دورية أكاديمية
Characteristics and Related Factors of Bacterial Infection Among Patients With Cirrhosis.
العنوان: | Characteristics and Related Factors of Bacterial Infection Among Patients With Cirrhosis. |
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المؤلفون: | Lan NN; Department of Biochemistry, Hanoi Medical University, Hanoi, Vietnam., Lieu DQ; Department of Internal Medicine, Hanoi Medical University Hospital, Hanoi, Vietnam., Anh TN; Department of Internal Medicine, Hanoi Medical University Hospital, Hanoi, Vietnam.; Department of Internal Medicine, Hanoi Medical University, Hanoi, Vietnam., Thuong LH; Department of Internal Medicine, Hanoi Medical University, Hanoi, Vietnam., Tuong TK; Department of Internal Medicine, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam., Bang MH; Department of Gastroenterology, 108 Military Central Hospital, Hanoi, Vietnam. |
المصدر: | Materia socio-medica [Mater Sociomed] 2024; Vol. 36 (1), pp. 90-96. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Academy of Medical Sciences of Bosnia & Herzegovina Country of Publication: Bosnia and Herzegovina NLM ID: 101281595 Publication Model: Print Cited Medium: Print ISSN: 1512-7680 (Print) Linking ISSN: 15127680 NLM ISO Abbreviation: Mater Sociomed Subsets: PubMed not MEDLINE |
أسماء مطبوعة: | Publication: Sarajevo, Bosnia and Herzegovina : Academy of Medical Sciences of Bosnia & Herzegovina Original Publication: Sarajevo : Udruženje za socijalnu medicinu-javno zdravstvo BiH |
مستخلص: | Background: Infection causes cirrhosis to decompensate, affecting liver function and resulting in several complications, including esophageal variceal hemorrhage, hepatic encephalopathy, and hepatorenal syndrome. Objective: This study aimed to identify the prevalence, essential features, and related factors of bacterial infection among patients with cirrhosis in Vietnam. Methods: This retrospective study included 317 patients diagnosed with cirrhosis, who were divided into two groups: group 1 including 125 patients with bacterial infection and group 2 including 192 patients without bacterial infection. Infection was diagnosed on the basis of its localization. Results: Spontaneous bacterial peritonitis (SBP; 31.2%) and pneumonia (28.8%) were the most common infections identified. The procalcitonin (PCT) level had a strong diagnostic value with an area under the curve value of 0.868. The most common type of gram-negative bacteria was Escherichia coli, while the gram-positive bacteria seen were Staphylococcus, Enterococcus, and Streptococcus among the patients with infection. In the logistic regression analysis, Child-Pugh class B and C (p<0.001, OR=4.14, CI=1.90-9.03; OR=4.76, CI=2.03-11.16, respectively) and the presence of acute kidney injury (p=0.009, OR=2.57, CI=1.27-5.22) and gastrointestinal hemorrhage (p=0.035, OR=0.39, CI=0.16-0.94) significantly differed between the groups. Conclusion: The most prevalent type of bacterial infection in patients with cirrhosis is SBP, with gram-negative bacteria being the most common cause. The PCT level is useful in identifying infection in patients with cirrhosis. Decompensated cirrhosis is linked to a higher risk of infection. Competing Interests: There are no conflicts of interest. (© 2024 Nguyen-Thi Ngoc Lan, Dau Quang Lieu, Tran Ngoc Anh, Le Hoai Thuong, Tran-Thi Khanh Tuong, Mai Hong Bang.) |
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فهرسة مساهمة: | Keywords: Bacterial infection; Cirrhosis; Procalcitonin |
تواريخ الأحداث: | Date Created: 20240409 Latest Revision: 20240410 |
رمز التحديث: | 20240410 |
مُعرف محوري في PubMed: | PMC10999149 |
DOI: | 10.5455/msm.2024.36.90-96 |
PMID: | 38590588 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1512-7680 |
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DOI: | 10.5455/msm.2024.36.90-96 |