دورية أكاديمية
أعرض في EDS

Image-based non-invasive assessment of suction blister wounds for clinical safety and efficacy.

التفاصيل البيبلوغرافية
العنوان: Image-based non-invasive assessment of suction blister wounds for clinical safety and efficacy.
المؤلفون: Wallblom K; Division of Dermatology and Venereology, Department of Clinical Sciences, Lund University, Lund, Sweden.; Department of Dermatology, Skane University Hospital, Lund, Sweden., Lundgren S; Division of Dermatology and Venereology, Department of Clinical Sciences, Lund University, Lund, Sweden.; Department of Dermatology, Skane University Hospital, Lund, Sweden., Saleh K; Division of Dermatology and Venereology, Department of Clinical Sciences, Lund University, Lund, Sweden.; Department of Dermatology, Skane University Hospital, Lund, Sweden., Schmidtchen A; Division of Dermatology and Venereology, Department of Clinical Sciences, Lund University, Lund, Sweden.; Department of Dermatology, Skane University Hospital, Lund, Sweden., Puthia M; Division of Dermatology and Venereology, Department of Clinical Sciences, Lund University, Lund, Sweden.
المصدر: Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society [Wound Repair Regen] 2024 Jul-Aug; Vol. 32 (4), pp. 343-359. Date of Electronic Publication: 2024 Mar 21.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Blackwell Science Country of Publication: United States NLM ID: 9310939 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-475X (Electronic) Linking ISSN: 10671927 NLM ISO Abbreviation: Wound Repair Regen Subsets: MEDLINE
أسماء مطبوعة: Publication: <2010-> : Malden, MA : Blackwell Science
Original Publication: St. Louis, MO : Mosby, c1993-
مواضيع طبية MeSH: Wound Healing*/physiology , Photography*/methods , Blister*, Humans ; Suction/methods ; Erythema ; Female ; Male ; Bandages ; Exudates and Transudates ; Image Processing, Computer-Assisted/methods
مستخلص: Recognising the need for objective imaging-based technologies to assess wound healing in clinical studies, the suction blister wound model offers an easily accessible wound model that creates reproducible epidermal wounds that heal without scarring. This study provides a comprehensive methodology for implementing and evaluating photography-based imaging techniques utilising the suction blister wound model. Our method encompasses a protocol for capturing consistent, high-quality photographs and procedures for quantifying these images via a visual wound healing score and a computer-assisted colour analysis of wound exudation and wound redness. We employed this methodology on 16 suction blister wounds used as controls in a clinical phase-1 trial. Our method enabled us to discern and quantify subtle differences between individual wounds concerning healing progress, erythema and wound exudation. The wound healing score exhibited a high inter-rater agreement. There was a robust correlation between the spectrophotometer-measured erythema index and photography-based wound redness, as well as between dressing protein content and photography-based dressing yellowness. In conclusion, this study equips researchers conducting clinical wound studies with reproducible methods that may support future wound research and aid in the development of new treatments.
(© 2024 The Authors. Wound Repair and Regeneration published by Wiley Periodicals LLC on behalf of The Wound Healing Society.)
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معلومات مُعتمدة: Crafoordska Stiftelsen; 2020-02016 Vetenskapsrådet; Alfred Österlunds Stiftelse; HudFonden; Swedish Government Funds for Clinical Research (ALF); Xinnate AB
فهرسة مساهمة: Keywords: clinical photography; clinical studies; clinical trial; imaging; wound healing
تواريخ الأحداث: Date Created: 20240321 Date Completed: 20240710 Latest Revision: 20240710
رمز التحديث: 20240710
DOI: 10.1111/wrr.13172
PMID: 38511666
قاعدة البيانات: MEDLINE
الوصف
تدمد:1524-475X
DOI:10.1111/wrr.13172