دورية أكاديمية
أعرض في EDS

Transcatheter aortic valve replacement achieves similar predicted effective orifice area to surgical aortic valve replacement in bicuspid aortic stenosis.

التفاصيل البيبلوغرافية
العنوان: Transcatheter aortic valve replacement achieves similar predicted effective orifice area to surgical aortic valve replacement in bicuspid aortic stenosis.
المؤلفون: Connolly JE; Department of Internal Medicine, Johns Hopkins Hospital, Baltimore, MD 21224, USA., Herrmann HC; Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA., Atluri P; Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA., Desai N; Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA., Fiorilli PN; Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA., Giri J; Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA., Li RH; Division of Cardiovascular Medicine, Penn Presbyterian Medical Center, Philadelphia, PA 19104, USA., Kobayashi T; Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA., Nathan AS; Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA., Szeto WY; Division of Cardiovascular Surgery, Penn Presbyterian Medical Center, Philadelphia, PA 19104, USA., Grimm JC; Institute for Cardiovascular Health, University of Texas Health Austin, Austin, TX 78712, USA. Electronic address: joshua.grimm@austin.utexas.edu.
المصدر: Cardiovascular revascularization medicine : including molecular interventions [Cardiovasc Revasc Med] 2024 Sep; Vol. 66, pp. 21-26. Date of Electronic Publication: 2024 Mar 21.
نوع المنشور: Journal Article; Comparative Study
اللغة: English
بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 101238551 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0938 (Electronic) Linking ISSN: 18780938 NLM ISO Abbreviation: Cardiovasc Revasc Med Subsets: MEDLINE
أسماء مطبوعة: Original Publication: New York, NY : Elsevier, c2005-
مواضيع طبية MeSH: Aortic Valve*/surgery , Aortic Valve*/diagnostic imaging , Aortic Valve*/physiopathology , Aortic Valve*/abnormalities , Aortic Valve Stenosis*/surgery , Aortic Valve Stenosis*/diagnostic imaging , Aortic Valve Stenosis*/physiopathology , Transcatheter Aortic Valve Replacement*/instrumentation , Transcatheter Aortic Valve Replacement*/adverse effects , Bicuspid Aortic Valve Disease*/surgery , Bicuspid Aortic Valve Disease*/diagnostic imaging , Bicuspid Aortic Valve Disease*/physiopathology , Heart Valve Prosthesis* , Prosthesis Design* , Heart Valve Prosthesis Implantation*/instrumentation , Heart Valve Prosthesis Implantation*/adverse effects, Humans ; Retrospective Studies ; Female ; Male ; Treatment Outcome ; Aged ; Aged, 80 and over ; Risk Factors ; Heart Valve Diseases/surgery ; Heart Valve Diseases/diagnostic imaging ; Heart Valve Diseases/physiopathology ; Hemodynamics ; Recovery of Function ; Middle Aged ; Time Factors
مستخلص: Background: Studies comparing transcatheter and surgical aortic valve replacement (TAVR and SAVR) for patients with trileaflet aortic stenosis (AS) have found similar or larger effective orifice area (EOA) for TAVR prostheses. To our knowledge, no studies have compared EOA in patients undergoing TAVR versus SAVR for bicuspid AS.
Methods: We retrospectively compared prosthetic valvular sizing and predicted EOA for patients with bicuspid AS undergoing TAVR or SAVR at our institution between January 1, 2016, and December 31, 2021. We excluded patients undergoing procedures for indications other than AS and those without a pre-procedural gated Chest CT. Comparisons included demographics, comorbidities, annular size, prosthetic valve size, predicted EOA and prosthesis-patient mismatch (PPM) for TAVR (N = 78) and SAVR (N = 74) cohorts.
Results: TAVR patients had smaller pre-procedural annular area (501.7 mm 2 vs. 571.8 mm 2 , p < 0.05) and annular perimeter (80.6 mm vs. 86.5 mm, p < 0.05), but larger mean implanted prosthetic valve size (26.4 mm vs 24.2 mm, p < 0.001) compared to SAVR patients. No differences were observed in predicted EOA, predicted EOA indexed to patient body surface area (EOAi), or predicted PPM grade between TAVR and SAVR groups, including in cohorts sorted by pre-procedural annular size.
Conclusions: For bicuspid AS patients undergoing aortic valve replacement, TAVR achieves similar predicted EOA to SAVR. These data support the use of TAVR in selected patients with bicuspid AS and can inform heart team discussions.
Competing Interests: Declaration of competing interest JEC declares no relevant financial relationships or conflicts of interest. HCH reports institutional research funding from Abbott, Boston Scientific, Edwards Lifesciences, and Medtronic, as well as consultant fees from Edwards Lifesciences and Medtronic. PA reports speaking fees from Edwards Lifesciences. PNF receives consulting honoraria from Edwards Lifesciences. JG reports serving on advisory boards and receiving research funds to the institution from Abiomed, Edwards Lifesciences, Inari Medical, and Recor Medical, as well as equity in Endovascular Engineering. RHL has no relevant financial conflicts of interest. TK has no relevant financial conflicts of interest. ASN reports speaker fees and institutional research funds from Edwards Lifesciences. WYS has served on the advisory board and as an investigator and speaker for Edwards Lifesciences, Medtronic, and Abbott.
(Published by Elsevier Inc.)
فهرسة مساهمة: Keywords: Bicuspid aortic stenosis; SAVR; TAVR
تواريخ الأحداث: Date Created: 20240329 Date Completed: 20240830 Latest Revision: 20240830
رمز التحديث: 20240831
DOI: 10.1016/j.carrev.2024.03.017
PMID: 38553277
قاعدة البيانات: MEDLINE
الوصف
تدمد:1878-0938
DOI:10.1016/j.carrev.2024.03.017