دورية أكاديمية
Tetralogy of Fallot complicated by multiple cerebral abscesses in a child: a case report.
| العنوان: | Tetralogy of Fallot complicated by multiple cerebral abscesses in a child: a case report. |
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| المؤلفون: | Kamabu LK; Department of Surgery, Neurosurgery, College of Health Medicine, Makerere University, Mulago Upper Hill, Kampala, Uganda. kamabularry@gmail.com.; Faculty of Medicine, Université Catholique du Graben, Butembo, Democratic Republic of the Congo. kamabularry@gmail.com., Sikakulya FK; Faculty of Medicine, Université Catholique du Graben, Butembo, Democratic Republic of the Congo.; Department of Surgery, Kampala International University, Western Campus, Kampala, Uganda., Kataka LM; Faculty of Medicine, Université Catholique du Graben, Butembo, Democratic Republic of the Congo., Vivalya BNM; Department of Internal Medicine, Masereka General Hospital, North-Kivu, Democratic Republic of the Congo.; Department of Psychiatry and Mental Health, Kampala International University Western Campus, Ishaka, Uganda., Lekuya HM; Department of Surgery, Neurosurgery, College of Health Medicine, Makerere University, Mulago Upper Hill, Kampala, Uganda.; Directorate of Surgical Services, Neurosurgical Unit, Mulago National Referral Hospital, Kampala, Uganda., Obiga DOD; Department of Surgery, Neurosurgery, College of Health Medicine, Makerere University, Mulago Upper Hill, Kampala, Uganda.; Directorate of Surgical Services, Neurosurgical Unit, Mulago National Referral Hospital, Kampala, Uganda., Sekabunga JN; Department of Surgery, Neurosurgery, College of Health Medicine, Makerere University, Mulago Upper Hill, Kampala, Uganda.; Directorate of Surgical Services, Neurosurgical Unit, Mulago National Referral Hospital, Kampala, Uganda., Bbosa GS; Department of Pharmacology & Therapeutics, Makerere University College of Health Sciences, Kampala, Uganda. |
| المصدر: | Journal of medical case reports [J Med Case Rep] 2024 Mar 28; Vol. 18 (1), pp. 183. Date of Electronic Publication: 2024 Mar 28. |
| نوع المنشور: | Case Reports; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: BioMed Central Country of Publication: England NLM ID: 101293382 Publication Model: Electronic Cited Medium: Internet ISSN: 1752-1947 (Electronic) Linking ISSN: 17521947 NLM ISO Abbreviation: J Med Case Rep Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: [London] : BioMed Central, [2007- |
| مواضيع طبية MeSH: | Brain Abscess*/complications , Brain Abscess*/diagnostic imaging , Heart Defects, Congenital*/complications , Tetralogy of Fallot*/complications , Tetralogy of Fallot*/diagnostic imaging , Tetralogy of Fallot*/surgery, Child, Preschool ; Humans ; Male ; Anti-Bacterial Agents/therapeutic use ; Ceftriaxone/therapeutic use ; Cyanosis/drug therapy |
| مستخلص: | Introduction: Brain abscesses are rare but potentially fatal condition and can be associated with cyanotic congenital heart disease of which 5-18.7% of these patients that develop cerebral abscess commonly have tetralogy of Fallot (TOF). Case Presentation: We report a case of 3-year-old Muganda male that presented with convulsions, cyanosis and difficulty in breathing. The patient had a combination intervention of medical treatment and surgical drainage of the abscess. Post-operative Computerized tomography scan images and pre-operative brain Computerized tomography scans were compared. The multiple rings enhancing lesions were reduced in number and sizes. The largest measured ring was 44 × 22.5×16mm compared to the previous; 42 × 41×36mm. The mass effect had reduced from 16 mm to 7.5 mm. The periventricular hypodensities persisted. Findings showed radiological improvement with residual abscesses, subacute subdural hematoma and pneumocranium. The patient was treated with intravenous ceftriaxone 1 g OD for six weeks and he showed marked improvement and was discharged home after 3 months. Conclusion: A comprehensive strategy involving medications, surgical drainage, and early neurosurgical consultation is vital in treating brain abscesses in uncorrected TOF. Early identification of the pathogen, appropriate antibiotic therapy, and vigilant follow-up through clinical assessments and imaging are crucial, potentially spanning a 4-8-week treatment. (© 2024. The Author(s).) |
| References: | Heart. 2015 Mar;101(6):485-94. (PMID: 25301858) World Neurosurg. 2017 Nov;107:124-129. (PMID: 28780403) J Neurosci Rural Pract. 2013 Aug;4(Suppl 1):S67-81. (PMID: 24174804) Acta Paediatr. 2010 Aug;99(8):1163-7. (PMID: 20222876) Cardiol Clin. 1993 Nov;11(4):689-99. (PMID: 8252568) J Am Coll Cardiol. 2006 Jul 18;48(2):356-65. (PMID: 16843187) |
| فهرسة مساهمة: | Keywords: And medical management; Child; Multiple cerebral abscesses; Surgical drainage; Tetralogy of Fallot |
| المشرفين على المادة: | 0 (Anti-Bacterial Agents) 75J73V1629 (Ceftriaxone) |
| تواريخ الأحداث: | Date Created: 20240328 Date Completed: 20240329 Latest Revision: 20240408 |
| رمز التحديث: | 20240408 |
| مُعرف محوري في PubMed: | PMC10976810 |
| DOI: | 10.1186/s13256-024-04451-0 |
| PMID: | 38539274 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1752-1947 |
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| DOI: | 10.1186/s13256-024-04451-0 |