% were positive for L. infantum antibodies, 19% were positive for L. infantum kDNA, and 18% were L. infantum positive by culture. Greater levels of anti-leishmania antibodies were observed in dogs with symptoms suggestive of VL. The dogs tested positive for E. canis (19/98) and B. canis (18/98). Lutzomyia longipalpis was captured inside the shelter, representing 74.25% (n = 225) of whole sandflies in the dog shelter. Concomitant infection by L. infantum and E. canis increased the odds of death. Treatment of VL included the use of allopurinol (n = 48) and miltefosine (n = 8). Treated animals showed more signs of Leishmania infection. Tickborn parasites and Leishmania were prevalent in sheltered dogs in a VL-endemic area, which increases the odds of death and poses an additional challenge for caring for abandoned dogs and at the same time setting protocols to manage reservoirs of L. infantum. Competing Interests: Declaration of competing interest The authors declare no competing interests. (Copyright © 2024 Elsevier B.V. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Babesia spp; Ehrlichia canis; Leishmania infantum; One health; Sustainable Development Goals (SDG) |
| تواريخ الأحداث: | Date Created: 20240310 Date Completed: 20240312 Latest Revision: 20240502 |
| رمز التحديث: | 20240502 |
| DOI: | 10.1016/j.vprsr.2024.100988 |
| PMID: | 38462297 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2405-9390 |
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| DOI: | 10.1016/j.vprsr.2024.100988 |