دورية أكاديمية
Addressing Unmet PrEP Needs in Women: Impact of a Laboratory-Driven Protocol at an Urban, Essential Hospital.
| العنوان: | Addressing Unmet PrEP Needs in Women: Impact of a Laboratory-Driven Protocol at an Urban, Essential Hospital. |
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| المؤلفون: | Stewart J; Section of Infectious Disease, Boston University Chobanian and Avedisian School of Medicine and Boston Medical Center, Boston, Massachusetts, USA., Ruiz-Mercado G; Section of Infectious Disease, Boston University Chobanian and Avedisian School of Medicine and Boston Medical Center, Boston, Massachusetts, USA.; Grayken Center for Addiction, Boston Medical Center, Boston, Massachusetts, USA., Sperring H; Section of Infectious Disease, Boston University Chobanian and Avedisian School of Medicine and Boston Medical Center, Boston, Massachusetts, USA., Pierre CM; Section of Infectious Disease, Boston University Chobanian and Avedisian School of Medicine and Boston Medical Center, Boston, Massachusetts, USA., Assoumou SA; Section of Infectious Disease, Boston University Chobanian and Avedisian School of Medicine and Boston Medical Center, Boston, Massachusetts, USA., Taylor JL; Section of General Internal Medicine, Boston University Chobanian and Avedisian School of Medicine and Boston Medical Center, Boston, Massachusetts, USA.; Grayken Center for Addiction, Boston Medical Center, Boston, Massachusetts, USA. |
| المصدر: | Open forum infectious diseases [Open Forum Infect Dis] 2024 Feb 01; Vol. 11 (3), pp. ofae056. Date of Electronic Publication: 2024 Feb 01 (Print Publication: 2024). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Published by Oxford University Press on behalf of the Infectious Diseases Society of America Country of Publication: United States NLM ID: 101637045 Publication Model: eCollection Cited Medium: Print ISSN: 2328-8957 (Print) Linking ISSN: 23288957 NLM ISO Abbreviation: Open Forum Infect Dis Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Cary, NC : Published by Oxford University Press on behalf of the Infectious Diseases Society of America, [2014]- |
| مستخلص: | Background: HIV pre-exposure prophylaxis (PrEP) uptake in women remains low. We developed a laboratory result-driven protocol to link women with a positive bacterial sexually transmitted infection (STI) to HIV PrEP at an urban safety-net hospital. Methods: Electronic health records of women with positive chlamydia, gonorrhea, and/or syphilis tests were reviewed, and those eligible for PrEP were referred for direct or primary care provider-driven outreach. We assessed the proportion of women with STIs who received PrEP offers, acceptance, and prescriptions before (July 1, 2018-December 31, 2018) and after (January 1, 2019-June 30, 2020) implementation to evaluate changes in the delivery of key elements of the PrEP care cascade (ie, PrEP offers, acceptance, and prescribing) for women with STIs after protocol implementation. Results: The proportion of women who received PrEP offers increased from 7.6% to 17.6% ( P < .001). After multivariable adjustment, only the postintervention period was associated with PrEP offers (odds ratio [OR], 2.49; 95% CI, 1.68-3.68). In subgroup analyses, PrEP offers increased significantly among non-Hispanic Black (OR, 2.75; 95% CI, 1.65-4.58) and Hispanic (OR, 5.34; 95% CI, 1.77-16.11) women but not among non-Hispanic White women (OR, 1.49; 95% CI, 0.54-4.05). Significant changes in PrEP acceptance and prescriptions were not observed in the sample overall. Conclusions: A laboratory result-driven protocol was associated with a significant increase in PrEP offers to Black and Hispanic women with STI. These results provide concrete suggestions for health systems seeking to increase PrEP access and equity among women. Competing Interests: Potential conflicts of interest. G.R.M. and H.S. are partially funded by the Frontlines of Communities in the United States (FOCUS) grant from Gilead Sciences, which supports HIV, hepatitis C virus, and hepatitis C virus screening and linkage to care. Gilead Sciences had no role in the development of this research. All other authors report no potential conflicts. (© The Author(s) 2024. Published by Oxford University Press on behalf of Infectious Diseases Society of America.) |
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| معلومات مُعتمدة: | K23 DA044085 United States DA NIDA NIH HHS |
| فهرسة مساهمة: | Keywords: HIV pre-exposure prophylaxis (PrEP); HIV prevention; care disparities; sexually transmitted infection; women’s health |
| تواريخ الأحداث: | Date Created: 20240311 Latest Revision: 20240328 |
| رمز التحديث: | 20240329 |
| مُعرف محوري في PubMed: | PMC10921387 |
| DOI: | 10.1093/ofid/ofae056 |
| PMID: | 38464490 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2328-8957 |
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| DOI: | 10.1093/ofid/ofae056 |