دورية أكاديمية
أعرض في EDS

Ejaculatory and erectile function outcomes following holmium laser enucleation of the prostate.

التفاصيل البيبلوغرافية
العنوان: Ejaculatory and erectile function outcomes following holmium laser enucleation of the prostate.
المؤلفون: Roper C; Indiana University School of Medicine, Indianapolis, Indiana, USA., Slade A; Department of Urology, Indiana University Health, Indianapolis, Indiana, USA., Caras R; Department of Urology, Indiana University Health, Indianapolis, Indiana, USA., Shelton T; Department of Urology, Indiana University Health, Indianapolis, Indiana, USA., Rivera M; Department of Urology, Indiana University Health, Indianapolis, Indiana, USA.
المصدر: The Prostate [Prostate] 2024 Jun; Vol. 84 (9), pp. 791-796. Date of Electronic Publication: 2024 Apr 01.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8101368 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0045 (Electronic) Linking ISSN: 02704137 NLM ISO Abbreviation: Prostate Subsets: MEDLINE
أسماء مطبوعة: Publication: <2005-> : Hoboken, NJ : Wiley-Liss
Original Publication: New York : Alan R. Liss, c1980-
مواضيع طبية MeSH: Lasers, Solid-State*/therapeutic use , Lasers, Solid-State*/adverse effects , Prostatic Hyperplasia*/surgery , Ejaculation*/physiology , Erectile Dysfunction*/etiology , Erectile Dysfunction*/physiopathology , Prostatectomy*/adverse effects , Prostatectomy*/methods, Humans ; Male ; Aged ; Retrospective Studies ; Middle Aged ; Postoperative Complications/etiology ; Postoperative Complications/epidemiology ; Surveys and Questionnaires ; Treatment Outcome ; Penile Erection/physiology ; Laser Therapy/methods ; Laser Therapy/adverse effects
مستخلص: Purpose: Holmium laser enucleation of the prostate (HoLEP) is a surgical treatment option for benign prostatic hyperplasia (BPH). Many men develop retrograde ejaculation postprocedure, but there is conflicting evidence regarding sexual function outcomes post-HoLEP. We sought to examine significant variations in patient-reported erectile and ejaculatory function within 12 months post-HoLEP.
Materials and Methods: We conducted a retrospective study for patients who underwent HoLEP between Nov 2018 and Feb 2022. Of the reviewed patients, 277 patients met inclusion criteria and completed pre and postoperative questionnaires, which included the Male Sexual Health Questionnaire- Ejaculatory Dysfunction (MSHQ-EJD) and the International Index of Erectile Function/Sexual Health Inventory for Men (IIEF-5/SHIM). Surveys were provided to patients up to 12 months postprocedure. Demographics and comorbidities associated with sexual dysfunction were collected. Responses to each question were analyzed to detect sub-categorical variations in sexual function as the secondary objective. Data was analyzed by using a linear mixed model.
Results: There was a significant decline in total scores for the MSHQ-EJD (8.70 pre-HoLEP vs. 6.58 post HoLEP, p ≤ 0.001) including a significant decline (p < 0.005) in questions 1-3 which assess ejaculatory ability, strength, and volume. There was not a significant decline in question 4 which assesses bother (2.552 pre-HoLEP vs. 3.119 post-HoLEP, p = 0.526). There was not a significant decline in the IIEF-5/SHIM postoperatively (11.51 pre-HoLEP vs. 13.327 post-HoLEP, p = 0.498).
Conclusions: Patients undergoing HoLEP do not experience a decline in erectile function. Patients do experience a decline in ejaculatory function but did not find this bothersome.
(© 2024 The Authors. The Prostate published by Wiley Periodicals LLC.)
References: Chute CG, Panser LA, Girman CJ, et al. The prevalence of prostatism: a population‐based survey of urinary symptoms. J Urol. 1993;150(1):85‐89. doi:10.1016/s0022-5347(17)35405-8.
Patel N, Parsons J. Epidemiology and etiology of benign prostatic hyperplasia and bladder outlet obstruction. Indian J Urol. 2014;30(2):170‐176.
Shigemura K, Fujisawa M. Current status of holmium laser enucleation of the prostate. Int J Urol. 2018;25(3):206‐211. doi:10.1111/iju.13507.
