دورية أكاديمية
أعرض في EDS

Onychocytic Matricoma: A Clinical, Dermoscopic, and Pathological Analysis of 14 Cases.

التفاصيل البيبلوغرافية
العنوان: Onychocytic Matricoma: A Clinical, Dermoscopic, and Pathological Analysis of 14 Cases.
المؤلفون: Perrin C; Dermatologists, Laboratoire Central d'Anatomie Pathologique, Nice University Hospital, University of Côte d'Azur (UCA), Nice, France.; Nail's Dermatology Consultations, Cannes, France., Coutts M; Department of Cellular Pathology, Maidstone Hospital, Kent, United Kingdom; and., Boukari F; Department of Dermatology, Nice University Hospital, University of Côte d'Azur (UCA), Nice, France., Ambrosetti D; Dermatologists, Laboratoire Central d'Anatomie Pathologique, Nice University Hospital, University of Côte d'Azur (UCA), Nice, France.
المصدر: The American Journal of dermatopathology [Am J Dermatopathol] 2024 May 01; Vol. 46 (5), pp. 259-270. Date of Electronic Publication: 2024 Mar 19.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 7911005 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1533-0311 (Electronic) Linking ISSN: 01931091 NLM ISO Abbreviation: Am J Dermatopathol Subsets: MEDLINE
أسماء مطبوعة: Publication: Hagerstown, MD : Lippincott Williams & Wilkins
Original Publication: New York, Masson Publishing USA.
مواضيع طبية MeSH: Skin Neoplasms*/pathology , Nail Diseases*/diagnosis , Nail Diseases*/pathology , Acanthoma*/pathology , Nails, Malformed*/pathology , Carcinoma, Squamous Cell*/diagnosis, Humans ; Retrospective Studies ; Diagnosis, Differential ; Dermoscopy
مستخلص: Abstract: Onychocytic matricoma (OCM) is a benign neoplasm of the nail matrix. Only 18 cases of this tumor have been reported in the literature to date. We retrospectively analyzed the clinical features of 14 patients with OCM. The most common clinical feature was longitudinal xanthopachyonychia (n = 9), followed by longitudinal leukopachyonychia (=3) and longitudinal pachymelanonychia (n = 2). The most common clinical findings identified following dermoscopy and analysis at high magnification of classical photographs were free-edge thickening of the nail plate without pitting (n = 14), longitudinal ridging (n = 7), round white clods (n = 7), white dots (n = 7), and filiform hemorrhages (n = 7), followed by oval and linear white clods (n = 5), fuzzy lateral border (n = 5), and red-purple blood clods (n = 3). Nail clipping histopathology showed a thickened nail plate with multiple, small, round-to-oval spaces. The tumor expressed immunopositivity for LEF-1. Dermoscopy of the nail plate and nail clipping histology provides useful information with regards to the differential diagnosis with subungual squamous cell carcinoma and nail melanoma. Ex vivo-in vivo correlation facilitates a better dermoscopic assessment of this unique underrecognized disease. However, the differential diagnosis between OCM and onychocytic carcinoma requires biopsy of the tumor. LEF-1 as an onychogenic marker can be used to resolve the differential diagnosis between OCM and subungual longitudinal acanthoma/seborrheic keratosis.
(Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc.)
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تواريخ الأحداث: Date Created: 20240321 Date Completed: 20240422 Latest Revision: 20240429
رمز التحديث: 20240429
مُعرف محوري في PubMed: PMC11027982
DOI: 10.1097/DAD.0000000000002674
PMID: 38513115
قاعدة البيانات: MEDLINE
الوصف
تدمد:1533-0311
DOI:10.1097/DAD.0000000000002674