دورية أكاديمية
Social isolation and cognitive function in patients with schizophrenia: A two years follow-up study.
| العنوان: | Social isolation and cognitive function in patients with schizophrenia: A two years follow-up study. |
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| المؤلفون: | Yu B; School of Education, Tianjin University, Tianjin, China; Institute of Applied Psychology, Tianjin University, Tianjin, China; Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, China. Electronic address: yubin@tju.edu.cn., Sun Z; School of Education, Tianjin University, Tianjin, China; Institute of Applied Psychology, Tianjin University, Tianjin, China., Li S; Institute of Mental Health, Tianjin Anding Hospital, Mental Health Center of Tianjin Medical University, Tianjin, China., Chien IC; Division of General Psychiatry, Yuli Hospital, Ministry of Health and Welfare, Taiwan., Ku PW; Graduate Institute of Sports and Health Management, National Chung Hsing University, Taiwan; Department of Behavioural Science and Health, University College London, London, UK. Electronic address: powen.ku@nchu.edu.tw., Chen LJ; Department of Exercise Health Science, National Taiwan University of Sport, Taiwan; Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK. Electronic address: ljchen@gm.ntus.edu.tw. |
| المصدر: | Schizophrenia research [Schizophr Res] 2024 May; Vol. 267, pp. 150-155. Date of Electronic Publication: 2024 Mar 27. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Science Publisher B. V Country of Publication: Netherlands NLM ID: 8804207 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2509 (Electronic) Linking ISSN: 09209964 NLM ISO Abbreviation: Schizophr Res Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Amsterdam : Elsevier Science Publisher B. V., c1988- |
| مواضيع طبية MeSH: | Schizophrenia*/physiopathology , Schizophrenia*/complications , Social Isolation* , Cognitive Dysfunction*/etiology , Cognitive Dysfunction*/physiopathology, Humans ; Male ; Female ; Adult ; Follow-Up Studies ; Middle Aged ; Longitudinal Studies ; Taiwan ; Schizophrenic Psychology |
| مستخلص: | Cognitive impairment is a core characteristic of schizophrenia. Social isolation has been linked to impaired cognitive function among the general population. In this longitudinal study, we examined the association between social isolation and cognitive function among inpatients with schizophrenia. Two waves of data (2019 and 2021) were collected from chronic psychiatric wards. A total of 166 inpatients completed all measurements at baseline and follow-up. Social isolation was measured by incorporating the frequency of social contact and participation, while cognitive functions were assessed by the Taiwan version of the Montreal Cognitive Assessment (MoCA-T). We used multiple linear regression to evaluate the link between baseline social isolation and cognitive function. For the total sample, social isolation was significantly related to poor language abilities (β = -0.17, p = 0.013) and delayed recall (β = -0.15, p = 0.023). Sex-stratified analysis showed that social isolation was significantly related to poor global cognitive function (β = -0.14, p = 0.021) and domain-specific cognitive functions including language abilities (β = -0.26, p = 0.003) and delayed recall (β = -0.19, p = 0.045) in male inpatients. No significant association was found between social isolation and global cognitive function or any cognitive domain (all ps > 0.05) for females. All associations were independent of loneliness and other covariates. These findings suggested that social isolation could predict poor subsequent cognitive function in inpatients with schizophrenia, especially in males. Interventions aimed at enhancing social connections could potentially improve cognitive function in this population. Competing Interests: Declaration of competing interest The authors declare no conflicts of interest. (Copyright © 2024 Elsevier B.V. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Cognitive function; Schizophrenia; Sex differences; Social isolation |
| تواريخ الأحداث: | Date Created: 20240328 Date Completed: 20240519 Latest Revision: 20240519 |
| رمز التحديث: | 20240520 |
| DOI: | 10.1016/j.schres.2024.03.035 |
| PMID: | 38547717 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1573-2509 |
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| DOI: | 10.1016/j.schres.2024.03.035 |