دورية أكاديمية
The impact of stress on the behavior of C57BL/6 mice with liver injury: a comparative study.
العنوان: | The impact of stress on the behavior of C57BL/6 mice with liver injury: a comparative study. |
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المؤلفون: | Mușat MI; U.M.F. Doctoral School Craiova, University of Medicine and Pharmacy of Craiova, Craiova, Romania.; Experimental Research Centre for Normal and Pathological Aging, University of Medicine and Pharmacy of Craiova, Craiova, Romania., Mitran SI; Experimental Research Centre for Normal and Pathological Aging, University of Medicine and Pharmacy of Craiova, Craiova, Romania.; Department of Physiology, University of Medicine and Pharmacy of Craiova, Craiova, Romania., Udriștoiu I; Department of Psychiatry, University of Medicine and Pharmacy, Craiova, Romania., Albu CV; Department of Neurology, University of Medicine and Pharmacy, Craiova, Romania., Cătălin B; Experimental Research Centre for Normal and Pathological Aging, University of Medicine and Pharmacy of Craiova, Craiova, Romania.; Department of Physiology, University of Medicine and Pharmacy of Craiova, Craiova, Romania. |
المصدر: | Frontiers in behavioral neuroscience [Front Behav Neurosci] 2024 Mar 06; Vol. 18, pp. 1358964. Date of Electronic Publication: 2024 Mar 06 (Print Publication: 2024). |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101477952 Publication Model: eCollection Cited Medium: Print ISSN: 1662-5153 (Print) Linking ISSN: 16625153 NLM ISO Abbreviation: Front Behav Neurosci Subsets: PubMed not MEDLINE |
أسماء مطبوعة: | Original Publication: Lausanne, Switzerland : Frontiers Research Foundation, 2007- |
مستخلص: | Introduction: Depressive-like behavior has been shown to be associated with liver damage. This study aimed to evaluate the impact of three different models of depression on the behavior of mice with liver injury. Methods: During the 4 weeks of methionine/choline deficiency diet (MCD), adult C57BL/6 mice were randomly divided into four groups: MCD (no stress protocol, n = 6), chronic unpredictable mild stress (CUMS, n = 9), acute and repeated forced swim stress [aFSS ( n = 9) and rFSS ( n = 9)]. Results: All depression protocols induced increased anhedonia and anxiety-like behavior compared to baseline and had no impact on the severity of liver damage, according to ultrasonography. However, different protocols evoked different overall behavior patterns. After the depressive-like behavior induction protocols, animals subjected to aFSS did not exhibit anxiety-like behavior differences compared to MCD animals, while mice subjected to CUMS showed additional weight loss compared to FSS animals. All tested protocols for inducing depressive-like behavior decreased the short-term memory of mice with liver damage, as assessed by the novel object recognition test (NORT). Discussion: Our results show that the use of all protocols seems to generate different levels of anxiety-like behavior, but only the depressive-like behavior induction procedures associate additional anhedonia and memory impairment in mice with liver injury. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2024 Mușat, Mitran, Udriștoiu, Albu and Cătălin.) |
References: | Prog Neuropsychopharmacol Biol Psychiatry. 2020 Mar 2;98:109812. (PMID: 31707090) Sci Rep. 2020 Sep 23;10(1):15532. (PMID: 32968123) Hum Exp Toxicol. 2014 Jul;33(7):701-9. (PMID: 24130212) ACS Omega. 2020 Aug 12;5(33):20800-20809. (PMID: 32875214) Eur J Pain. 2019 Feb;23(2):285-306. (PMID: 30098102) Can J Psychiatry. 2003 May;48(4):250-7. (PMID: 12776392) Curr Opin Behav Sci. 2018 Oct;23:143-149. (PMID: 30560152) Sci Rep. 2019 Nov 22;9(1):17403. (PMID: 31758000) Transl Psychiatry. 2022 Sep 23;12(1):404. (PMID: 36151082) Sci Rep. 2023 Oct 12;13(1):17297. (PMID: 37828065) Eur J Pharmacol. 2001 Mar;415(2-3):197-201. (PMID: 11274999) Brain Behav Immun. 2020 Jul;87:556-567. (PMID: 32058038) Brain Behav Immun. 2019 Oct;81:361-373. (PMID: 31255681) Brain Behav Immun. 