دورية أكاديمية
Anabolic steroids in livestock production: Background and implications for chemical food safety.
العنوان: | Anabolic steroids in livestock production: Background and implications for chemical food safety. |
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المؤلفون: | Chen T; Oniris, INRAE, LABERCA, Nantes 44300, France., Le Bizec B; Oniris, INRAE, LABERCA, Nantes 44300, France., Dervilly G; Oniris, INRAE, LABERCA, Nantes 44300, France. Electronic address: gaud.dervilly@oniris-nantes.fr. |
المصدر: | Steroids [Steroids] 2024 Jun; Vol. 206, pp. 109420. Date of Electronic Publication: 2024 Apr 03. |
نوع المنشور: | Journal Article; Review; Research Support, Non-U.S. Gov't |
اللغة: | English |
بيانات الدورية: | Publisher: Elsevier Country of Publication: United States NLM ID: 0404536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-5867 (Electronic) Linking ISSN: 0039128X NLM ISO Abbreviation: Steroids Subsets: MEDLINE |
أسماء مطبوعة: | Publication: New York Ny : Elsevier Original Publication: San Francisco. |
مواضيع طبية MeSH: | Livestock*/metabolism , Food Safety*, Animals ; Anabolic Agents/analysis ; Anabolic Agents/metabolism ; Humans ; Steroids/chemistry ; Steroids/analysis ; Steroids/metabolism ; Testosterone Congeners/analysis ; Testosterone Congeners/metabolism ; Food Contamination/analysis ; Anabolic Androgenic Steroids |
مستخلص: | The use of steroids in livestock animals is a source of concern for consumers because of the risks associated with the presence of their residues in foodstuffs of animal origin. Technological advances such as mass spectrometry have made it possible to play a fundamental role in controlling such practices, firstly for the discovery of marker metabolites but also for the monitoring of these compounds under the regulatory framework. Current control strategies rely on the monitoring of either the parent drug or its metabolites in various matrices of interest. As some of these steroids also have an endogenous status specific strategies have to be applied for control purposes. This review aims to provide a comprehensive and up-to-date knowledge of analytical strategies, whether targeted or non-targeted, and whether they focus on markers of exposure or effect in the specific context of chemical food safety regarding the use of anabolic steroids in livestock. The role of new approaches in data acquisition (e.g. ion mobility), processing and analysis, (e.g. molecular networking), is also discussed. Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2024 The Author(s). Published by Elsevier Inc. All rights reserved.) |
فهرسة مساهمة: | Keywords: Analytical strategies; Biomarkers; Food from animal origin; Mass spectrometry; Metabolomics; Steroids |
المشرفين على المادة: | 0 (Anabolic Agents) 0 (Steroids) 0 (Testosterone Congeners) 0 (Anabolic Androgenic Steroids) |
تواريخ الأحداث: | Date Created: 20240405 Date Completed: 20240510 Latest Revision: 20240510 |
رمز التحديث: | 20240511 |
DOI: | 10.1016/j.steroids.2024.109420 |
PMID: | 38580048 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1878-5867 |
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DOI: | 10.1016/j.steroids.2024.109420 |