دورية أكاديمية
أعرض في EDS

Extragenital Sexually Transmitted Infections Among High-Risk Men Who Have Sex With Men in Johannesburg, South Africa.

التفاصيل البيبلوغرافية
العنوان: Extragenital Sexually Transmitted Infections Among High-Risk Men Who Have Sex With Men in Johannesburg, South Africa.
المؤلفون: Dias BDC; From the Centre for HIV & STIs., Sekgele W; South African Field Epidemiology Training Programme (SAFETP), National Institute for Communicable Diseases., Nhlapo D; From the Centre for HIV & STIs., Mahlangu MP; From the Centre for HIV & STIs., Venter JME; From the Centre for HIV & STIs., Maseko DV; From the Centre for HIV & STIs., Müller EE; From the Centre for HIV & STIs., Greeves M; Engage Men's Health., Botha P; Engage Men's Health., Radebe F; From the Centre for HIV & STIs., Kufa T, Kularatne RS
المصدر: Sexually transmitted diseases [Sex Transm Dis] 2024 Apr 01; Vol. 51 (4), pp. 245-250. Date of Electronic Publication: 2024 Jan 10.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: J B Lippincott Country of Publication: United States NLM ID: 7705941 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-4521 (Electronic) Linking ISSN: 01485717 NLM ISO Abbreviation: Sex Transm Dis Subsets: MEDLINE
أسماء مطبوعة: Publication: Philadelphia Pa : J B Lippincott
Original Publication: Philadelphia, Lippincott.
مواضيع طبية MeSH: Syphilis*/epidemiology , Gonorrhea*/epidemiology , Chlamydia Infections*/epidemiology , Sexual and Gender Minorities* , Sexually Transmitted Diseases*/epidemiology , HIV Infections*/epidemiology, Male ; Humans ; Adult ; Homosexuality, Male ; South Africa ; Cross-Sectional Studies ; Seroepidemiologic Studies ; Neisseria gonorrhoeae ; Chlamydia trachomatis ; Prevalence
مستخلص: Background: In South Africa, extragenital etiological sexually transmitted infection (STI) screening among men who have sex with men (MSM) is not routinely available. We aimed to determine the prevalence of STI pathogens at rectal and pharyngeal sites, syphilis seroprevalence, and associated risk factors among a selection of high-risk MSM without symptomatic urethritis attending a men's health clinic in Johannesburg, South Africa.
Methods: A cross-sectional study was conducted in 2022. Enrolled clients self-reported demographic, sexual behavioral risks, and clinical information. Client or clinician-collected rectal and pharyngeal swabs were tested for Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma genitalium, and Trichomonas vaginalis. C. trachomatis-positive rectal samples were reflex tested for lymphogranuloma venereum. Blood specimens were screened for syphilis. Univariate and multivariate regression models were used to determine factors independently associated with the presence of an extragenital STI or syphilis.
Results: Among the 97 participants (median age, 29 years), 24.7% had an extragenital STI and 9.4% had high nontreponemal antibody titers (rapid plasma reagin ≥1:16). Rectal STIs were detected in 26.4% participants: N. gonorrhoeae (14.3%), C. trachomatis (9.9%), and M. genitalium (5.5%). Pharyngeal STIs were less prevalent (4.1%). Overall, the prevalence of any STI was 41%. Sex under the influence of drugs (adjusted odds ratio, 4.94; 95% confidence interval, 1.56-15.69) and engaging in condomless receptive anal intercourse with a casual partner (adjusted odds ratio, 8.36; 95% confidence interval, 1.73-40.28) were independent risk factors for having an extragenital STI.
Conclusions: The high burden of extragenital STIs and active syphilis in asymptomatic MSM underscores the importance of routine etiological screening in this key population, as the syndromic approach would not enable detection or treatment of these infections.
Competing Interests: Conflict of Interest and Sources of Funding: The authors have no conflicts of interest to declare. This work was internally funded by the Centre of HIV & STIs at the National Institute for Communicable Diseases, a division of the National Health Laboratory Service, South Africa.
(Copyright © 2024 American Sexually Transmitted Diseases Association. All rights reserved.)
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تواريخ الأحداث: Date Created: 20240327 Date Completed: 20240328 Latest Revision: 20240328
رمز التحديث: 20240329
DOI: 10.1097/OLQ.0000000000001927
PMID: 38534082
قاعدة البيانات: MEDLINE
الوصف
تدمد:1537-4521
DOI:10.1097/OLQ.0000000000001927