دورية أكاديمية
أعرض في EDS

Adherence and factors influencing adherence to glaucoma medications among adult glaucoma patients in Ethiopia: A systematic review and meta-analysis.

التفاصيل البيبلوغرافية
العنوان: Adherence and factors influencing adherence to glaucoma medications among adult glaucoma patients in Ethiopia: A systematic review and meta-analysis.
المؤلفون: Abore KW; Department of Ophthalmology, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.; Department of Pediatrics, Yirgalem Hospital Medical College, Yirgalem, Sidama, Ethiopia., Fole EB; Department of Medicine, Yirgalem Hospital Medical College, Yirgalem, Sidama, Ethiopia., Abebe MT; Department of Medicine, Yirgalem Hospital Medical College, Yirgalem, Sidama, Ethiopia., Tekle NF; Long Term Care Department, Burjeel Medical City, Abu Dhabi, United Arab Emirates., Tilahun RB; Long Term Care Department, Burjeel Medical City, Abu Dhabi, United Arab Emirates., Chinkey FD; Bin Haider Healthcare Center, Dubai, United Arab Emirates., Abera MT; Department of Radiology, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
المصدر: PloS one [PLoS One] 2024 Mar 13; Vol. 19 (3), pp. e0293047. Date of Electronic Publication: 2024 Mar 13 (Print Publication: 2024).
نوع المنشور: Meta-Analysis; Systematic Review; Journal Article
اللغة: English
بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One
أسماء مطبوعة: Original Publication: San Francisco, CA : Public Library of Science
مواضيع طبية MeSH: Glaucoma*/drug therapy , Medication Adherence*/statistics & numerical data, Humans ; Ethiopia/epidemiology ; Intraocular Pressure/drug effects ; Antihypertensive Agents/therapeutic use ; Adult ; Risk Factors
مستخلص: Background: Intraocular pressure is the only modifiable risk factor for the development and progression of glaucoma. Raised intraocular pressure could cause progressive visual field loss and blindness if left uncontrolled. Adherence to ocular hypotensive medications is vital to prevent optic nerve damage and its consequences. This study was conducted to systematically summarize the magnitude of glaucoma medication adherence and factors influencing adherence to glaucoma medications among adult glaucoma patients in Ethiopia.
Methods: Database searches to identify research articles were conducted on PubMed, EMBASE, Cochrane, AJOL, SCOPUS, and Google Scholar without restriction on the date of publication. Data extraction was done using a data extraction Excel sheet. Analysis was performed using STATA version 16. Heterogeneity was assessed using I2 statistics. Pooled prevalence and pooled odds ratio with a 95% confidence interval using a random effect model were computed.
Result: We included six studies with a total of 2101 participants for meta-analysis. The magnitude of adherence to glaucoma medication was found to be 49.46% (95% CI [41.27-57.66]). Urban residents (OR = 1.89, 95% CI; 1.29-2.49) and those with normal visual acuity (OR = 2.82, 95% CI; 0.85-4.80) had higher odds of adherence to glaucoma medications. Patients who pay for the medications themselves (OR = 0.22, 95% CI; 0.09-0.34) were found to have 78% lower odds of adherence than their counterparts.
Conclusion: The magnitude of glaucoma medication adherence is lower than expected. Place of residence, visual acuity, and payment means had statistically significant associations with glaucoma medication adherence. Tailored health education on medication adherence and subsidization of glaucoma medication is recommended.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright: © 2024 Abore et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
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المشرفين على المادة: 0 (Antihypertensive Agents)
تواريخ الأحداث: Date Created: 20240313 Date Completed: 20240807 Latest Revision: 20240807
رمز التحديث: 20240808
مُعرف محوري في PubMed: PMC10936902
DOI: 10.1371/journal.pone.0293047
PMID: 38478513
قاعدة البيانات: MEDLINE
الوصف
تدمد:1932-6203
DOI:10.1371/journal.pone.0293047