دورية أكاديمية
Candida auris outbreak at a tertiary care hospital during the COVID-19 pandemic.
| العنوان: | Candida auris outbreak at a tertiary care hospital during the COVID-19 pandemic. |
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| المؤلفون: | Dbeibo L; Division of Infectious Diseases, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN; Division of Infection Prevention, Indiana University Health, Indianapolis, IN. Electronic address: ldbeibo@iu.edu., Beeler C; Division of Infectious Diseases, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN; Division of Infection Prevention, Indiana University Health, Indianapolis, IN., Clark L; Division of Infection Prevention, Indiana University Health, Indianapolis, IN., Zondor M; Division of Infection Prevention, Indiana University Health, Indianapolis, IN., Sartino C; Division of Infection Prevention, Indiana University Health, Indianapolis, IN., Relich RF; Division of Clinical Microbiology, Indiana University Health, Indianapolis, IN; Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN., Hazen D; Division of Infection Prevention, Indiana University Health, Indianapolis, IN., Lyons K; Division of Infection Prevention, Indiana University Health, Indianapolis, IN., Kelley K; Division of Infection Prevention, Indiana University Health, Indianapolis, IN., Webb D; Division of Infection Prevention, Indiana University Health, Indianapolis, IN., Saysana M; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN., Kara A; Division of General Internal Medicine and Geriatrics, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN. |
| المصدر: | American journal of infection control [Am J Infect Control] 2024 Aug; Vol. 52 (8), pp. 878-883. Date of Electronic Publication: 2024 Mar 25. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Mosby Country of Publication: United States NLM ID: 8004854 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-3296 (Electronic) Linking ISSN: 01966553 NLM ISO Abbreviation: Am J Infect Control Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: St. Louis, Mosby |
| مواضيع طبية MeSH: | Tertiary Care Centers*/statistics & numerical data , COVID-19*/epidemiology , COVID-19*/prevention & control , Disease Outbreaks* , Candidiasis*/epidemiology , Candidiasis*/microbiology , Candidiasis*/prevention & control , SARS-CoV-2* , Candida auris*, Humans ; Male ; Female ; Middle Aged ; Aged ; Adult ; Cross Infection/epidemiology ; Cross Infection/prevention & control ; Cross Infection/microbiology ; Infection Control/methods ; Contact Tracing ; Aged, 80 and over ; Candidiasis, Invasive |
| مستخلص: | Background: Candida auris (C auris) is a fungal pathogen that has the potential for environmental persistence leading to outbreaks in health care settings. There has been a worldwide surge in C auris outbreaks during the COVID-19 pandemic. In this report, we describe an outbreak of C auris, its control, patient outcomes, and lessons learned. Methods: The outbreak occurred in a 600-bed adult academic tertiary care hospital. Contact tracing was initiated immediately after identification of the index case and surveillance testing for C auris was obtained from patients who were exposed to the index case. Infection prevention measures were closely followed. Results: A total of 560 cultures were performed on 453 unique patients between August 2021 and December 2021. Of those, 31 cultures (5.5%) were positive for C auris; 27 (87.1%) were colonized with C auris, while 4 patients developed a clinical infection (12.9%). The secondary attack rate was 6.8% (31/453). The 30-day all-cause mortality rate for all patients who tested positive for C auris was 9.7%. Discussion: C auris can cause protracted outbreaks that result in colonization and invasive infections. Multidisciplinary work to improve adherence to infection prevention measures as well as targeted admission screening are essential to limit outbreaks. (Copyright © 2024 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Admission screening; Fungal infections; Transmission |
| SCR Disease Name: | Candida auris infection |
| تواريخ الأحداث: | Date Created: 20240327 Date Completed: 20240721 Latest Revision: 20240808 |
| رمز التحديث: | 20240808 |
| DOI: | 10.1016/j.ajic.2024.03.012 |
| PMID: | 38537678 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1527-3296 |
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| DOI: | 10.1016/j.ajic.2024.03.012 |