دورية أكاديمية
أعرض في EDS

Investigating the impact of insertion sequences and transposons in the genomes of the most significant phytopathogenic bacteria.

التفاصيل البيبلوغرافية
العنوان: Investigating the impact of insertion sequences and transposons in the genomes of the most significant phytopathogenic bacteria.
المؤلفون: Fernandes AS; Department of Microbiology, Federal University of Viçosa, Viçosa, Brazil., Campos KF; Department of Microbiology, Federal University of Viçosa, Viçosa, Brazil., de Assis JCS; Department of Microbiology, Federal University of Viçosa, Viçosa, Brazil., Gonçalves OS; Department of Microbiology, Federal University of Viçosa, Viçosa, Brazil., Queiroz MV; Department of Microbiology, Federal University of Viçosa, Viçosa, Brazil., Bazzolli DMS; Department of Microbiology, Federal University of Viçosa, Viçosa, Brazil., Santana MF; Department of Microbiology, Federal University of Viçosa, Viçosa, Brazil.
المصدر: Microbial genomics [Microb Genom] 2024 Apr; Vol. 10 (4).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Microbiology Society Country of Publication: England NLM ID: 101671820 Publication Model: Print Cited Medium: Internet ISSN: 2057-5858 (Electronic) Linking ISSN: 20575858 NLM ISO Abbreviation: Microb Genom Subsets: MEDLINE
أسماء مطبوعة: Publication: Oct. 2015- : [London] : Microbiology Society
Original Publication: [London] : Society for General Microbiology, [2015]-
مواضيع طبية MeSH: DNA Transposable Elements*/genetics , RNA, Small Untranslated*, Bacteria ; Gene Expression Profiling ; Host Specificity ; Plant Diseases
مستخلص: Genetic variability in phytopathogens is one of the main problems encountered for effective plant disease control. This fact may be related to the presence of transposable elements (TEs), but little is known about their role in host genomes. Here, we performed the most comprehensive analysis of insertion sequences (ISs) and transposons (Tns) in the genomes of the most important bacterial plant pathogens. A total of 35 692 ISs and 71 transposons were identified in 270 complete genomes. The level of pathogen-host specialization was found to be a significant determinant of the element distribution among the species. Some Tns were identified as carrying virulence factors, such as genes encoding effector proteins of the type III secretion system and resistance genes for the antimicrobial streptomycin. Evidence for IS-mediated ectopic recombination was identified in Xanthomonas genomes. Moreover, we found that IS elements tend to be inserted in regions near virulence and fitness genes, such ISs disrupting avirulence genes in X. oryzae genomes. In addition, transcriptome analysis under different stress conditions revealed differences in the expression of genes encoding transposases in the Ralstonia solanacearum , X. oryzae , and P. syringae species. Lastly, we also investigated the role of Tns in regulation via small noncoding regulatory RNAs and found these elements may target plant-cell transcriptional activators. Taken together, the results indicate that TEs may have a fundamental role in variability and virulence in plant pathogenic bacteria.
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فهرسة مساهمة: Keywords: phytopathogens; transposable genetic elements; virulence and genome evolution
المشرفين على المادة: 0 (DNA Transposable Elements)
0 (RNA, Small Untranslated)
تواريخ الأحداث: Date Created: 20240403 Date Completed: 20240404 Latest Revision: 20240516
رمز التحديث: 20240516
مُعرف محوري في PubMed: PMC11092175
DOI: 10.1099/mgen.0.001219
PMID: 38568199
قاعدة البيانات: MEDLINE
الوصف
تدمد:2057-5858
DOI:10.1099/mgen.0.001219