دورية أكاديمية
Severe hemolysis, elevated liver enzymes, and low platelet syndrome requiring differentiation of thrombotic microangiopathy: Four cases from a nationwide survey in Japan.
| العنوان: | Severe hemolysis, elevated liver enzymes, and low platelet syndrome requiring differentiation of thrombotic microangiopathy: Four cases from a nationwide survey in Japan. |
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| المؤلفون: | Komatsu R; Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan., Mimura K; Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan., Matsuyama T; Department of Obstetrics and Gynecology, Osaka Saiseikai Nakatsu Hospital, Osaka-shi, Osaka, Japan., Kawanishi Y; Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan., Nakamura H; Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan., Tomimatsu T; Department of Nursing, Faculty of Global Nursing, Otemae University, Osaka-shi, Osaka, Japan., Endo M; Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan., Kimura T; Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan. |
| المصدر: | The journal of obstetrics and gynaecology research [J Obstet Gynaecol Res] 2024 Jul; Vol. 50 (7), pp. 1258-1262. Date of Electronic Publication: 2024 Apr 08. |
| نوع المنشور: | Case Reports; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley on behalf of the Japan Society of Obstetrics and Gynecology] Country of Publication: Australia NLM ID: 9612761 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1447-0756 (Electronic) Linking ISSN: 13418076 NLM ISO Abbreviation: J Obstet Gynaecol Res Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: [Melbourne, Vic. : Wiley on behalf of the Japan Society of Obstetrics and Gynecology] Original Publication: Tokyo : University of Tokyo Press, c1996- |
| مواضيع طبية MeSH: | HELLP Syndrome*/diagnosis , Thrombotic Microangiopathies*/diagnosis , Thrombotic Microangiopathies*/epidemiology, Humans ; Female ; Japan/epidemiology ; Pregnancy ; Adult ; Diagnosis, Differential ; Plasma Exchange |
| مستخلص: | Severe cases of hemolysis, elevated liver enzymes, and low platelet (HELLP) syndrome requiring plasma exchange or dialysis should be differentiated from other thrombotic microangiopathy (TMA) and treated appropriately. To evaluate the prevalence and clinical characteristics of such cases in Japan, a questionnaire-based survey was conducted among obstetricians who are members of the Perinatal Research Network Group in Japan. There were a total of 335 cases of HELLP syndrome over a 3-year period in the 48 facilities that responded to the survey. Four patients required plasma exchange or dialysis, of which two were diagnosed with atypical hemolytic uremic syndrome and two with TMA secondary to systemic lupus erythematosus. Although such severe HELLP syndrome is rare, identifying the clinical features and making accurate differential diagnosis are critical for optimal clinical outcomes for mothers and neonates. (© 2024 The Authors. Journal of Obstetrics and Gynaecology Research published by John Wiley & Sons Australia, Ltd on behalf of Japan Society of Obstetrics and Gynecology.) |
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| معلومات مُعتمدة: | Perinatal Research Network Group in Japan; JP21K09447 MEXT KAKENHI; JP20K09618 MEXT KAKENHI |
| فهرسة مساهمة: | Keywords: HELLP syndrome; atypical hemolytic uremic syndrome; pregnancy; pre‐eclampsia; thrombotic microangiopathy |
| تواريخ الأحداث: | Date Created: 20240408 Date Completed: 20240708 Latest Revision: 20240708 |
| رمز التحديث: | 20240709 |
| DOI: | 10.1111/jog.15949 |
| PMID: | 38589336 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1447-0756 |
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| DOI: | 10.1111/jog.15949 |