2021 Jan;91:24-47. (PMID: 32755644) Gut Liver. 2021 Mar 15;15(2):206-216. (PMID: 32921636) Epidemiol Psychiatr Sci. 2021 Mar 12;30:e23. (PMID: 33706839) J Lipid Res. 2008 May;49(5):1068-76. (PMID: 18227531) Hepatol Commun. 2020 Jun 22;4(9):1293-1301. (PMID: 32923833) Int J Mol Sci. 2023 Sep 27;24(19):. (PMID: 37834073) Lab Anim Res. 2017 Jun;33(2):157-164. (PMID: 28747982) Behav Brain Res. 2006 Nov 25;175(1):43-50. (PMID: 17023061) J Neurosurg. 2018 Nov 1;129(5):1286-1294. (PMID: 29372883) J Affect Disord. 2018 Feb;227:126-135. (PMID: 29055260) Psychopharmacology (Berl). 2015 Dec;232(23):4325-35. (PMID: 26337614) Biol Psychiatry. 2014 Oct 1;76(7):542-9. (PMID: 24576687) Neuroreport. 2022 Apr 6;33(6):272-282. (PMID: 35383656) Science. 2019 May 31;364(6443):825-826. (PMID: 31147505) Neuropsychopharmacology. 2018 Apr;43(5):931-933. (PMID: 29210364) J Vis Exp. 2018 Oct 24;(140):. (PMID: 30417885) Prog Neuropsychopharmacol Biol Psychiatry. 2013 Jan 10;40:213-20. (PMID: 23367508) Life (Basel). 2022 Nov 04;12(11):. (PMID: 36362945) Int J Neuropsychopharmacol. 2015 Apr 21;18(10):pyv045. (PMID: 25899065) Curr Protoc. 2021 Aug;1(8):e208. (PMID: 34406704) Neuropharmacology. 2021 Oct 15;198:108782. (PMID: 34492286) Behav Sci (Basel). 2022 May 29;12(6):. (PMID: 35735376) Neuropsychiatr Dis Treat. 2021 Apr 06;17:1001-1019. (PMID: 33854318) Brain Sci. 2021 Dec 09;11(12):. (PMID: 34942925) Trends Neurosci. 2015 Oct;38(10):637-658. (PMID: 26442697) J Vis Exp. 2015 Mar 02;(97):. (PMID: 25867960) Neuroscience. 2000;95(1):293-307. (PMID: 10619486) Lab Anim (NY). 2017 Mar 22;46(4):157-161. (PMID: 28328884) Toxicol In Vitro. 2017 Oct;44:154-163. (PMID: 28712878) Horm Behav. 2003 May;43(5):561-7. (PMID: 12799173) Int Immunopharmacol. 2022 Aug;109:108788. (PMID: 35504201) Neurobiol Stress. 2023 Aug 26;26:100567. (PMID: 37706061) Eur Neuropsychopharmacol. 2021 Sep;50:55-63. (PMID: 33971385) J Psychosom Res. 2002 Oct;53(4):897-902. (PMID: 12377300) Front Mol Neurosci. 2023 Jul 04;16:1146109. (PMID: 37470056) Toxicol Rep. 2022 Mar 29;9:588-596. (PMID: 35392157) Nature. 2014 May 15;509(7500):282-3. (PMID: 24834516) Arch Toxicol. 2020 Jul;94(7):2401-2411. (PMID: 32372212) Quant Imaging Med Surg. 2019 Apr;9(4):546-551. (PMID: 31143646) Front Behav Neurosci. 2020 Aug 27;14:140. (PMID: 33192355) Int J Clin Exp Pathol. 2013 Nov 15;6(12):2683-96. (PMID: 24294355) J Cereb Blood Flow Metab. 2021 Sep;41(9):2162-2173. (PMID: 33641516) PLoS One. 2014 Dec 01;9(12):e111065. (PMID: 25436462) JAMA. 2017 Apr 18;317(15):1517. (PMID: 28418490) J Neurosci. 2003 Jul 2;23(13):5674-83. (PMID: 12843270) World J Gastroenterol. 2014 Jun 14;20(22):6821-5. (PMID: 24944472) Nat Rev Gastroenterol Hepatol. 2018 Aug;15(8):461-478. (PMID: 29844588) Genes Brain Behav. 2007 Mar;6(2):192-200. (PMID: 16827921) Brain Behav. 2018 Jun;8(6):e00964. (PMID: 30106230) Nat Neurosci. 2005 Jun;8(6):797-804. (PMID: 15895085) Biotech Histochem. 2017;92(6):390-401. (PMID: 28800278) J Psychiatr Res. 2008 Jan;42(2):151-7. (PMID: 17174336) Brain Res Brain Res Protoc. 2005 Dec;16(1-3):70-8. (PMID: 16338640) Hepatology. 2016 Dec;64(6):1969-1977. (PMID: 27301913) Prog Neuropsychopharmacol Biol Psychiatry. 2021 Jul 13;109:110239. (PMID: 33400944) Cell Tissue Res. 2016 Nov;366(2):271-284. (PMID: 27481508) J Gerontol A Biol Sci Med Sci. 2016 Nov;71(11):1407-1414. (PMID: 27535963) Lab Anim. 2004 Apr;38(2):178-88. (PMID: 15070458) Diabetol Metab Syndr. 2018 Jan 24;10:4. (PMID: 29410708) Neurosci Lett. 2020 Jan 23;718:134750. (PMID: 31926175) Brain Res Brain Res Protoc. 2004 Aug;13(3):151-8. (PMID: 15296852) Behav Brain Res. 2010 Nov 12;213(1):94-102. (PMID: 20438768) |
فهرسة مساهمة: | Keywords: CUMS; FSS; NAFLD; anxiety; depression |
تواريخ الأحداث: | Date Created: 20240321 Latest Revision: 20240322 |
رمز التحديث: | 20240322 |
مُعرف محوري في PubMed: | PMC10950904 |
DOI: | 10.3389/fnbeh.2024.1358964 |
PMID: | 38510829 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1662-5153 |
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DOI: | 10.3389/fnbeh.2024.1358964 |