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Significance of lung nodules detected on chest CT among adult Aboriginal Australians - a retrospective descriptive study.

التفاصيل البيبلوغرافية
العنوان: Significance of lung nodules detected on chest CT among adult Aboriginal Australians - a retrospective descriptive study.
المؤلفون: Ng LY; Department of Respiratory and Sleep Medicine, Royal Darwin Hospital, Darwin, Northern Territory, Australia.; College of Medicine and Public Health, Flinders University, Darwin, Northern Territory, Australia., Howarth TP; Darwin Respiratory and Sleep Health, Darwin Private Hospital, Darwin, Northern Territory, Australia.; Department of Technical Physics, University of Eastern Finland, Kuopio, Finland.; Diagnostic Imaging Centre, Kuopio University Hospital, Kuopio, Northern Savo, Finland., Doss AX; Department of Medical Imaging, Royal Darwin Hospital, Darwin, Northern Territory, Australia.; Curtin Medical School, Bentley, Western Australia, Australia., Charakidis M; Department of Medical Oncology, Royal Darwin Hospital, Darwin, Northern Territory, Australia., Karanth NV; Department of Medical Oncology, Royal Darwin Hospital, Darwin, Northern Territory, Australia., Mo L; Department of Respiratory and Sleep Medicine, Royal Darwin Hospital, Darwin, Northern Territory, Australia.; College of Medicine and Public Health, Flinders University, Darwin, Northern Territory, Australia., Heraganahally SS; Department of Respiratory and Sleep Medicine, Royal Darwin Hospital, Darwin, Northern Territory, Australia.; College of Medicine and Public Health, Flinders University, Darwin, Northern Territory, Australia.; Darwin Respiratory and Sleep Health, Darwin Private Hospital, Darwin, Northern Territory, Australia.
المصدر: Journal of medical radiation sciences [J Med Radiat Sci] 2024 Mar 22. Date of Electronic Publication: 2024 Mar 22.
Publication Model: Ahead of Print
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Wiley Publishing Asia Pty Ltd Country of Publication: United States NLM ID: 101620352 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2051-3909 (Electronic) Linking ISSN: 20513895 NLM ISO Abbreviation: J Med Radiat Sci Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [Malden, MA] : Wiley Publishing Asia Pty Ltd, [2013]-
مستخلص: Introduction: There are limited data on chest computed tomography (CT) findings in the assessment of lung nodules among adult Aboriginal Australians. In this retrospective study, we assessed lung nodules among a group of adult Aboriginal Australians in the Northern Territory of Australia.
Methods: Patients who underwent at least two chest CT scans between 2012 and 2020 among those referred to undergo lung function testing (spirometry) were included. Chest CT scans were assessed for the number, location, size and morphological characteristics of lung nodules.
Results: Of the 402 chest CTs assessed, 75 patients (18.7%) had lung nodules, and 57 patients were included in the final analysis with at least two CT scans available for assessment over a median follow-up of 87 weeks. Most patients (68%) were women, with a median age of 58 years and smoking history in 83%. The majority recorded only a single nodule 43 (74%). Six patients (10%) were diagnosed with malignancy, five with primary lung cancer and one with metastatic thyroid cancer. Of the 51 (90%) patients assessed to be benign, 64 nodules were identified, of which 25 (39%) resolved, 38 (59%) remained stable and one (1.8%) enlarged on follow-up. Nodules among patients with malignancy were typically initially larger and enlarged over time, had spiculated margins and were solid, showing no specific lobar predilection.
Conclusions: Most lung nodules in Aboriginal Australians are likely to be benign. However, a proportion could be malignant. Further prospective studies are required for prognostication and monitoring of lung nodules in this population.
(© 2024 The Authors. Journal of Medical Radiation Sciences published by John Wiley & Sons Australia, Ltd on behalf of Australian Society of Medical Imaging and Radiation Therapy and New Zealand Institute of Medical Radiation Technology.)
References: Howarth TP, Jersmann H, Majoni S, et al. The ‘ABC’ of respiratory disorders among adult Indigenous people: Asthma, bronchiectasis and COPD among Aboriginal Australians – A systematic review. BMJ Open Respir Res 2023; 10: e001738.
