دورية أكاديمية
Prevalence, outcomes and associated factors of SARS-CoV-2 infection in psoriasis patients of Southwest China: a cross-sectional survey.
العنوان: | Prevalence, outcomes and associated factors of SARS-CoV-2 infection in psoriasis patients of Southwest China: a cross-sectional survey. |
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المؤلفون: | Zou Y; Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China., Xu J; Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China., Chen AJ; Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China., Huang K; Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China., Zhu SM; Department of Dermatology, People's Hospital Affiliated of Chongqing Three Gorges Medical College, Chongqing, China., Li JJ; Department of Dermatology, Chongqing University Qianjiang Hospital, Chongqing, China., He J; Department of Dermatology, The People's Hospital of Kaizhou District, Chongqing, China., Li JZ; Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China., Xiong JX; Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China., Fan YK; Department of Dermatology, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, China., Liu C; Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China., Pan Y; Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China., Wang P; Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. wang_ping@hospital.cqmu.edu.cn. |
المصدر: | Scientific reports [Sci Rep] 2024 Mar 15; Vol. 14 (1), pp. 6331. Date of Electronic Publication: 2024 Mar 15. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: London : Nature Publishing Group, copyright 2011- |
مواضيع طبية MeSH: | COVID-19*/epidemiology , Psoriasis*/complications , Psoriasis*/epidemiology, Humans ; Cross-Sectional Studies ; Prevalence ; SARS-CoV-2 ; COVID-19 Vaccines ; China/epidemiology ; Disease Progression |
مستخلص: | In this study we aimed to investigate the prevalence of SARS-CoV-2 infection in psoriasis patients, and outcomes of SARS-CoV-2 infection and associated risk factors. A cross-sectional survey was conducted from February 2023 to March 2023. Information was obtained with online questionnaire about psoriasis patients on demographic characteristics, clinical characteristics, SARS-CoV-2 infection and outcomes, vaccination, and routine protection against COVID-19. Logistic regression analysis was used to explore risk factors with SARS-CoV-2 infection and exacerbation of psoriasis. A total of 613 participants were recruited. 516 (84.2%) were infected, and associated factors were sex, working status, routine protection against COVID-19, COVID-19 vaccination, impaired nail, infection exacerbate psoriasis, and severity of psoriasis. Among the patients infected with SARS-CoV-2, 30 (5.8%) required hospitalization, 122 (23.6%) had psoriasis exacerbation due to SARS-CoV-2 infection, and associated factors were subtype of psoriasis, discontinuation of psoriasis treatment during SARS-CoV-2 infection, response following COVID-19 vaccination, and severity of psoriasis. Booster dose vaccination contributed a low probability of COVID-19 sequelae. COVID-19 vaccine's effectiveness was unsatisfactory, while booster dose vaccination reduced the occurrence of COVID-19 sequelae in psoriasis patients of Southwest China. Patients treated with psoriasis shown to be safe, without a higher incidence of SARS-CoV-2 infection or COVID-19hospitalization compared to untreated patients. Stopping treatment during SARS-CoV-2 infection led to psoriasis exacerbation, so psoriasis treatment could be continued except severe adverse reaction. (© 2024. The Author(s).) |
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معلومات مُعتمدة: | 82103733 National Natural Science Foundation of China; 2022QNXM048 Joint project of Chongqing Health Commission and Science and Technology Bureau |
المشرفين على المادة: | 0 (COVID-19 Vaccines) |
تواريخ الأحداث: | Date Created: 20240316 Date Completed: 20240318 Latest Revision: 20240318 |
رمز التحديث: | 20240318 |
مُعرف محوري في PubMed: | PMC10943245 |
DOI: | 10.1038/s41598-024-54424-y |
PMID: | 38491005 |
قاعدة البيانات: | MEDLINE |
تدمد: | 2045-2322 |
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DOI: | 10.1038/s41598-024-54424-y |