دورية أكاديمية
أعرض في EDS

Effects of 12 weeks of inspiratory muscle training and whole body vibration on the inflammatory profile, BDNF and muscular system in pre-frail elderly women: A randomized controlled trial.

التفاصيل البيبلوغرافية
العنوان: Effects of 12 weeks of inspiratory muscle training and whole body vibration on the inflammatory profile, BDNF and muscular system in pre-frail elderly women: A randomized controlled trial.
المؤلفون: de Souza HCM; Postgraduate Program of Biology Applied to Health, Federal University of Pernambuco, Recife, Pernambuco, Brazil; Hospital das Clínicas de Pernambuco - Empresa Brasileira de Serviços Hospitalares (HCPE-EBSERH), Federal University of Pernambuco, Recife, Brazil; Laboratory of Cardiopulmonary Physiotherapy, Department of Physiotherapy, Federal University of Pernambuco, Recife, Brazil. Electronic address: helgamuniz@yahoo.com.br., Pessoa MF; Postgraduate Program of Biology Applied to Health, Federal University of Pernambuco, Recife, Pernambuco, Brazil; Laboratory of Cardiopulmonary Physiotherapy, Department of Physiotherapy, Federal University of Pernambuco, Recife, Brazil., Clemente RDS; Laboratory of Cardiopulmonary Physiotherapy, Department of Physiotherapy, Federal University of Pernambuco, Recife, Brazil., da Silva AV; Laboratory of Cardiopulmonary Physiotherapy, Department of Physiotherapy, Federal University of Pernambuco, Recife, Brazil., Cardoso PRG; Laboratory of Immunomodulation and New Approaches, Federal University of Pernambuco, Recife, Brazil., Fernandes J; Laboratory of Physiotherapy and Collective Health, Department of Physiotherapy, Federal University of Pernambuco, Recife, Brazil., Dornelas de Andrade A; Postgraduate Program of Biology Applied to Health, Federal University of Pernambuco, Recife, Pernambuco, Brazil; Laboratory of Cardiopulmonary Physiotherapy, Department of Physiotherapy, Federal University of Pernambuco, Recife, Brazil. Electronic address: armeledornelas@yahoo.com.
المصدر: Archives of gerontology and geriatrics [Arch Gerontol Geriatr] 2024 Aug; Vol. 123, pp. 105421. Date of Electronic Publication: 2024 Mar 24.
نوع المنشور: Journal Article; Randomized Controlled Trial
اللغة: English
بيانات الدورية: Publisher: Elsevier Biomedical Press Country of Publication: Netherlands NLM ID: 8214379 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-6976 (Electronic) Linking ISSN: 01674943 NLM ISO Abbreviation: Arch Gerontol Geriatr Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Amsterdam : Elsevier Biomedical Press, c1982-
مواضيع طبية MeSH: Brain-Derived Neurotrophic Factor*/blood , Vibration*/therapeutic use , Breathing Exercises*/methods , Respiratory Muscles*/physiology, Humans ; Female ; Aged ; Double-Blind Method ; Aged, 80 and over ; Muscle Strength/physiology ; Middle Aged ; Biomarkers/blood ; Inflammation ; Body Composition/physiology
مستخلص: Aim: to investigate the effects of the whole body vibration (WBV) and inspiratory muscle training (IMT) on the inflammatory profile and in muscle mass and strength in pre-frail older women.
Methods: this study was a randomized double-blind trial. Forty two older women aged 60-80 years were randomly allocated to IMT + WBV (G1), IMTsham + WBV (G2) or Sham groups (G3). During 12 weeks G1 received both trainings, whereas G2 received WBV alone and G3 received IMT with a low fixed load and were positioned at the vibratory platform without therapeutic effect. Participants were evaluated before and after the intervention for the following outcomes: Brain-derived neurotrophic factor (BDNF) and inflammatory biomarkers (IB), respiratory (RT) and quadriceps thickness (QT) and diaphragmatic mobility (DM) using muscle ultrasound, body composition (BC) using a bioelectrical impedance scale and inspiratory muscle strength (IMS).
Results: after the training, G1 (114.93 ± 21.29) improved IMS (p<0.005) compared with G2 (91.29 ± 23.10) and G3 (85.21 ± 27.02). There was also a significant improve on time of the DM (p<0.001) and RT (p=0.006) for G1 (8.59 ± 3.55 and 11.11 ± 12.66) compared with G2 (1.05 ± 3.09 and 1.10 ± 10.60) and G3 (0.40 ± 2.29 and -1.85 ± 7.45). BDNF, IB, QT and BC were similar between groups.
Conclusions: IMT associated with WBV is effective to improve in increasing IMS, RT and DM in pre-frail older women. However, these interventions do not modify BDNF, IB, QT or BC in this population.
Competing Interests: Declaration of competing interest None.
(Copyright © 2024 Elsevier B.V. All rights reserved.)
فهرسة مساهمة: Keywords: Biomarkers; Exercise; Frailty; Muscle mass; Respiratory muscles; Ultrasound
المشرفين على المادة: 0 (Brain-Derived Neurotrophic Factor)
0 (Biomarkers)
7171WSG8A2 (BDNF protein, human)
تواريخ الأحداث: Date Created: 20240409 Date Completed: 20240604 Latest Revision: 20240717
رمز التحديث: 20240718
DOI: 10.1016/j.archger.2024.105421
PMID: 38593699
قاعدة البيانات: MEDLINE
الوصف
تدمد:1872-6976
DOI:10.1016/j.archger.2024.105421