دورية أكاديمية
Surgical complications of vagus nerve stimulation surgery: A 14-years single-center experience.
| العنوان: | Surgical complications of vagus nerve stimulation surgery: A 14-years single-center experience. |
|---|---|
| المؤلفون: | van Schooten J; Faculty of Health, Medicine and Life Sciences, Maastricht University, the Netherlands.; Department of Neurosurgery, Maastricht University Medical Center, the Netherlands., Smeets J; Faculty of Health, Medicine and Life Sciences, Maastricht University, the Netherlands.; Department of Neurosurgery, Maastricht University Medical Center, the Netherlands., van Kuijk SM; Department of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Center, the Netherlands., Klinkenberg S; School for Mental Health & Neuroscience, Maastricht University, the Netherlands.; Department of Neurology, Maastricht University Medical Center, the Netherlands.; ACE: Academic Center for Epileptology, Maastricht University Medical Center and Kempenhaeghe, Maastricht, Heeze, the Netherlands., Schijns OEMG; Department of Neurosurgery, Maastricht University Medical Center, the Netherlands.; School for Mental Health & Neuroscience, Maastricht University, the Netherlands.; ACE: Academic Center for Epileptology, Maastricht University Medical Center and Kempenhaeghe, Maastricht, Heeze, the Netherlands., Nelissen J; Department of Neurosurgery, Maastricht University Medical Center, the Netherlands.; ACE: Academic Center for Epileptology, Maastricht University Medical Center and Kempenhaeghe, Maastricht, Heeze, the Netherlands., Wagner LGL; School for Mental Health & Neuroscience, Maastricht University, the Netherlands.; ACE: Academic Center for Epileptology, Maastricht University Medical Center and Kempenhaeghe, Maastricht, Heeze, the Netherlands., Rouhl RPW; School for Mental Health & Neuroscience, Maastricht University, the Netherlands.; Department of Neurology, Maastricht University Medical Center, the Netherlands.; ACE: Academic Center for Epileptology, Maastricht University Medical Center and Kempenhaeghe, Maastricht, Heeze, the Netherlands., Majoie MHJM; School for Mental Health & Neuroscience, Maastricht University, the Netherlands.; Department of Neurology, Maastricht University Medical Center, the Netherlands.; ACE: Academic Center for Epileptology, Maastricht University Medical Center and Kempenhaeghe, Maastricht, Heeze, the Netherlands., Rijkers K; Department of Neurosurgery, Maastricht University Medical Center, the Netherlands.; School for Mental Health & Neuroscience, Maastricht University, the Netherlands.; ACE: Academic Center for Epileptology, Maastricht University Medical Center and Kempenhaeghe, Maastricht, Heeze, the Netherlands. |
| المصدر: | Brain & spine [Brain Spine] 2023 Dec 14; Vol. 4, pp. 102733. Date of Electronic Publication: 2023 Dec 14 (Print Publication: 2024). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 9918470888906676 Publication Model: eCollection Cited Medium: Internet ISSN: 2772-5294 (Electronic) Linking ISSN: 27725294 NLM ISO Abbreviation: Brain Spine Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: [Amsterdam] : Elsevier B.V., [2021]- |
| مستخلص: | Introduction: Vagus nerve stimulation (VNS) is the most frequently used neuromodulation treatment for Drug-Resistant Epilepsy (DRE) patients. Complications of VNS surgery include surgical site infection and unilateral vocal cord paresis. Complication rates vary across studies. Research Question: What is the safety profile of VNS related surgeries? Materials and Methods: Retrospective cohort study using patient files of DRE-patients who had undergone primary implantation of a VNS-system, replacement of the VNS pulse generator, replacement of the lead, replacement of both pulse generator and lead, or VNS removal surgery in the Maastricht UMC+. Multiple Imputation was used for missing data. Univariable and multivariable logistic regression analysis were performed to analyze possible risk factors, in case of a small sample size, an independent-samples t -test and Fisher's exact test or Pearson's X 2 -test were used. The complication rate was calculated as percentage. Results: This study included a total of 606 VNS surgical procedures, leading to 67 complications of which 3 permanent complications. Complication rate after primary implantation was 13.4%; 2,5% for pulse generator replacement; 21.4% for lead revision and 27.3% for complete VNS removal. No statistically significant results were found when analyzing the results of adults and children <18 years separately. Discussion and Conclusion: Complication rates of VNS-related surgeries in our own institutional series are low and comparable to previously reported series. VNS surgery is a relatively safe procedure. The complication rate differs per type of surgery and mean surgery duration was longer for patients with complications after lead revision surgery compared to patients without complications. Competing Interests: None declared. (© 2023 The Authors.) |
| References: | Laryngoscope. 2015 Jun;125(6):1352-5. (PMID: 25429912) Neurosurgery. 2010 Dec;67(2 Suppl Operative):489-94. (PMID: 21099577) Eur Arch Otorhinolaryngol. 2021 Oct;278(10):3891-3899. (PMID: 34196736) Epilepsy Behav Rep. 2021 Mar 26;15:100437. (PMID: 33912822) Pediatr Neurosurg. 2002 Mar;36(3):164-6. (PMID: 11919454) Acta Neurol Belg. 1999 Dec;99(4):275-80. (PMID: 10674145) Neurology. 1993 Jul;43(7):1338-45. (PMID: 8327135) Neurosurg Clin N Am. 2019 Apr;30(2):219-230. (PMID: 30898273) Infect Dis Clin North Am. 2011 Mar;25(1):135-53. (PMID: 21315998) Am J Surg. 2005 Apr;189(4):395-404. (PMID: 15820449) J Neurosurg Pediatr. 2016 Jul;18(1):97-104. (PMID: 27015521) Epilepsia. 2017 Apr;58 Suppl 1:85-90. (PMID: 28386925) Int J Environ Res Public Health. 2020 Aug 24;17(17):. (PMID: 32847092) Eur J Paediatr Neurol. 2016 Jul;20(4):678-83. (PMID: 27056279) Seizure. 2013 Dec;22(10):827-33. (PMID: 23867218) Neurosurgery. 2016 Jan;78(1):42-6. (PMID: 26678088) Acta Neurochir (Wien). 2015 Nov;157(11):1917-24. (PMID: 26335753) |
| فهرسة مساهمة: | Keywords: Epilepsy; Surgical complications; Vagus nerve stimulation |
| تواريخ الأحداث: | Date Created: 20240321 Latest Revision: 20240322 |
| رمز التحديث: | 20240322 |
| مُعرف محوري في PubMed: | PMC10951712 |
| DOI: | 10.1016/j.bas.2023.102733 |
| PMID: | 38510607 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 2772-5294 |
|---|---|
| DOI: | 10.1016/j.bas.2023.102733 |