دورية أكاديمية
أعرض في EDS

Intracranial Epidermoid Cyst: A Volumetric Study of a Surgically Challenging Benign Lesion.

التفاصيل البيبلوغرافية
العنوان: Intracranial Epidermoid Cyst: A Volumetric Study of a Surgically Challenging Benign Lesion.
المؤلفون: Kiss-Bodolay D; Department of Neurosurgery, Geneva University Hospital, Geneva, Switzerland; Faculty of Medicine, University of Geneva, Geneva, Switzerland. Electronic address: daniel.kiss.b@gmail.com., Hautmann X; Department of Neurosurgery, University Medical Center Göttingen, Göttingen, Germany., Lee KS; Department of Basic Neurosciences and the Center for Neuroscience, Faculty of Medicine, University of Geneva, Geneva, Switzerland., Rohde V; Department of Neurosurgery, University Medical Center Göttingen, Göttingen, Germany., Schaller K; Department of Neurosurgery, Geneva University Hospital, Geneva, Switzerland; Faculty of Medicine, University of Geneva, Geneva, Switzerland.
المصدر: World neurosurgery [World Neurosurg] 2024 May; Vol. 185, pp. e1129-e1135. Date of Electronic Publication: 2024 Mar 15.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 101528275 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-8769 (Electronic) Linking ISSN: 18788750 NLM ISO Abbreviation: World Neurosurg Subsets: MEDLINE
أسماء مطبوعة: Original Publication: New York : Elsevier
مواضيع طبية MeSH: Epidermal Cyst*/surgery , Epidermal Cyst*/diagnostic imaging , Magnetic Resonance Imaging*, Humans ; Male ; Female ; Adult ; Middle Aged ; Retrospective Studies ; Young Adult ; Aged ; Neurosurgical Procedures/methods ; Adolescent ; Brain Diseases/surgery ; Brain Diseases/diagnostic imaging ; Child ; Microsurgery/methods
مستخلص: Background: Intracranial epidermoid cysts are rare, benign tumors. Nevertheless, the microsurgical removal of these cysts is challenging. This is due to their capacity to adhere to the neurovascular tissue, as well as the associated difficulties in microsurgically peeling off their capsular wall hidden in dead angles. To better understand the rate of recurrence after surgical intervention, we have performed preoperative and postoperative volumetric analysis of epidermoid cysts, allowing the estimation of their growth rate after resection.
Methods: Imaging data from 22 patients diagnosed and surgically treated for an intracranial epidermoid cyst between 2000 and 2022 were retrospectively collected from 2 European neurosurgical centers with microsurgical expertise. Volumetric analysis was performed on magnetic resonance imaging data.
Results: Average cyst volume at diagnosis, before any surgery, measured in 12 patients was 28,877.6 ± 10,250.4 mm 3 (standard error of the mean [SEM]). Estimated growth rate of incompletely resected epidermoids after surgery was 1,630.05 mm 3 ± 729.95 (SEM). Assuming linear growth dynamics and normalizing to postoperative residual volume, the average postoperative growth rate corresponded to 61.5% ± 34.3% (SEM) of the postoperative residual volume per year. We observed signs of recurrence during a radiologic follow-up period of 6.0 ± 2.8 years (standard deviation) in more than 50% of our patients.
Conclusions: Due to their slow-growing nature, epidermoid cysts can often reach a complex multicompartmental size before resection, even in young patients, thus requiring complex approaches with challenging capsular resection, which implies a high risk of nerve and vascular injury per se. Tumor recurrence may be predicted on the basis of postoperative volumetry.
(Copyright © 2024 The Author(s). Published by Elsevier Inc. All rights reserved.)
فهرسة مساهمة: Keywords: EOR; Intracranial epidermoid cyst; Microneurosurgery; Recurrence; Volumetric study
تواريخ الأحداث: Date Created: 20240317 Date Completed: 20240514 Latest Revision: 20240702
رمز التحديث: 20240702
DOI: 10.1016/j.wneu.2024.03.035
PMID: 38493891
قاعدة البيانات: MEDLINE
الوصف
تدمد:1878-8769
DOI:10.1016/j.wneu.2024.03.035