دورية أكاديمية
أعرض في EDS

Autism in patients with eosinophilic gastrointestinal disease: A systematic review with meta-analysis.

التفاصيل البيبلوغرافية
العنوان: Autism in patients with eosinophilic gastrointestinal disease: A systematic review with meta-analysis.
المؤلفون: Lima RV; Department of Medicine, University of Fortaleza, Fortaleza, Ceara, Brazil., Muniz MCR; Department of Medicine, University of Fortaleza, Fortaleza, Ceara, Brazil., Barroso LL; Department of Medicine, University of Fortaleza, Fortaleza, Ceara, Brazil., Pinheiro MCA; Department of Medicine, University of Fortaleza, Fortaleza, Ceara, Brazil., Matos YMT; Department of Medicine, University of Fortaleza, Fortaleza, Ceara, Brazil., Nogueira SBR; Residency in Pediatrics at the School of Public Health, Fortaleza, Ceara, Brazil., Nogueira HBR; Department of Medicine, University of Fortaleza, Fortaleza, Ceara, Brazil.; Albert Sabin Children's Hospital, Fortaleza, Ceara, Brazil.
المصدر: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology [Pediatr Allergy Immunol] 2024 Apr; Vol. 35 (4), pp. e14122.
نوع المنشور: Meta-Analysis; Systematic Review; Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Blackwell Publishing Country of Publication: England NLM ID: 9106718 Publication Model: Print Cited Medium: Internet ISSN: 1399-3038 (Electronic) Linking ISSN: 09056157 NLM ISO Abbreviation: Pediatr Allergy Immunol
أسماء مطبوعة: Publication: <2010->: Oxford, UK : Blackwell Publishing
Original Publication: Copenhagen : Munksgaard, c1990-
مواضيع طبية MeSH: Eosinophilia*/epidemiology , Gastritis*/epidemiology , Gastritis*/immunology , Gastritis*/complications , Enteritis*/epidemiology , Enteritis*/complications, Humans ; Prevalence ; Autism Spectrum Disorder/epidemiology ; Autism Spectrum Disorder/complications ; Child ; Autistic Disorder/epidemiology
مستخلص: Purpose: Neurodevelopmental disorders, such as autism spectrum disorder (ASD), have been increasingly associated with eosinophilic gastrointestinal disorders (EGID). However, the relationship between these diseases remains unclear. We performed a systematic review with meta-analysis to address this issue.
Methods: The search was performed according to the PRISMA guidelines using descriptors for ASD and EGIDs from the MEDLINE, Embase, PsycInfo, LILACS, and Web of Science databases. Observational studies with the prevalence of ASD in any EGID were included. The study protocol was registered on the PROSPERO platform under the number CRD42023455177.
Results: The total dataset comprised 766,082 participants. The result of the single-arm meta-analysis showed an overall prevalence of ASD in the population with EGID of 21.59% (95% CI: 10.73-38.67). There was an association between EGID and ASD (OR: 3.44; 95% CI: 1.25-2.21), also significant when restricted only to EoE (OR: 3.70; 95% CI: 2.71-5.70).
Discussion: Recent studies have implicated the influence of an inadequate epithelial barrier integrity in the pathogenesis of several diseases. The role of this mechanism can be extended to situations beyond allergic reactions, including other conditions with underlying immunological mechanisms. Several diseases are potentially related to the systemic effect of bacterial translocation in tissues with defective epithelial barriers.
Conclusion: Our meta-analysis provides evidence that supports the consideration of EGID in patients with ASD and ASD in patients with EGID. Despite its limitations, the results should also be validated by future studies, preferably using multicenter prospective designs in populations with low referral bias.
(© 2024 European Academy of Allergy and Clinical Immunology and John Wiley & Sons Ltd.)
References: Gonsalves N. Eosinophilic gastrointestinal disorders. Clin Rev Allergy Immunol. 2019;57(2):272‐285.
Dellon ES. Eosinophilic gastrointestinal diseases beyond eosinophilic esophagitis. Am J Gastroenterol. 2022;117(5):697‐700.
Egan M, Furuta GT. Eosinophilic gastrointestinal diseases beyond eosinophilic esophagitis. Ann Allergy Asthma Immunol. 2018;121(2):162‐167.
Azzano P, Truc FV, Collardeau‐Frachon S, Lachaux A. Children with eosinophilic esophagitis in real life: 10 years' experience with a focus on allergic management. Allergol Immunopathol. 2020;48(3):244‐250.
