دورية أكاديمية
Self-healing hydrogel based on poly (vinyl alcohol)-poly (lysine)-gum arabic accelerates diabetic wound healing under photothermal sterilization.
| العنوان: | Self-healing hydrogel based on poly (vinyl alcohol)-poly (lysine)-gum arabic accelerates diabetic wound healing under photothermal sterilization. |
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| المؤلفون: | Lu M; School of Chemistry and Materials Engineering, Huizhou University, Huizhou 516007, PR China; Guangdong Engineering & Technology Research Centre of Graphene-like Materials and Products, Department of Chemistry, College of Chemistry and Materials Science, Jinan University, Guangzhou 510632, PR China., Peng W; Guangdong Engineering & Technology Research Centre of Graphene-like Materials and Products, Department of Chemistry, College of Chemistry and Materials Science, Jinan University, Guangzhou 510632, PR China., Kang W; Guangdong Engineering & Technology Research Centre of Graphene-like Materials and Products, Department of Chemistry, College of Chemistry and Materials Science, Jinan University, Guangzhou 510632, PR China., Huang L; Guangdong Engineering & Technology Research Centre of Graphene-like Materials and Products, Department of Chemistry, College of Chemistry and Materials Science, Jinan University, Guangzhou 510632, PR China., Zhang J; Guangdong Engineering & Technology Research Centre of Graphene-like Materials and Products, Department of Chemistry, College of Chemistry and Materials Science, Jinan University, Guangzhou 510632, PR China., Tan S; Guangdong Engineering & Technology Research Centre of Graphene-like Materials and Products, Department of Chemistry, College of Chemistry and Materials Science, Jinan University, Guangzhou 510632, PR China. Electronic address: tsztan@jnu.edu.cn., Huo DL; Guangdong Engineering & Technology Research Centre of Graphene-like Materials and Products, Department of Chemistry, College of Chemistry and Materials Science, Jinan University, Guangzhou 510632, PR China. Electronic address: 1436852199@qq.com., Chen H; School of Chemistry and Pharmaceutical Science, Guangxi Normal University, Guilin 541004, PR China. Electronic address: chenhf1968@163.com. |
| المصدر: | International journal of biological macromolecules [Int J Biol Macromol] 2024 May; Vol. 266 (Pt 2), pp. 131395. Date of Electronic Publication: 2024 Apr 04. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Amsterdam : Elsevier Original Publication: Guildford, Eng., IPC Science and Technology Press. |
| مواضيع طبية MeSH: | Wound Healing*/drug effects , Polyvinyl Alcohol*/chemistry , Hydrogels*/chemistry , Hydrogels*/pharmacology , Polylysine*/chemistry , Polylysine*/pharmacology , Gum Arabic*/chemistry , Gum Arabic*/pharmacology, Animals ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry ; Diabetes Mellitus, Experimental ; Rats ; Sterilization/methods ; Male ; Mice ; Graphite/chemistry ; Graphite/pharmacology |
| مستخلص: | Diabetic wounds are a significant clinical challenge. Developing effective antibacterial dressings is crucial for preventing wound ulcers caused by bacterial infections. In this study, a self-healing antibacterial hydrogel (polyvinyl alcohol (PVA)-polylysine-gum arabic, PLG hydrogels) with near-infrared photothermal response was prepared by linking PVA and a novel polysaccharide-amino acid compound (PG) through borate bonding combined with freeze-thaw cycling. Subsequently, the hydrogel was modified by incorporating inorganic nanoparticles (modified graphene oxide (GM)). The experimental results showed that the PLGM Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2024 Elsevier B.V. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Antibacterial; Diabetic wounds; Self-healing hydrogel |
| المشرفين على المادة: | 9002-89-5 (Polyvinyl Alcohol) 0 (Hydrogels) 25104-18-1 (Polylysine) 9000-01-5 (Gum Arabic) 0 (Anti-Bacterial Agents) 7782-42-5 (Graphite) 0 (graphene oxide) |
| تواريخ الأحداث: | Date Created: 20240406 Date Completed: 20240430 Latest Revision: 20240430 |
| رمز التحديث: | 20240430 |
| DOI: | 10.1016/j.ijbiomac.2024.131395 |
| PMID: | 38582460 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1879-0003 |
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| DOI: | 10.1016/j.ijbiomac.2024.131395 |