دورية أكاديمية
Neuropsychiatric Effects Associated with Opioid-Based Management for Palliative Care Patients.
| العنوان: | Neuropsychiatric Effects Associated with Opioid-Based Management for Palliative Care Patients. |
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| المؤلفون: | Kaye AD; Department of Anesthesiology, Louisiana State University Health Sciences Center at Shreveport, 1501 Kings Highway, Shreveport, LA, 71103, USA.; Department of Pharmacology, Louisiana State University Health Sciences Center at Shreveport, Toxicology, and Neurosciences, Shreveport, LA, 71103, USA., Dufrene K; School of Medicine, Louisiana State University Health Sciences Center Shreveport, Shreveport, LA, 71103, USA., Cooley J; School of Medicine, Louisiana State University Health Sciences Center Shreveport, Shreveport, LA, 71103, USA., Walker M; School of Medicine, Louisiana State University Health Sciences Center Shreveport, Shreveport, LA, 71103, USA., Shah S; School of Medicine, Louisiana State University Health Sciences Center Shreveport, Shreveport, LA, 71103, USA., Hollander A; School of Medicine, Louisiana State University Health Sciences Center Shreveport, Shreveport, LA, 71103, USA., Shekoohi S; Department of Anesthesiology, Louisiana State University Health Sciences Center at Shreveport, 1501 Kings Highway, Shreveport, LA, 71103, USA. sahar.shekoohi@lsuhs.edu., Robinson CL; Department of Anesthesiology, Critical Care, and Pain Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA. |
| المصدر: | Current pain and headache reports [Curr Pain Headache Rep] 2024 Jul; Vol. 28 (7), pp. 587-594. Date of Electronic Publication: 2024 Apr 02. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Current Science Inc Country of Publication: United States NLM ID: 100970666 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1534-3081 (Electronic) Linking ISSN: 15343081 NLM ISO Abbreviation: Curr Pain Headache Rep Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Philadelphia, PA : Current Science Inc., c2001- |
| مواضيع طبية MeSH: | Palliative Care*/methods , Analgesics, Opioid*/adverse effects , Analgesics, Opioid*/therapeutic use, Humans ; Opioid-Related Disorders/psychology |
| مستخلص: | Purpose of Review: The abundance of opioids administered in the palliative care setting that was once considered a standard of care is at present necessitating that providers evaluate patients for unintentional and deleterious symptomology related to aberrant opioid use and addiction. Polypharmacy with opioids is dynamic in affecting patients neurologically, and increased amounts of prescriptions have had inimical effects, not only for the individual, but also for their families and healthcare providers. The purpose of this review is to widen the perspective of opioid consequences and bring awareness to the numerous neuropsychiatric effects associated with the most commonly prescribed opioids for patients receiving palliative care. Recent Findings: Numerous clinical and research studies have found evidence in support for increased incidence of opioid usage and abuse as well as undesirable neurological outcomes. The most common and concerning effects of opioid usage in this setting are delirium and problematic drug-related behavioral changes such as deceitful behavior towards family and physicians, anger outbursts, overtaking of medications, and early prescription refill requests. Other neuropsychiatric effects detailed by recent studies include drug-seeking behavior, tolerance, dependence, addictive disorder, anxiety, substance use disorder, emotional distress, continuation of opioids to avoid opioid withdrawal syndrome, depression, and suicidal ideation. Opioid usage has detrimental and confounding effects that have been overlooked for many years by palliative care providers and patients receiving palliative care. It is necessary, even lifesaving, to be cognizant of potential neuropsychiatric effects that opioids can have on an individual, especially for those under palliative care. By having an increased understanding and awareness of potential opioid neuropsychiatric effects, patient quality of life can be improved, healthcare system costs can be decreased, and patient outcomes can be met and exceeded. (© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.) |
| فهرسة مساهمة: | Keywords: Fentanyl; Gabapentin; Hospice; Hydrocodone; Hydromorphone; Lorazepam; Morphine; Opioids; Oxycodone; Palliative care; Pregabalin; Tramadol |
| المشرفين على المادة: | 0 (Analgesics, Opioid) |
| تواريخ الأحداث: | Date Created: 20240402 Date Completed: 20240720 Latest Revision: 20240720 |
| رمز التحديث: | 20240721 |
| DOI: | 10.1007/s11916-024-01248-0 |
| PMID: | 38564124 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1534-3081 |
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| DOI: | 10.1007/s11916-024-01248-0 |