دورية أكاديمية
أعرض في EDS

Prevalence, incidence, and trends of epilepsy among children and adolescents in Africa: a systematic review and meta-analysis.

التفاصيل البيبلوغرافية
العنوان: Prevalence, incidence, and trends of epilepsy among children and adolescents in Africa: a systematic review and meta-analysis.
المؤلفون: Biset G; Department of Pediatrics and Child Health Nursing, School of Nursing and Midwifery, College of Medicine and Health Sciences, Wollo University, Dessie, P.O.BOX: 1145, Ethiopia. gebeyawbiset@yahoo.com., Abebaw N; Department of Midwifery, School of Nursing and Midwifery, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia., Gebeyehu NA; School of Midwifery, College of Health Sciences and Medicine, Wolaita Sodo University, Wolaita Sodo, Ethiopia., Estifanos N; Department of Nursing, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia., Birrie E; Department of Pediatrics and Child Health Nursing, School of Nursing and Midwifery, College of Medicine and Health Sciences, Wollo University, Dessie, P.O.BOX: 1145, Ethiopia., Tegegne KD; Department of Nursing, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.
المصدر: BMC public health [BMC Public Health] 2024 Mar 12; Vol. 24 (1), pp. 771. Date of Electronic Publication: 2024 Mar 12.
نوع المنشور: Meta-Analysis; Systematic Review; Journal Article
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100968562 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2458 (Electronic) Linking ISSN: 14712458 NLM ISO Abbreviation: BMC Public Health Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BioMed Central, [2001-
مواضيع طبية MeSH: Quality of Life* , Epilepsy*/epidemiology, Child ; Humans ; Adolescent ; Prevalence ; Incidence ; Africa/epidemiology
مستخلص: Background: Epilepsy contributes to a significant disease burden in children and adolescents worldwide. The incidence of childhood epilepsy is threefold higher in low and middle income countries compared in high-income countries. Epilepsy is a serious neurological condition associated with stigma and discrimination, an impaired quality of life, and other mental health related problems.
Objective: This study is aimed to synthesize existing evidence and estimate the pooled prevalence and incidence of epilepsy in children and adolescents in Africa.
Methods: A comprehensive and systematic search of relevant databases was conducted. The quality of each study was assessed using the Newcastle-Ottawa Quality Assessment Scale adapted for meta-analysis. Two reviewers screened retrieved articles, conducted critical appraisals, and extracted the data. Heterogeneity between studies was assessed by visual inspection of forest plots and statistically using Cochran's Q statistics and the I 2 test. Publication bias was checked by visual inspection of funnel plots as well as statistically using Egger's correlation and Begg's regression tests. Finally, the pooled prevalence and incidence of childhood epilepsy were computed with 95% confidence intervals.
Result: In this review and meta-analysis 42 studies with 56 findings were included to compute the pooled prevalence of childhood epilepsy. On the other hand, 6 studies were included to estimate the combined incidence. The pooled prevalence of cumulative epilepsy was 17.3 per 1000 children. Whereas the pooled prevalence of active and lifetime epilepsy was 6.8 and 18.6 per 1000 children respectively. The pooled incidence of childhood epilepsy was 2.5 per 1000 children.
Conclusion: Nearly 1 in 50 children are suffering from epilepsy in Africa. However, little attention has been paid to the prevention and treatment of childhood epilepsy. Mass epilepsy screening, scaling up treatment coverage, and designing strict treatment follow up and monitoring mechanisms are recommended.
(© 2024. The Author(s).)
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فهرسة مساهمة: Keywords: Africa; Children and adolescents; Epilepsy; Prevalence
تواريخ الأحداث: Date Created: 20240313 Date Completed: 20240314 Latest Revision: 20240315
رمز التحديث: 20240315
مُعرف محوري في PubMed: PMC10935902
DOI: 10.1186/s12889-024-18236-z
PMID: 38475724
قاعدة البيانات: MEDLINE
الوصف
تدمد:1471-2458
DOI:10.1186/s12889-024-18236-z