دورية أكاديمية
Comparing Continuous Glucose Monitoring and Blood Glucose Monitoring in Adults With Inadequately Controlled, Insulin-Treated Type 2 Diabetes (Steno2tech Study): A 12-Month, Single-Center, Randomized Controlled Trial.
| العنوان: | Comparing Continuous Glucose Monitoring and Blood Glucose Monitoring in Adults With Inadequately Controlled, Insulin-Treated Type 2 Diabetes (Steno2tech Study): A 12-Month, Single-Center, Randomized Controlled Trial. |
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| المؤلفون: | Lind N; Department of Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Christensen MB; Department of Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark., Hansen DL; Department of Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark., Nørgaard K; Department of Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. |
| المصدر: | Diabetes care [Diabetes Care] 2024 May 01; Vol. 47 (5), pp. 881-889. |
| نوع المنشور: | Randomized Controlled Trial; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: American Diabetes Association Country of Publication: United States NLM ID: 7805975 Publication Model: Print Cited Medium: Internet ISSN: 1935-5548 (Electronic) Linking ISSN: 01495992 NLM ISO Abbreviation: Diabetes Care Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Alexandria Va : American Diabetes Association Original Publication: New York, American Diabetes Assn. |
| مواضيع طبية MeSH: | Diabetes Mellitus, Type 2*/drug therapy , Diabetes Mellitus, Type 1*, Adult ; Humans ; Male ; Female ; Insulin/therapeutic use ; Blood Glucose/metabolism ; Blood Glucose Self-Monitoring ; Glycated Hemoglobin ; Continuous Glucose Monitoring ; Insulin, Regular, Human/therapeutic use ; Hypoglycemic Agents/therapeutic use |
| مستخلص: | Objective: To compare the 12-month effects of continuous glucose monitoring (CGM) versus blood glucose monitoring (BGM) in adults with insulin-treated type 2 diabetes. Research Design and Methods: This is a single-center, parallel, open-label, randomized controlled trial including adults with inadequately controlled, insulin-treated type 2 diabetes from the outpatient clinic at Steno Diabetes Center Copenhagen, Denmark. Inclusion criteria were ≥18 years of age, insulin-treated type 2 diabetes, and HbA1c ≥7.5% (58 mmol/mol). Participants were randomly assigned (1:1) to 12 months of either CGM or BGM. All participants received a diabetes self-management education course and were followed by their usual health care providers. Primary outcome was between-group differences in change in time in range (TIR) 3.9-10.0 mmol/L, assessed at baseline, after 6 and 12 months by blinded CGM. The prespecified secondary outcomes were differences in change in several other glycemic, metabolic, and participant-reported outcomes. Results: The 76 participants had a median baseline HbA1c of 8.3 (7.8, 9.1)% (67 [62-76] mmol/mol), and 61.8% were male. Compared with BGM, CGM usage was associated with significantly greater improvements in TIR (between-group difference 15.2%, 95% CI 4.6; 25.9), HbA1c (-0.9%, -1.4; -0.3 [-9.4 mmol/mol, -15.2; -3.5]), total daily insulin dose (-10.6 units/day, -19.9; -1.3), weight (-3.3 kg, -5.5; -1.1), and BMI (-1.1 kg/m2, -1.8; -0.3) and greater self-rated diabetes-related health, well-being, satisfaction, and health behavior. Conclusions: In adults with inadequately controlled insulin-treated type 2 diabetes, the 12-month impact of CGM was superior to BGM in improving glucose control and other crucial health parameters. The findings support the use of CGM in the insulin-treated subgroup of type 2 diabetes. (© 2024 by the American Diabetes Association.) |
| المشرفين على المادة: | 0 (Insulin) 0 (Blood Glucose) 0 (Glycated Hemoglobin) 0 (Insulin, Regular, Human) 0 (Hypoglycemic Agents) |
| تواريخ الأحداث: | Date Created: 20240315 Date Completed: 20240422 Latest Revision: 20240422 |
| رمز التحديث: | 20240422 |
| DOI: | 10.2337/dc23-2194 |
| PMID: | 38489032 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1935-5548 |
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| DOI: | 10.2337/dc23-2194 |