Cavalli E, Brusaferro A, Pieri ES, et al. Eosinophilic esophagitis in children: doubts and future perspectives. J Transl Med. 2019;17(1):262.
Lucendo AJ, Molina‐Infante J, Arias Á, et al. Guidelines on eosinophilic esophagitis: evidence‐based statements and recommendations for diagnosis and management in children and adults. United European Gastroenterol J. 2017;5(3):335‐358.
Capucilli P, Cianferoni A, Grundmeier RW, Spergel JM. Comparison of comorbid diagnoses in children with and without eosinophilic esophagitis in a large population. Ann Allergy Asthma Immunol. 2018;121(6):711‐716.
Pesek RD, Rothenberg ME. Eosinophilic gastrointestinal disease below the belt. J Allergy Clin Immunol. 2020;145(1):87‐89.
Barni S, Arasi S, Mastrorilli C, et al. Pediatric eosinophilic esophagitis: a review for the clinician. Ital J Pediatr. 2021;47(1):230.
Leader G, Abberton C, Cunningham S, et al. Gastrointestinal symptoms in autism Spectrum disorder: a systematic review. Nutrients. 2022;14(7):1471.
Parmeggiani A. Gastrointestinal Disorders and Autism. Springer; 2014:2035‐2046.
Krigsman A, Walker SJ. Gastrointestinal disease in children with autism spectrum disorders: etiology or consequence? World J Psychiatry. 2021;11(9):605‐618.
Robinson R, Placone N, Katz M, Ornelas E. Upper gastrointestinal endoscopy with biopsy in paediatric feeding disorders. Acta Paediatr. 2021;110(10):2856‐2861.
Sohn JK, Barnes BH, Al‐Hazaymeh A, Sauer BG, McGowan EC. High prevalence of developmental disorders in pediatric eosinophilic esophagitis (EoE): a single‐center observational study. J Allergy Clin Immunol Pract. 2021;9(2):1032‐1034.
Taquette SR, Villela WV. Pesquisa qualitativa em medicina. Cien Saude Colet. 2017;22(1):4.
Lo CKL, Mertz D, Loeb M. Newcastle‐Ottawa scale: comparing reviewers' to authors' assessments. BMC Med Res Methodol. 2014;14(1):45.
Heifert TA, Susi A, Hisle‐Gorman E, et al. Feeding disorders in children with autism spectrum disorders are associated with eosinophilic esophagitis. J Pediatr Gastroenterol Nutr. 2016;63(4):69‐73.
Raffaele A, Vatta F, Votto M, et al. Eosinophilic colitis in children: a new and elusive enemy? Pediatr Surg Int. 2021;37(4):485‐490.
Votto M, Raffaele A, De Filippo M, et al. Eosinophilic gastrointestinal disorders in children and adolescents: a single‐center experience. Dig Liver Dis. 2022;54(2):214‐220.
Collins MH. Histopathology associated with eosinophilic gastrointestinal diseases. Immunol Allergy Clin North Am. 2009;29(1):109‐117.
Licari A, Votto M, D'Auria E, Castagnoli R, Caimmi SME, Marseglia GL. Eosinophilic gastrointestinal diseases in children: a practical review. Curr Pediatr Rev. 2020;16(2):106‐114.
Walker MM, Potter M, Talley NJ. Eosinophilic gastroenteritis and other eosinophilic gut diseases distal to the oesophagus. Lancet Gastroenterol Hepatol. 2018;3(4):271‐280.
Dellon ES, Gonsalves N, Abonia JP, et al. International consensus recommendations for Eosinophilic gastrointestinal disease nomenclature. Clin GastroenterolHepatol. 2022;20(11):2474‐2484.
Cianferoni A. Eosinophilic esophagitis and other eosinophilic disorders of the gastrointestinal tract. Pediatr Allergy Immunol. 2020 Feb;31(S24):25‐27.
Redd WD, Dellon ES. Eosinophilic gastrointestinal diseases beyond the esophagus: an evolving field and nomenclature. Gastroenterol Hepatol (N Y). 2022;18(9):522‐528.
Ferreira CT, Vieira MC, Furuta GT, de Barros FCLF, Chehade M. Eosinophilic esophagitis—where are we today? J Pediatr (Rio J). 2019;95(3):275‐281.
Hommeida S, Grothe RM, Hafed Y, et al. Assessing the incidence trend and characteristics of eosinophilic esophagitis in children in Olmsted County, Minnesota. Dis Esophagus. 2018;31(12):doy062.
