دورية أكاديمية
أعرض في EDS

Characteristics and Related Factors of Bacterial Infection Among Patients With Cirrhosis.

التفاصيل البيبلوغرافية
العنوان: Characteristics and Related Factors of Bacterial Infection Among Patients With Cirrhosis.
المؤلفون: Lan NN; Department of Biochemistry, Hanoi Medical University, Hanoi, Vietnam., Lieu DQ; Department of Internal Medicine, Hanoi Medical University Hospital, Hanoi, Vietnam., Anh TN; Department of Internal Medicine, Hanoi Medical University Hospital, Hanoi, Vietnam.; Department of Internal Medicine, Hanoi Medical University, Hanoi, Vietnam., Thuong LH; Department of Internal Medicine, Hanoi Medical University, Hanoi, Vietnam., Tuong TK; Department of Internal Medicine, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam., Bang MH; Department of Gastroenterology, 108 Military Central Hospital, Hanoi, Vietnam.
المصدر: Materia socio-medica [Mater Sociomed] 2024; Vol. 36 (1), pp. 90-96.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Academy of Medical Sciences of Bosnia & Herzegovina Country of Publication: Bosnia and Herzegovina NLM ID: 101281595 Publication Model: Print Cited Medium: Print ISSN: 1512-7680 (Print) Linking ISSN: 15127680 NLM ISO Abbreviation: Mater Sociomed Subsets: PubMed not MEDLINE
أسماء مطبوعة: Publication: Sarajevo, Bosnia and Herzegovina : Academy of Medical Sciences of Bosnia & Herzegovina
Original Publication: Sarajevo : Udruženje za socijalnu medicinu-javno zdravstvo BiH
مستخلص: Background: Infection causes cirrhosis to decompensate, affecting liver function and resulting in several complications, including esophageal variceal hemorrhage, hepatic encephalopathy, and hepatorenal syndrome. Objective: This study aimed to identify the prevalence, essential features, and related factors of bacterial infection among patients with cirrhosis in Vietnam.
Methods: This retrospective study included 317 patients diagnosed with cirrhosis, who were divided into two groups: group 1 including 125 patients with bacterial infection and group 2 including 192 patients without bacterial infection. Infection was diagnosed on the basis of its localization.
Results: Spontaneous bacterial peritonitis (SBP; 31.2%) and pneumonia (28.8%) were the most common infections identified. The procalcitonin (PCT) level had a strong diagnostic value with an area under the curve value of 0.868. The most common type of gram-negative bacteria was Escherichia coli, while the gram-positive bacteria seen were Staphylococcus, Enterococcus, and Streptococcus among the patients with infection. In the logistic regression analysis, Child-Pugh class B and C (p<0.001, OR=4.14, CI=1.90-9.03; OR=4.76, CI=2.03-11.16, respectively) and the presence of acute kidney injury (p=0.009, OR=2.57, CI=1.27-5.22) and gastrointestinal hemorrhage (p=0.035, OR=0.39, CI=0.16-0.94) significantly differed between the groups.
Conclusion: The most prevalent type of bacterial infection in patients with cirrhosis is SBP, with gram-negative bacteria being the most common cause. The PCT level is useful in identifying infection in patients with cirrhosis. Decompensated cirrhosis is linked to a higher risk of infection.
Competing Interests: There are no conflicts of interest.
(© 2024 Nguyen-Thi Ngoc Lan, Dau Quang Lieu, Tran Ngoc Anh, Le Hoai Thuong, Tran-Thi Khanh Tuong, Mai Hong Bang.)
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فهرسة مساهمة: Keywords: Bacterial infection; Cirrhosis; Procalcitonin
تواريخ الأحداث: Date Created: 20240409 Latest Revision: 20240410
رمز التحديث: 20240410
مُعرف محوري في PubMed: PMC10999149
DOI: 10.5455/msm.2024.36.90-96
PMID: 38590588
قاعدة البيانات: MEDLINE
الوصف
تدمد:1512-7680
DOI:10.5455/msm.2024.36.90-96