Howarth T, Heraganahally SS, Heraganahally SS. Bronchiectasis among adult First Nations Indigenous people – A scoping review. Curr Respir Med Rev 2023; 19: 36–51.
Cancer in Australia. Australian Institute of Health and Welfare. AIHW, Cabberra, 2019. Available from: https://www.aihw.gov.au.
Basnayake TL, Valery PC, Carson P, De Ieso PB. Treatment and outcomes for indigenous and non‐indigenous lung cancer patients in the Top End of the Northern Territory. Intern Med J 2021; 51: 1081–1091.
Condon JR, Zhang X, Dempsey K, Garling L, Guthridge S. Trends in cancer incidence and survival for Indigenous and non‐Indigenous people in the Northern Territory. Med J Aust 2016; 205: 454–458.
Downton TDF, Wing K, Cosentino SB, Karanth NV. The molecular characteristics of non‐small cell lung cancer in the Northern Territory's Top End. Asia Pac J Clin Oncol 2023. https://doi.org/10.1111/ajco.13967.
Raju S, Ghosh S, Mehta AC. Chest CT signs in pulmonary disease: A pictorial review. Chest 2017; 151: 1356–1374.
Kandel P, Knipe H. Benign vs malignant pulmonary nodule. Reference article [accessed 2023 July 29]. Available from: Radiopaedia.org.
Mazzone PJ, Lam L. Evaluating the patient with a pulmonary nodule: A review. JAMA 2022; 327: 264–273.
Wu Z, Wang F, Cao W, et al. Lung cancer risk prediction models based on pulmonary nodules: A systematic review. Thorac Cancer 2022; 13: 664–677.
MacMahon H, Naidich DP, Goo JM, et al. Guidelines for management of incidental pulmonary nodules detected on CT images: From the Fleischner Society. Radiology 2017; 284: 228–243.
Tammemägi MC, Ruparel M, Tremblay A, et al. USPSTF2013 versus PLCOm2012 lung cancer screening eligibility criteria (International Lung Screening Trial): interim analysis of a prospective cohort study. Lancet Oncol 2022; 23: 138–148.
Bateson EM. Radiological appearances of primary lung cancer in aboriginals of the Northern Territory of Australia. Australas Radiol 1985; 29: 126–129.
Australian Bureau of Statistics. Estimates of Aboriginal and Torres Strait Islander Australians. ABS, Canberra, 2016.
Howarth T, Gahreman D, Ben Saad H, Ng L, Heraganahally SS. Correlation of spirometry indices to chest radiology in the diagnosis of chronic airway disease among regional and rural Indigenous Australians. Intern Med J 2023; 53: 1994–2006.
Anderson K, Diaz A, Parikh DR, Garvey G. Accessibility of cancer treatment services for Indigenous Australians in the Northern Territory: Perspectives of patients and care providers. BMC Health Serv Res 2021; 21: 95.
Heraganahally SS, Howarth T, White E, Sorger L, Biancardi E, Ben Saad H. Lung function parameters among Australian Aboriginal “Apparently Healthy” Adults: an Australian Caucasian and Global Lung Function Initiative (GLI‐2012) various ethnic norms comparative study. Expert Rev Respir Med 2020; 23: 1–11.
Heraganahally SS, Howarth TP, Sorger L. Chest computed tomography findings among adult Indigenous Australians in the Northern Territory of Australia. J Med Imaging Radiat Oncol 2022; 66: 337–344.
National Health and Medical Research Council. Ethical conduct in research with Aboriginal and Torres Strait Islander Peoples and communities: Guidelines for researchers and stakeholders. Commonwealth of Australia, Canberra, 2018 [Accessed June 2023]. Available from: https://www.nhmrc.gov.au.
Tammemagi MC, Schmidt H, Martel S. et al; PanCan Study Team. Participant selection for lung cancer screening by risk modelling (the Pan‐Canadian Early Detection of Lung Cancer [PanCan] study): A single‐arm, prospective study. Lancet Oncol 2017; 18: 1523–1531.
Doss AX, Howarth TP, Ng L, Doss SA, Heraganahally SS. Significance and prognostication of mediastinal lymph node enlargement on chest computed tomography among adult Indigenous Australians. J Med Imaging Radiat Oncol 2023; 67: 726–733.
