دورية أكاديمية
HealthCall: Smartphone Enhancement of Brief Interventions to Improve HIV Medication Adherence Among Patients in HIV Care.
| العنوان: | HealthCall: Smartphone Enhancement of Brief Interventions to Improve HIV Medication Adherence Among Patients in HIV Care. |
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| المؤلفون: | Knox J; Columbia University Irvine Medical Center, 722 West 168th street, New York, NY, 10032, USA. justinryanknox@gmail.com.; New York State Psychiatric Institute, New York, NY, USA. justinryanknox@gmail.com.; Mailman School of Public Health, Columbia University, New York, NY, USA. justinryanknox@gmail.com., Aharonovich E; Columbia University Irvine Medical Center, 722 West 168th street, New York, NY, 10032, USA.; New York State Psychiatric Institute, New York, NY, USA., Zingman BS; Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY, USA., Stohl M; New York State Psychiatric Institute, New York, NY, USA., Walsh C; New York State Psychiatric Institute, New York, NY, USA., Elliott JC; Columbia University Irvine Medical Center, 722 West 168th street, New York, NY, 10032, USA.; New York State Psychiatric Institute, New York, NY, USA., Fink DS; New York State Psychiatric Institute, New York, NY, USA., Durant S; Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY, USA., Menchaca R; Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY, USA., Sharma A; Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY, USA., Denning M; New York State Psychiatric Institute, New York, NY, USA., Hasin D; Columbia University Irvine Medical Center, 722 West 168th street, New York, NY, 10032, USA.; New York State Psychiatric Institute, New York, NY, USA.; Mailman School of Public Health, Columbia University, New York, NY, USA. |
| المصدر: | AIDS and behavior [AIDS Behav] 2024 Jun; Vol. 28 (6), pp. 1912-1922. Date of Electronic Publication: 2024 Mar 13. |
| نوع المنشور: | Journal Article; Randomized Controlled Trial |
| اللغة: | English |
| بيانات الدورية: | Publisher: Springer Science + Business Media Country of Publication: United States NLM ID: 9712133 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-3254 (Electronic) Linking ISSN: 10907165 NLM ISO Abbreviation: AIDS Behav Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2005- : New York, NY : Springer Science + Business Media Original Publication: New York, NY : Plenum Press, 1997- |
| مواضيع طبية MeSH: | Medication Adherence*/psychology , Medication Adherence*/statistics & numerical data , HIV Infections*/drug therapy , HIV Infections*/psychology , Smartphone* , Motivational Interviewing* , Anti-HIV Agents*/therapeutic use, Humans ; Male ; Female ; Middle Aged ; Adult ; Alcoholism/therapy ; Alcoholism/psychology ; Treatment Outcome |
| مستخلص: | Heavy drinking among people living with HIV (PLWH) reduces ART adherence and worsens health outcomes. Lengthy interventions are not feasible in most HIV care settings, and patients infrequently follow referrals to outside treatment. Utilizing visual and video features of smartphone technology, we developed HealthCall as an electronic means of increasing patient involvement in a brief intervention to reduce drinking and improve ART adherence. The objective of the current study is to evaluate the efficacy of HealthCall to improve ART adherence among PLWH who drink heavily when paired with two brief interventions: the National Institute on Alcoholism and Alcohol Abuse (NIAAA) Clinician's Guide (CG) or Motivational Interviewing (MI). Therefore, we conducted a 1:1:1 randomized trial among 114 participants with alcohol dependence at a large urban HIV clinic. Participants were randomized to one of three groups: (1) CG only (n = 37), (2) CG and HealthCall (n = 38), or (3) MI and HealthCall (n = 39). Baseline interventions targeting drinking reduction and ART adherence were ~ 25 min, with brief (10-15 min) booster sessions at 30 and 60 days. The outcome was ART adherence assessed using unannounced phone pill-count method (possible adherence scores: 0-100%) at 30-day, 60-day, 3, 6, and 12 months. Analyses were conducted using generalized linear mixed models with pre-planned contrasts. Of the 114 enrolled patients, 58% were male, 75% identified as Black/African American, 28% were Hispanic, and 62% had less than a high school education. The mean age was 47.5 years (standard deviation [SD] 10 years) and the mean number of years since they were diagnosed with HIV was 18.6 (SD 7.6). Participants assigned to HealthCall to extend the CG had increased levels of ART adherence at 60-day and 6-month follow-up (compared to CG only), although there was no statistically significant difference by 12-month follow-up. Participants who were assigned to HealthCall to extend the MI never had statistically significant higher levels of ART adherence. These results suggest that the use of a smartphone app can be used to initially extend the reach of a brief drinking intervention to improve ART adherence over a short period of time; however, sustained long-term improvements in ART adherence after intervention activity ends remains a challenge. (© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.) |
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| معلومات مُعتمدة: | R01AA023163 United States AA NIAAA NIH HHS; K01AA028199 United States AA NIAAA NIH HHS; R01DA054553 United States DA NIDA NIH HHS; R01DA057351 United States DA NIDA NIH HHS; R21DA053156 United States DA NIDA NIH HHS; K99DA055724 United States DA NIDA NIH HHS; P30MH43520 United States MH NIMH NIH HHS; R01AA023163 United States AA NIAAA NIH HHS; K01AA028199 United States AA NIAAA NIH HHS; R01DA054553 United States DA NIDA NIH HHS; R01DA057351 United States DA NIDA NIH HHS; R21DA053156 United States DA NIDA NIH HHS; K99DA055724 United States DA NIDA NIH HHS; P30MH43520 United States MH NIMH NIH HHS |
| فهرسة مساهمة: | Keywords: ART adherence; Alcohol use; HIV; Intervention; mHealth |
| المشرفين على المادة: | 0 (Anti-HIV Agents) |
| تواريخ الأحداث: | Date Created: 20240313 Date Completed: 20240607 Latest Revision: 20240607 |
| رمز التحديث: | 20240607 |
| DOI: | 10.1007/s10461-024-04289-z |
| PMID: | 38478322 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1573-3254 |
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| DOI: | 10.1007/s10461-024-04289-z |