دورية أكاديمية
Perfluorobutane (Sonazoid) Contrast-enhanced ultrasound to diagnose hepatocellular carcinoma: A systematic review and meta-analysis.
| العنوان: | Perfluorobutane (Sonazoid) Contrast-enhanced ultrasound to diagnose hepatocellular carcinoma: A systematic review and meta-analysis. |
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| المؤلفون: | Chen Y; Department of Ultrasound, Affiliated Hospital of Jiaxing University, First Hospital of Jiaxing, Jiaxing. cyjzjhn@163.com., Zhu W; Department of Ultrasound, Affiliated Hospital of Jiaxing University, First Hospital of Jiaxing, Jiaxing., Yi Y; Department of Ultrasound, Affiliated Hospital of Jiaxing University, First Hospital of Jiaxing, Jiaxing., Cao H; Department of Ultrasound, Affiliated Hospital of Jiaxing University, First Hospital of Jiaxing, Jiaxing., Chen F; Department of Ultrasound, Affiliated Hospital of Jiaxing University, First Hospital of Jiaxing, Jiaxing., Zhu Q; Department of Ultrasound, Affiliated Hospital of Jiaxing University, First Hospital of Jiaxing, Jiaxing. |
| المصدر: | Medical ultrasonography [Med Ultrason] 2024 Jun 21; Vol. 26 (2), pp. 187-196. Date of Electronic Publication: 2024 Feb 25. |
| نوع المنشور: | Meta-Analysis; Systematic Review; Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: |
| أسماء مطبوعة: | Original Publication: Cluj, Romania : "Iuliu Haţieganu" Medical Pub. House |
| مواضيع طبية MeSH: | Carcinoma, Hepatocellular*/diagnostic imaging , Contrast Media* , Iron* , Liver Neoplasms*/diagnostic imaging , Oxides* , Ultrasonography*/methods, Humans ; Diagnosis, Differential ; Ferric Compounds ; Image Enhancement/methods ; Liver/diagnostic imaging ; Reproducibility of Results ; Sensitivity and Specificity |
| مستخلص: | Aim: This meta-analysis aimed to assess the precision of Sonazoid contrast-enhanced ultrasound (CEUS) to distinguish hepatocellular carcinoma (HCC) from focal liver lesions (FLLs). Material and Methods: The Cochrane Library, Embase, PubMed, and Web of Science databases were systematically searched and checked for studies using Sonazoid CEUS to characterize HCC. A comprehensive meta-analysis was conducted, involving data pooling, subgroup analyses, meta-regression, and investigation of publication bias. Results: The meta-analysis included fourteen studies. The overall diagnostic accuracy for characterizing HCC was as follows (all ranges show the 95% confidence interval): pooled sensitivity of 0.87 (0.80-0.92), pooled specificity of 0.95 (0.91-0.97), and a diagnostic odds ratio of 121 (61-241). The overall weighted area under the curve was 0.97 (0.95-0.98). The pooled sensitivity, specificity, and diagnostic odds ratio for Sonazoid and Sonovue were 0.75 (0.63- 0.84), 0.97 (0.86-0.99), 82 (15-445); and 0.64 (0.51-0.76), 0.98 (0.91-0.99), 72 (17-311), respectively. The sources of heterogeneity were identified as the study location, prevailing risk factor, reference diagnosis standard, criteria of Sonazoid CUES, and the proportion of cases of HCC. We observed no potential publication bias. Conclusion: Sonazoid CEUS is efficient to distinguish HCC from FLLs, with good sensitivity and specificity. It is comparable to Sonovue CEUS to diagnose HCC. |
| المشرفين على المادة: | 0 (Contrast Media) 0 (Ferric Compounds) E1UOL152H7 (Iron) 0 (Oxides) 0 (Sonazoid) |
| تواريخ الأحداث: | Date Created: 20240327 Date Completed: 20240623 Latest Revision: 20240717 |
| رمز التحديث: | 20240717 |
| DOI: | 10.11152/mu-4334 |
| PMID: | 38537180 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2066-8643 |
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| DOI: | 10.11152/mu-4334 |