دورية أكاديمية
أعرض في EDS

Age Is a Predictor of In-Hospital Outcomes for Left Ventricular Assist Device Implantation: A Nationwide Analysis.

التفاصيل البيبلوغرافية
العنوان: Age Is a Predictor of In-Hospital Outcomes for Left Ventricular Assist Device Implantation: A Nationwide Analysis.
المؤلفون: Akkawi AR; Department of Internal Medicine, Kansas University School of Medicine-Wichita, Wichita, KS 67214, USA., Yamaguchi A; Division of Cardiovascular Surgery, University of Tsukuba, Tsukuba 305-8577, Ibaraki, Japan., Shimamura J; Division of Cardiothoracic Surgery, Department of Surgery, Westchester Medical Center, Valhalla, NY 10595, USA., Chehab O; Division of Cardiology, Department of Medicine, Johns Hopkins University Baltimore, Baltimore, MD 21218, USA., Alvarez P; Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH 44195, USA., Kuno T; Division of Cardiology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA., Briasoulis A; Division of Cardiovascular Medicine, Section of Heart Failure and Transplantation, University of Iowa, Iowa City, IA 52242, USA.
المصدر: Journal of personalized medicine [J Pers Med] 2024 Feb 22; Vol. 14 (3). Date of Electronic Publication: 2024 Feb 22.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101602269 Publication Model: Electronic Cited Medium: Print ISSN: 2075-4426 (Print) Linking ISSN: 20754426 NLM ISO Abbreviation: J Pers Med Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI AG, 2011-
مستخلص: The 2018 heart allocation system has significantly influenced heart transplantation and left ventricular assist device (LVAD) utilization. Our study aims to investigate age-related outcomes following LVAD implantation in the post-allocation era. Using the National Inpatient Sample, we analyzed data from 7375 patients who underwent LVAD implantation between 2019 and 2020. The primary endpoint was in-hospital mortality following LVAD implantation, stratified by age categories. The age groups were 18-49, 50-59, 60-69, and over 70. These represented 26%, 26%, 31%, and 17% of patients, respectively. Patients aged 60-69 and those over 70 exhibited higher in-hospital mortality rates of 12% and 17%, respectively, compared to younger age groups (7% for 18-49 and 6% for 50-59). The age groups 60-69 and over 70 were independent predictors of mortality, with adjusted odds ratios of 1.99 ( p = 0.02; 95% confidence interval [CI], 1.12-3.57) and 2.88 ( p = 0.002; 95% CI, 1.45-5.71), respectively. Additionally, a higher Charlson Comorbidity Index was associated with increased in-hospital mortality risk (adjusted odds ratio 1.39; p = 0.02; 95% CI, 1.05-1.84). Additionally, patients above 70 experienced a statistically shorter length of stay. Nonhome discharge was found to be significantly high across all age categories. However, the difference in hospitalization cost was not statistically significant across the age groups. Our study highlights that patients aged 60 and above face an increased risk of in-hospital mortality following LVAD implantation in the post-allocation era. This study sheds light on age-related outcomes and emphasizes the importance of considering age in LVAD patient selection and management strategies.
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فهرسة مساهمة: Keywords: heart allocation system; in-hospital mortality; left ventricular assist device
تواريخ الأحداث: Date Created: 20240328 Latest Revision: 20240330
رمز التحديث: 20240330
مُعرف محوري في PubMed: PMC10970890
DOI: 10.3390/jpm14030236
PMID: 38540978
قاعدة البيانات: MEDLINE
الوصف
تدمد:2075-4426
DOI:10.3390/jpm14030236