دورية أكاديمية
أعرض في EDS

Borophene Quantum Dots as Novel Peroxidase-Mimicking Nanozyme: A Dual-Mode Assay for the Detection of Oxytetracycline and Tetracycline Antibiotics.

التفاصيل البيبلوغرافية
العنوان: Borophene Quantum Dots as Novel Peroxidase-Mimicking Nanozyme: A Dual-Mode Assay for the Detection of Oxytetracycline and Tetracycline Antibiotics.
المؤلفون: Gogoi D; Materials Sciences and Technology Division, CSIR North-East Institute of Science and Technology, Jorhat 785006, Assam, India., Hazarika C; Materials Sciences and Technology Division, CSIR North-East Institute of Science and Technology, Jorhat 785006, Assam, India., Neog G; Materials Sciences and Technology Division, CSIR North-East Institute of Science and Technology, Jorhat 785006, Assam, India., Mridha P; Centre for Preclinical Studies, CSIR-North East Institute of Science and Technology, Jorhat 785006, Assam, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India., Bora HK; Centre for Preclinical Studies, CSIR-North East Institute of Science and Technology, Jorhat 785006, Assam, India., Das MR; Materials Sciences and Technology Division, CSIR North-East Institute of Science and Technology, Jorhat 785006, Assam, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India., Szunerits S; Université Lille, CNRS, Université Polytechnique Hauts-de-France, IEMN, UMR 8520, Lille F-59000, France., Boukherroub R; Université Lille, CNRS, Université Polytechnique Hauts-de-France, IEMN, UMR 8520, Lille F-59000, France.
المصدر: ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2024 Mar 27; Vol. 16 (12), pp. 14645-14660. Date of Electronic Publication: 2024 Mar 13.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101504991 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1944-8252 (Electronic) Linking ISSN: 19448244 NLM ISO Abbreviation: ACS Appl Mater Interfaces Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Washington, D.C. : American Chemical Society
مواضيع طبية MeSH: Quantum Dots* , Oxytetracycline* , Sulfonic Acids* , Benzothiazoles*, Peroxidase ; Chromogenic Compounds ; Hydrogen Peroxide/analysis ; Peroxidases ; Anti-Bacterial Agents/analysis ; Tetracycline ; Colorimetry/methods ; Water
مستخلص: The greater advantages and wide applications of zero-dimensional nanodots inspire researchers to develop new materials. Therefore, novel borophene quantum dots (QDs) were prepared by a hydrothermal liquid exfoliation technique using water medium. The borophene QDs proved to be highly stable in water medium for more than 120 days. The synthesized borophene QDs revealed intrinsic peroxidase mimetic activity using two chromogenic substrates, 3,3',5,5'-tetramethylbenzidine (TMB) and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)diammonium salt (ABTS). The excellent intrinsic peroxidase activity toward TMB and ABTS substrates was executed using optimal reaction conditions (pH, borophene QDs' concentration, incubation time, and temperature). The formation of hydroxyl radicals in the presence of H 2 O 2 upon TMB and ABTS oxidation played a significant role in the peroxidase reaction. The borophene QDs further proved to be successful for the colorimetric detection of antibiotics (oxytetracycline and tetracycline) using both TMB and ABTS peroxidase substrates. The limit of detection (LOD) for oxytetracycline and tetracycline was found to be 1.10 and 1.02 μM using TMB and 1.03 and 1.02 μM using ABTS chromogenic substrates, respectively. In addition, the fluorescence sensing of oxytetracycline and tetracycline over borophene QDs was also examined. The high fluorescence of borophene QDs (turn ON) was quenched (turn OFF) by oxytetracycline and tetracycline through the inner filter effect mechanism. The LOD of the fluorescence sensing of oxytetracycline and tetracycline was 1.14 and 1.08 μM, respectively. Interestingly, the borophene QDs could be used for the sensitive and selective colorimetric and fluorometric sensing of oxytetracycline and tetracycline after 120 days of storage. The synthesized borophene QDs with long-term stability and real sample analysis provide new insight as nanozymes with higher peroxidase mimetic and fluorescence performance and can be further exploited for medical diagnosis and environmental toxicants' detection.
فهرسة مساهمة: Keywords: borophene quantum dots; colorimetric; fluorometric; nanozyme; oxytetracycline; peroxidase mimic; tetracycline
المشرفين على المادة: EC 1.11.1.7 (Peroxidase)
28752-68-3 (2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid)
X20I9EN955 (Oxytetracycline)
0 (Chromogenic Compounds)
BBX060AN9V (Hydrogen Peroxide)
EC 1.11.1.- (Peroxidases)
0 (Anti-Bacterial Agents)
F8VB5M810T (Tetracycline)
059QF0KO0R (Water)
0 (Sulfonic Acids)
0 (Benzothiazoles)
تواريخ الأحداث: Date Created: 20240313 Date Completed: 20240329 Latest Revision: 20240329
رمز التحديث: 20240329
DOI: 10.1021/acsami.3c12108
PMID: 38478795
قاعدة البيانات: MEDLINE
الوصف
تدمد:1944-8252
DOI:10.1021/acsami.3c12108