دورية أكاديمية
أعرض في EDS

ELLIPSOID ZONE RECOVERY IN MACULAR TELANGIECTASIA TYPE 2.

التفاصيل البيبلوغرافية
العنوان: ELLIPSOID ZONE RECOVERY IN MACULAR TELANGIECTASIA TYPE 2.
المؤلفون: Goerdt L; Department of Ophthalmology, University Hospital Bonn, Bonn, Germany ; and., Raming K; Department of Ophthalmology, University Hospital Bonn, Bonn, Germany ; and., Rodriguez Garcia JL; Department of Ophthalmology, University Hospital Bonn, Bonn, Germany ; and., Pfau K; Department of Ophthalmology, University Hospital Bonn, Bonn, Germany ; and.; Department of Ophthalmology, University Hospital Basel, Basel, Switzerland ., Holz FG; Department of Ophthalmology, University Hospital Bonn, Bonn, Germany ; and., Herrmann P; Department of Ophthalmology, University Hospital Bonn, Bonn, Germany ; and.
المصدر: Retina (Philadelphia, Pa.) [Retina] 2024 Aug 01; Vol. 44 (8), pp. 1413-1421.
نوع المنشور: Journal Article; Observational Study
اللغة: English
بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 8309919 Publication Model: Print Cited Medium: Internet ISSN: 1539-2864 (Electronic) Linking ISSN: 0275004X NLM ISO Abbreviation: Retina Subsets: MEDLINE
أسماء مطبوعة: Publication: Hagerstown, MD : Lippincott Williams & Wilkins
Original Publication: Philadelphia : Lippincott, [1981?-
مواضيع طبية MeSH: Tomography, Optical Coherence*/methods , Visual Acuity*/physiology , Retinal Telangiectasis*/diagnosis , Retinal Telangiectasis*/physiopathology , Retinal Telangiectasis*/classification , Fluorescein Angiography*/methods, Humans ; Female ; Male ; Aged ; Middle Aged ; Follow-Up Studies ; Macula Lutea/diagnostic imaging ; Macula Lutea/pathology ; Retrospective Studies ; Recovery of Function/physiology ; Fundus Oculi
مستخلص: Purpose: To describe imaging features of macular telangiectasia type 2 eyes experiencing ellipsoid zone (EZ) recovery.
Methods: Macular telangiectasia type 2 patients with EZ recovery were identified from the Natural History and Observational Registry study and underwent retinal imaging including optical coherence tomography and fundus photography. Eyes were graded according to the classification system by Gass and Blodi, the EZ-loss area was measured, and optical coherence tomography parameters were assessed by two independent readers. Parameters were analyzed for their presence before EZ recovery.
Results: Twenty-four eyes of 21 patients (12 female, 57.12%; mean age 68 ± 8.54 years) were included in this study and followed for 21.25 months ± 12.79 months. At baseline, mean EZ-loss area was 0.036 mm 2 ± 0.028 mm 2 and 0.01 mm 2 ± 0.013 mm 2 at follow-up ( P < 0.001). A persisting external limiting membrane overlaying the EZ-loss was detected in 16 cases (66%), and hyperreflective changes in the outer retina were present in 18 cases (75%). Best-corrected visual acuity was 0.23 (20/32) ± 0.33 logMAR at baseline and 0.34 (20/40) ± 0.34 logMAR at follow-up ( P = 0.3).
Conclusion: Distinct optical coherence tomography features precede ellipsoid zone recovery in macular telangiectasia type 2 and warrant further studies investigating implications for patient care and clinical trial interpretation.
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معلومات مُعتمدة: Lowy Medical Research Institute
تواريخ الأحداث: Date Created: 20240321 Date Completed: 20240725 Latest Revision: 20240725
رمز التحديث: 20240726
DOI: 10.1097/IAE.0000000000004108
PMID: 38513243
قاعدة البيانات: MEDLINE
الوصف
تدمد:1539-2864
DOI:10.1097/IAE.0000000000004108