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Astragali Radix: comprehensive review of its botany, phytochemistry, pharmacology and clinical application.

التفاصيل البيبلوغرافية
العنوان: Astragali Radix: comprehensive review of its botany, phytochemistry, pharmacology and clinical application.
المؤلفون: Liu YX; School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, 712046, Shaanxi, China., Song XM; School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, 712046, Shaanxi, China.; Shaanxi Key Laboratory of Research and Application of 'Taibai Qi Yao', Xianyang, 712046, Shaanxi, China., Dan LW; School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, 712046, Shaanxi, China., Tang JM; School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, 712046, Shaanxi, China., Jiang Y; School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, 712046, Shaanxi, China.; Shaanxi Key Laboratory of Research and Application of 'Taibai Qi Yao', Xianyang, 712046, Shaanxi, China., Deng C; School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, 712046, Shaanxi, China.; Shaanxi Key Laboratory of Research and Application of 'Taibai Qi Yao', Xianyang, 712046, Shaanxi, China., Zhang DD; School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, 712046, Shaanxi, China.; Shaanxi Key Laboratory of Research and Application of 'Taibai Qi Yao', Xianyang, 712046, Shaanxi, China., Li YZ; School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, 712046, Shaanxi, China. lyz1990yeah@163.com.; Shaanxi Key Laboratory of Research and Application of 'Taibai Qi Yao', Xianyang, 712046, Shaanxi, China. lyz1990yeah@163.com., Wang W; School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, 712046, Shaanxi, China. 2051003@sntcm.edu.cn.; Shaanxi Key Laboratory of Research and Application of 'Taibai Qi Yao', Xianyang, 712046, Shaanxi, China. 2051003@sntcm.edu.cn.
المصدر: Archives of pharmacal research [Arch Pharm Res] 2024 Mar; Vol. 47 (3), pp. 165-218. Date of Electronic Publication: 2024 Mar 16.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Pharmaceutical Society of Korea Country of Publication: Korea (South) NLM ID: 8000036 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1976-3786 (Electronic) Linking ISSN: 02536269 NLM ISO Abbreviation: Arch Pharm Res Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Seoul, Pharmaceutical Society of Korea.
مواضيع طبية MeSH: Astragalus Plant*/chemistry , Drugs, Chinese Herbal*/pharmacology , Drugs, Chinese Herbal*/therapeutic use , Drugs, Chinese Herbal*/chemistry , Saponins*/pharmacology , Botany*, Astragalus propinquus/chemistry
مستخلص: Astragali Radix (A. Radix) is the dried root of Astragalus membranaceus var. mongholicus (Bge) Hsiao or Astragalus membranaceus (Fisch.) Bge., belonging to the family Leguminosae, which is mainly distributed in China. A. Radix has been consumed as a tonic in China for more than 2000 years because of its medicinal effects of invigorating the spleen and replenishing qi. Currently, more than 400 natural compounds have been isolated and identified from A. Radix, mainly including saponins, flavonoids, phenylpropanoids, alkaloids, and others. Modern pharmacological studies have shown that A. Radix has anti-tumor, anti-inflammatory, immunomodulatory, anti-atherosclerotic, cardioprotective, anti-hypertensive, and anti-aging effects. It has been clinically used in the treatment of tumors, cardiovascular diseases, and cerebrovascular complications associated with diabetes with few side effects and high safety. This paper reviewed the progress of research on its chemical constituents, pharmacological effects, clinical applications, developing applications, and toxicology, which provides a basis for the better development and utilization of A. Radix.
(© 2024. The Pharmaceutical Society of Korea.)
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معلومات مُعتمدة: 2019ZDLSF04-03-02 Shaanxi Provincial Science and Technology Department Project; 82104368 National Natural Science Foundation of China; 22JK0344 Department of Education of Shaanxi Province
فهرسة مساهمة: Keywords: Astragali Radix (a. Radix); Chemical composition; Clinical application; Developing applications; Pharmacological effect
المشرفين على المادة: 0 (Drugs, Chinese Herbal)
0 (Saponins)
تواريخ الأحداث: Date Created: 20240317 Date Completed: 20240408 Latest Revision: 20240408
رمز التحديث: 20240408
DOI: 10.1007/s12272-024-01489-y
PMID: 38493280
قاعدة البيانات: MEDLINE
الوصف
تدمد:1976-3786
DOI:10.1007/s12272-024-01489-y