McVary KT, Roehrborn CG, Avins AL, et al. Update on AUA guideline on the management of benign prostatic hyperplasia. J Urol. 2011;185(5):1793‐1803.
Gilling PJ, Wilson LC, King CJ, Westenberg AM, Frampton CM, Fraundorfer MR. Long‐ term results of a randomized trial comparing holmium laser enucleation of the prostate and transurethral resection of the prostate: results at 7 years. BJU Int. 2012;109(3):408‐411.
Wisenbaugh ES, Nunez‐Nateras R, Mmeje CO, Warner JN, Humphreys MR. Does prostate morphology affect outcomes after holmium laser enucleation. Urology. 2013;81(4):844‐848. doi:10.1016/j.urology.2013.01.006.
Placer J, Salvador C, Planas J, et al. Effects of holmium laser enucleation of the prostate on sexual function. J Endourol. 2015;29(3):332‐339.
Kim S, Yang HK, Lee HE, Paick JS, Oh SJ. HoLEP does not affect the overall sexual function of BPH patients: a prospective study. Asian J Androl. 2014;16(6):873‐877.
Elshal AM, El‐Assmy A, Mekkawy R, et al. Prospective controlled assessment of men's sexual function changes following holmium laser enucleation of the prostate for treatment of benign prostate hyperplasia. Int Urol Nephrol. 2017;49(10):1741‐1749. doi:10.1007/s11255-017-1649-0.
Klett DE, Tyson 2nd, MD, Mmeje CO, Nunez–Nateras R, Chang YH, Humphreys MR. Patient‐reported sexual outcomes after holmium laser enucleation of the prostate: a 3‐year follow‐up study. Urology. 2014;84(2):421‐426. doi:10.1016/j.urology.2014.04.042.
Capogrosso P, Ventimiglia E, Ferrari M, et al. Long‐term sexual outcomes after holmium laser enucleation of the prostate: which patients could benefit the most? Int J Impotence Res. 2016;28(5):189‐193. doi:10.1038/ijir.2016.29.
Rosen R, Cappelleri J, Smith M, Lipsky J, Peña B. Development and evaluation of an abridged, 5‐item version of the International Index of Erectile Function (IIEF‐5) as a diagnostic tool for erectile dysfunction. Int J Impotence Res. 1999;11:319‐326.
Rosen RC, Catania J, Pollack L, Althof S, O'Leary M, Seftel AD. Male sexual health questionnaire (MSHQ): scale development and psychometric validation. Urology. 2004;64:777‐782.
Deslandes M, Klein C, Marquette T, et al. Influence of holmium laser enucleation of the prostate on erectile function: results of a multicentric analysis of 235 patients. World J Urol. 2022;40(11):2747‐2754. doi:10.1007/s00345-022-04175-0.
Kuebker JM, Miller NL. Holmium laser enucleation of the prostate: patient selection and outcomes. Curr Urol Rep. 2017;18(12):96. doi:10.1007/s11934-017-0746-z.
Kim JK, Cho MC, Son H, Ku JH, Oh SJ, Paick JS. Patient perception of ejaculatory volume reduction after holmium laser enucleation of the prostate (HoLEP). Urology. 2017;99:142‐147. doi:10.1016/j.urology.2016.09.037.
Kasman AM, Bhambhvani HP, Eisenberg ML. Ejaculatory dysfunction in patients presenting to a men's health clinic: a retrospective cohort study. Sex Med. 2020;8(3):454‐460. doi:10.1016/j.esxm.2020.05.002.
Enikeev D, Glybochko P, Rapoport L, et al. Impact of endoscopic enucleation of the prostate with thulium fiber laser on the erectile function. BMC Urol. 2018;18(1):87. doi:10.1186/s12894-018-0400-1.
Gu M, Chen Y, Liu C, et al. Comparison of holmium laser enucleation and plasmakinetic resection of prostate: a randomized trial with 72‐month follow‐up. J Endourol. 2018;32(2):139‐143.
فهرسة مساهمة: Keywords: HoLEP; ejaculatory function; erectile function
تواريخ الأحداث: Date Created: 20240401 Date Completed: 20240509 Latest Revision: 20240509
رمز التحديث: 20240509
DOI: 10.1002/pros.24697
PMID: 38558096
قاعدة البيانات: MEDLINE
الوصف
تدمد:1097-0045
DOI:10.1002/pros.24697