McWilliams A, Tammemagi MC, Mayo JR, et al. Probability of cancer in pulmonary nodules detected on first screening CT. N Engl J Med 2013; 369: 910–919.
Xu DM, van der Zaag‐Loonen HJ, Oudkerk M, et al. Smooth or attached solid indeterminate nodules detected at baseline CT screening in the NELSON study: Cancer risk during 1 year of follow‐up. Radiology 2009; 250: 264–272.
Lindell RM, Hartman TE, Swensen SJ, et al. Five‐year lung cancer screening experience: CT appearance, growth rate, location, and histologic features of 61 lung cancers. Radiology 2007; 242: 555–562.
Horeweg N, van der Aalst CM, Thunnissen E, et al. Characteristics of lung cancers detected by computer tomography screening in the randomized NELSON trial. Am J Respir Crit Care Med 2013; 187: 848–854.
Peters R, Heuvelmans MA, Vliegenthart R, Van Ooijen PM, De Bock GH, Oudkerk M. Prevalence of pulmonary multi‐nodularity in CT lung cancer screening and lung cancer probability [abstr]. Radiological Society of North America Scientific Assembly and Annual Meeting Program. Radiological Society of North America, Oak Brook, IL, 2015; 111.
Gadgeel SM, Ramalingam S, Cummings G, et al. Lung cancer in patients, 50 years of age: the experience of an academic multidisciplinary program. Chest 1999; 115: 1232–1236.
Wilson DO, Weissfeld JL, Balkan A, et al. Association of radiographic emphysema and airflow obstruction with lung cancer. Am J Respir Crit Care Med 2008; 178: 738–744.
Chiles C, Duan F, Amorosa JK, et al. Sex‐ and gender‐linked differences in baseline characteristics of the National Lung Screening Trial [abstr]. Radiological Society of North America Scientific Assembly and Annual Meeting Program. Radiological Society of North America, Oak Brook, IL, 2015; 111.
Gould MK, Donington J, Lynch WR, et al. Evaluation of individuals with pulmonary nodules: when is it lung cancer? Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence‐based clinical practice guidelines. Chest 2013; 143(5 Suppl): e93S–e120S.
Kruavit A, Fox M, Pearson R, Heraganahally S. Chronic respiratory disease in the regional and remote population of the northern territory top end: a perspective from the specialist respiratory outreach service. Aust J Rural Health 2017; 25: 275–284.
Gibbs C, Howarth T, Ticoalu A, et al. Bronchiectasis among Indigenous adults in the Top End of the Northern Territory, 2011–2020: a retrospective cohort study. Med J Aust 2024; 220: 188–195.
Mehra S, Chang AB, Lam CK, et al. Bronchiectasis among Australian Aboriginal and Non‐Aboriginal patients in the regional and remote population of the Northern Territory of Australia. Rural Remote Health 2021; 21: 6390.
Heraganahally SS, Wasgewatta SL, McNamara K, et al. Chronic obstructive pulmonary disease in Aboriginal patients of the Northern Territory of Australia: A landscape perspective. Int J Chron Obstruct Pulmon Dis 2019; 14: 2205–2217.
Heraganahally SS, Wasgewatta SL, McNamara K, et al. Chronic obstructive pulmonary disease with and without bronchiectasis in Aboriginal Australians – A comparative study. Intern Med J 2020; 50: 1505–1513.
Sze DFL, Howarth TP, Lake CD, Ben Saad H, Heraganahally SS. Differences in the spirometry parameters between indigenous and non‐indigenous patients with COPD: A matched control study. Int J Chron Obstruct Pulmon Dis 2022; 17: 869–881.
Heraganahally SS, Howarth TP, Lloyd A, White E, Veale A, Ben Saad H. The prevalence of bronchodilator responsiveness “asthma” among adult indigenous Australians referred for lung function testing in the top end Northern Territory of Australia. J Asthma Allergy 2022; 15: 1305–1319.
Heraganahally SS, Ghimire RH, Howarth T, Kankanamalage OM, Palmer D, Falhammar H. Comparison and outcomes of emergency department presentations with respiratory disorders among Australian Indigenous and non‐Indigenous patients. BMC Emerg Med 2022; 22: 11.
