دورية أكاديمية
Pediatric poisoning management: How clinical practice can benefit from forensic approach.
العنوان: | Pediatric poisoning management: How clinical practice can benefit from forensic approach. |
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المؤلفون: | Basilicata P; Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy., Marisei M; Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy., Guadagni R; Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy., Sibilio M; U.O.C. Pediatria 1 - A.O.R.N. 'Santobono-Pausilipon', Naples, Italy., Niola M; Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy., Pieri M; Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy. |
المصدر: | Journal of forensic sciences [J Forensic Sci] 2024 Jul; Vol. 69 (4), pp. 1501-1507. Date of Electronic Publication: 2024 Apr 01. |
نوع المنشور: | Case Reports; Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Blackwell Pub Country of Publication: United States NLM ID: 0375370 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1556-4029 (Electronic) Linking ISSN: 00221198 NLM ISO Abbreviation: J Forensic Sci Subsets: MEDLINE |
أسماء مطبوعة: | Publication: 2006- : Malden, MA : Blackwell Pub. Original Publication: [Chicago, Ill.] : Callaghan and Co., 1956- |
مواضيع طبية MeSH: | Forensic Toxicology* , Poisoning*/diagnosis , Poisoning*/therapy , Buprenorphine*/poisoning, Humans ; Narcotics/poisoning ; Narcotics/analysis ; Algorithms ; Specimen Handling ; Child, Preschool ; Male ; Child ; Analgesics, Opioid/poisoning ; Medical History Taking ; Female |
مستخلص: | Pediatric population represents the most vulnerable and at risk for unintentional poisoning, with children younger than 6 years old accounting for nearly half of poison exposures. Poisoning is a time-dependent emergency. The need to reach a scientific agreement on diagnostic protocol and treatment seems to be crucial to reduce morbidity and mortality. Starting from a buprenorphine pediatric intoxication case, this article highlights the limits and pitfalls of the traditional diagnostic approach. Diagnosis of drug intoxication was achieved after several days when an in-depth diagnostic investigation became necessary and complete forensic toxicological analyses were performed. Results evidenced an alarming lack of an unequivocal diagnostic protocol in case of suspect intoxication in structures not provided with a forensic toxicological service/unit. Collection of biological specimens according to forensic protocols at hospitalization plays a paramount role in the definitive diagnosis of intoxication. A diagnostic algorithm that focuses on medical history and biological specimen collection timing is herein proposed, in order to unify emergency approaches to the suspected poisoned child. (© 2024 American Academy of Forensic Sciences.) |
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فهرسة مساهمة: | Keywords: biological specimen; diagnostic algorithm; diagnostic workup; drug intoxication; pediatric accidental poisoning; toxicology |
المشرفين على المادة: | 40D3SCR4GZ (Buprenorphine) 0 (Narcotics) 0 (Analgesics, Opioid) |
تواريخ الأحداث: | Date Created: 20240401 Date Completed: 20240626 Latest Revision: 20240626 |
رمز التحديث: | 20240627 |
DOI: | 10.1111/1556-4029.15517 |
PMID: | 38558455 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1556-4029 |
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DOI: | 10.1111/1556-4029.15517 |