Yousef E, Korotkaya Y, Simpson AB. Eosinophilic esophagitis in children: updates and practical aspects of management for allergists in a non‐tertiary care private practice setup. Allergy Asthma Proc. 2022;43(1):5‐11.
Akdis CA. Does the epithelial barrier hypothesis explain the increase in allergy, autoimmunity and other chronic conditions? Nat Rev Immunol. 2021;21:739‐751.
Akdis CA. The epithelial barrier hypothesis proposes a comprehensive understanding of the origins of allergic and other chronic noncommunicable diseases. J Allergy Clin Immunol. 2022;149(1):41‐44.
Izquierdo E, Rodriguez‐Coira J, Delgado‐Dolset M, Gomez‐Casado C, Barber D, Escribese MM. Epithelial barrier: protector and trigger of allergic Disorders. J Invest Allergol Clin Immunol. 2022;32(2):81‐96.
Kiykim A, Ogulur I, Yazici D, Cokugras H, Akdis M, Akdis CA. Epithelial barrier hypothesis and its comparison with the hygiene hypothesis. Turk Arch Pediatr. 2023;58(2):122‐128.
Celebi Sozener Z, Ozdel Ozturk B, Cerci P, et al. Epithelial barrier hypothesis: effect of the external exposome on the microbiome and epithelial barriers in allergic disease. Allergy. 2022;77(5):1418‐1449.
Yazici D, Ogulur I, Kucukkase O, et al. Epithelial barrier hypothesis and the development of allergic and autoimmune diseases. Allergo J Int. 2022;31(4):91‐102.
Makdissi S, Parsons B, Di Cara F. Towards early detection of neurodegenerative diseases: a gut feeling. Front Cell Dev Biol. 2023;11:1087091.
Fiorentino M, Sapone A, Senger S, et al. Blood–brain barrier and intestinal epithelial barrier alterations in autism spectrum disorders. Nol Autism. 2016;7(1):49.
Kushak RI, Buie TM, Murray KF, et al. Evaluation of intestinal function in children with autism and gastrointestinal symptoms. J Pediatr Gastroenterol Nutr. 2016;62(5):687‐691.
Lazaro CP, Ponde MP, Rodrigues LEA. Opioid peptides and gastrointestinal symptoms in autism spectrum disorders. Braz J Psychiatry. 2016;38(3):243‐246.
Madra M, Ringel R, Margolis KG. Gastrointestinal issues and autism spectrum disorder. Psychiatr Clin N Am. 2021;44(1):69‐81.
McElhanon BO, McCracken C, Karpen S, et al. Gastrointestinal symptoms in autism spectrum disorder: a meta‐analysis. Pediatrics. 2014;133(5):872‐883.
Al‐Biltagi M, Saeed NK, Qaraghuli S. Gastrointestinal disorders in children with autism: could artificial intelligence help? Artif Intell Gastroenterol. 2022;3(1):1‐12.
Ashwood P, Anthony A, Pellicer AA, Torrente F, Walker‐Smith JA, Wakefield AJ. Intestinal lymphocyte populations in children with regressive autism: evidence for extensive mucosal immunopathology. J Clin Immunol. 2003;23(6):504‐517.
Rodrigues M, D'Amico MFM, Patiño FRA, Barbieri D, Damião AOMC, Sipahi AM. Clinical manifestations, treatment, and outcomes of children and adolescents with eosinophilic esophagitis. J Pediatr (Rio J). 2013;89(2):197‐203.
Votto M, Naso M, Brambilla I, et al. Eosinophilic gastrointestinal diseases in inborn errors of immunity. J Clin Med. 2023;12(2):514.
Sohn J, Barnes B, Sauer B, McGowan E. Exploring the association between developmental Disorders and Eosinophilic esophagitis in children. J Allergy Clin Immunol. 2020;145(2):AB45.
فهرسة مساهمة: Keywords: autism spectrum disorder; eosinophilic colitis; eosinophilic esophagitis; eosinophilic gastrointestinal disorders
SCR Disease Name: Eosinophilic enteropathy
تواريخ الأحداث: Date Created: 20240406 Date Completed: 20240807 Latest Revision: 20240807
رمز التحديث: 20240808
DOI: 10.1111/pai.14122
PMID: 38581140
قاعدة البيانات: MEDLINE
الوصف
تدمد:1399-3038
DOI:10.1111/pai.14122