Heraganahally SS, Silva SAMS, Howarth TP, Kangaharan N, Majoni SW. Comparison of clinical manifestation among Australian Indigenous and non‐Indigenous patients presenting with pleural effusion. Intern Med J 2022; 52: 1232–1241.
Seyedshahabedin MM, Howarth TP, Mo L, Biancardi E, Heraganahally SS. Flexible bronchoscopy indications and outcomes between Indigenous and non‐Indigenous patients in the Northern Territory of Australia. Intern Med J 2022; 53: 1634–1641.
Heraganahally SS, Mortimer N, Howarth T, et al. Utility and outcomes among Indigenous and non‐Indigenous patients requiring domiciliary oxygen therapy in the regional and rural Australian population. Aust J Rural Health 2021; 29: 918–926.
Howarth TP, Saad HB, Perez AJ, Atos CB, White E, Heraganahally SS. Comparison of diffusing capacity of carbon monoxide (DLCO) and total lung capacity (TLC) between Indigenous Australians and Australian Caucasian adults. PLoS One 2021; 16: e0248900.
Heraganahally S, Howarth TP, White E, Ben Saad H. Implications of using the GLI‐2012, GOLD and Australian COPD‐X recommendations in assessing the severity of airflow limitation on spirometry among an Indigenous population with COPD: an Indigenous Australians perspective study. BMJ Open Respir Res 2021; 8: e001135.
Heraganahally SS, Howarth T, Sorger L, Ben Saad H. Sex differences in pulmonary function parameters among Indigenous Australians with and without chronic airway disease. PLoS One 2022; 17: e0263744.
Heraganahally SS, Howarth T, Mo L, Sorger L, Ben Saad H. Critical analysis of spirometric patterns in correlation to chest computed tomography among adult Indigenous Australians with chronic airway diseases. Expert Rev Respir Med 2021; 15: 1229–1238.
Schubert J, Kruavit A, Mehra S, Wasgewatta S, Chang AB, Heraganahally S. Prevalence and nature of lung function abnormalities among Indigenous Australians referred to specialist respiratory outreach clinics in the Northern Territory. Intern Med J 2019; 49: 217–224.
Pal A, Howarth TP, Rissel C, et al. COPD disease knowledge, self‐awareness and reasons for hospital presentations among a predominately Indigenous Australian cohort – A study to explore preventable hospitalization. BMJ Open Respir Res 2022; 9: e001295.
Heraganahally S, Howarth TP, Issac S, et al. Exploring the appropriateness of prescribing practice of inhaled pharmacotherapy among Aboriginal Australians in the Top End Northern Territory of Australia: a retrospective cohort study. BMJ Open Respir Res 2023; 10: e001508.
Heraganahally SS, Ponneri TR, Howarth TP, Saad HB. The effects of inhaled airway directed pharmacotherapy on decline in lung function parameters among Indigenous Australian adults with and without underlying airway disease. Int J Chron Obstruct Pulmon Dis 2021; 16: 2707–2720.
Heraganahally SS, Monsi E, Gadil E, Maze D, Lynch S. Catastrophic effects of using cannabis via bucket bong in Top End Northern Territory of Australia. Am J Trop Med Hyg 2023; 109: 1–6.
Mishra K, Fazal R, Howarth T, Mutai J, Doss AX, Heraganahally SS. Cystic lung disease in adult Indigenous Australians in the Northern Territory of Australia. J Med Imaging Radiat Oncol 2023; 16: 67–73.
González Maldonado S, Delorme S, Hüsing A, et al. Evaluation of prediction models for identifying malignancy in pulmonary nodules detected via low‐dose computed tomography. JAMA Netw Open 2020; 3: e1921221.
فهرسة مساهمة: Keywords: First Nations; Indigenous; lung cancer; malignancy; pulmonary; radiology; respiratory
تواريخ الأحداث: Date Created: 20240322 Latest Revision: 20240322
رمز التحديث: 20240322
DOI: 10.1002/jmrs.783
PMID: 38516966
قاعدة البيانات: MEDLINE
الوصف
تدمد:2051-3909
DOI:10.1002/jmrs.783