دورية أكاديمية

Efficacy of intraoperative blood salvage and autotransfusion in living-donor liver transplantation: a retrospective cohort study.

التفاصيل البيبلوغرافية
العنوان: Efficacy of intraoperative blood salvage and autotransfusion in living-donor liver transplantation: a retrospective cohort study.
المؤلفون: Lee J; Yonsei University College of Medicine, Seoul, Korea., Park S; Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea., Lee JG; Department of Transplantation Surgery, Yonsei University College of Medicine, Seoul, Korea., Choo S; Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea., Koo BN; Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea.
المصدر: Korean journal of anesthesiology [Korean J Anesthesiol] 2024 Jun; Vol. 77 (3), pp. 345-352. Date of Electronic Publication: 2024 Mar 12.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Korean Society of Anesthesiologists Country of Publication: Korea (South) NLM ID: 101502451 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2005-7563 (Electronic) Linking ISSN: 20056419 NLM ISO Abbreviation: Korean J Anesthesiol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Seoul : Korean Society of Anesthesiologists
مواضيع طبية MeSH: Liver Transplantation*/methods , Operative Blood Salvage*/methods , Blood Transfusion, Autologous*/methods , Living Donors*, Humans ; Male ; Female ; Retrospective Studies ; Middle Aged ; Adult ; Cohort Studies ; Blood Loss, Surgical/prevention & control ; Erythrocyte Transfusion/methods ; Treatment Outcome
مستخلص: Background: Liver transplantation (LT) may be associated with massive blood loss and the need for allogeneic blood transfusion. Intraoperative blood salvage autotransfusion (IBSA) can reduce the need for allogeneic blood transfusion. This study aimed to investigate the effectiveness of blood salvage in LT.
Methods: Among 355 adult patients who underwent elective living-donor LT between January 1, 2019, and December 31, 2022, 59 recipients without advanced hepatocellular carcinoma received IBSA using Cell Saver (CS group). Based on sex, age, model for end-stage liver disease (MELD) score, preoperative laboratory results, and other factors, 118 of the 296 recipients who did not undergo IBSA were matched using propensity score (non-CS group). The primary outcome was the amount of intraoperative allogenic red blood cell (RBC) transfusion. Comparisons were made between the two groups regarding the amount of other blood components transfused and postoperative laboratory findings.
Results: The transfused allogeneic RBC for the CS group was significantly lower than that of the non-CS group (1,506.0 vs. 1,957.5 ml, P = 0.026). No significant differences in the transfused total fresh frozen plasma, platelets, cryoprecipitate, and estimated blood loss were observed between the two groups. The postoperative allogeneic RBC transfusion was significantly lower in the CS group than in the non-CS group (1,500.0 vs. 2,100.0 ml, P = 0.039). No significant differences in postoperative laboratory findings were observed at postoperative day 1 and discharge.
Conclusions: Using IBSA during LT can effectively reduce the need for perioperative allogeneic blood transfusions without causing subsequent coagulopathy.
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فهرسة مساهمة: Keywords: Autologous blood transfusion; Autotransfusion; Blood coagulation; Blood transfusion; Liver transplantation; Operative blood salvage; Postoperative complications.
تواريخ الأحداث: Date Created: 20240311 Date Completed: 20240605 Latest Revision: 20240611
رمز التحديث: 20240611
مُعرف محوري في PubMed: PMC11150109
DOI: 10.4097/kja.23599
PMID: 38467466
قاعدة البيانات: MEDLINE
الوصف
تدمد:2005-7563
DOI:10.4097/kja.23599