دورية أكاديمية
أعرض في EDS

Outcome of illuminated microcatheter-assisted circumferential trabeculotomy following failed angle surgery in PAX6 aniridic glaucoma: a case report and literature review.

التفاصيل البيبلوغرافية
العنوان: Outcome of illuminated microcatheter-assisted circumferential trabeculotomy following failed angle surgery in PAX6 aniridic glaucoma: a case report and literature review.
المؤلفون: Wu T; Department of Ophthalmology, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China.; Beijing Key Laboratory of Restoration of Damaged Ocular nerve, Peking University Third Hospital, Beijing, China., Cui C; Department of Ophthalmology, Handan Central Hospital, Handan, Hebei, China., Li Y; Department of Ophthalmology, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China.; Beijing Key Laboratory of Restoration of Damaged Ocular nerve, Peking University Third Hospital, Beijing, China., Hong Y; Department of Ophthalmology, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China. drhongying@bjmu.edu.cn.; Beijing Key Laboratory of Restoration of Damaged Ocular nerve, Peking University Third Hospital, Beijing, China. drhongying@bjmu.edu.cn., Zhang C; Department of Ophthalmology, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China. zhangc1@yahoo.com.; Beijing Key Laboratory of Restoration of Damaged Ocular nerve, Peking University Third Hospital, Beijing, China. zhangc1@yahoo.com.
المصدر: BMC ophthalmology [BMC Ophthalmol] 2024 Apr 09; Vol. 24 (1), pp. 157. Date of Electronic Publication: 2024 Apr 09.
نوع المنشور: Review; Case Reports; Journal Article
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100967802 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2415 (Electronic) Linking ISSN: 14712415 NLM ISO Abbreviation: BMC Ophthalmol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BioMed Central, [2001-
مواضيع طبية MeSH: Aniridia* , Glaucoma*/diagnosis , Glaucoma*/surgery , Trabeculectomy*/methods, Humans ; Male ; Young Adult ; Follow-Up Studies ; Gonioscopy ; Intraocular Pressure ; PAX6 Transcription Factor ; Retrospective Studies ; Treatment Outcome
مستخلص: Background: Aniridia is a rare eye disorder with a high incidence of glaucoma, and surgical intervention is often needed to control the intraocular pressure (IOP). Here, we reported a case of illuminated microcatheter-assisted circumferential trabeculotomy (MAT) performed on an aniridic glaucoma patient following a previous failed angle surgery. The surgical procedures for aniridic glaucoma were also reviewed.
Case Presentation: A 21-year-old man, diagnosed with aniridic glaucoma, came to our hospital consulting for the poor control of left eye's IOP despite receiving goniotomy surgery 3 years ago. The IOP was 26 mmHg with maximum topical antiglaucoma eyedrops. The central cornea was opaque and the majority of iris was absent. The gonioscopy and ultrasound biomicroscopy (UBM) demonstrated that 360° anterior chamber angle was closed. The whole exome sequencing of peripheral blood confirmed a 13.39 Mb copy number loss at chromosome 11p15.1p13, containing PAX6 and WT1 gene. The 360° MAT surgery was performed on his left eye. At 1-year follow-up, the IOP was 19mmHg with 2 kinds of topical antiglaucoma medications, and the postoperative UBM demonstrated the successful incision of the anterior chamber angle.
Conclusions: The case presented here exhibited a case of aniridic glaucoma treated by MAT surgery. The MAT surgery may be an effective option for IOP control in aniridic glaucoma patients following a previous failed angle surgery.
(© 2024. The Author(s).)
References: Int Ophthalmol. 2014 Aug;34(4):753-60. (PMID: 24136034)
Trans Am Ophthalmol Soc. 1974;72:207-28. (PMID: 4462243)
J AAPOS. 2012 Oct;16(5):424-7. (PMID: 23084377)
Front Pediatr. 2021 Dec 14;9:733018. (PMID: 34970513)
Acta Ophthalmol. 2008 Nov;86(7):708-15. (PMID: 18937825)
Arch Ophthalmol. 1999 Sep;117(9):1144-8. (PMID: 10496385)
Int Ophthalmol Clin. 2008 Spring;48(2):79-85. (PMID: 18427263)
Ophthalmology. 1997 Dec;104(12):2121-5. (PMID: 9400774)
Eur J Ophthalmol. 2012 Jan-Feb;22(1):104-10. (PMID: 22167549)
Surv Ophthalmol. 2021 Nov-Dec;66(6):1031-1050. (PMID: 33675823)
Ophthalmology. 1998 Oct;105(10):1921-6; discussion 1926-7. (PMID: 9787365)
Saudi J Ophthalmol. 2022 Feb 18;35(2):117-121. (PMID: 35391820)
Curr Opin Ophthalmol. 2017 Sep;28(5):436-447. (PMID: 28598868)
Ophthalmology. 1998 Jan;105(1):101-11. (PMID: 9442785)
Biomed Res Int. 2020 Nov 04;2020:3716859. (PMID: 33204692)
Am J Ophthalmol. 2021 Jul;227:173-181. (PMID: 33737035)
Am J Ophthalmol. 2023 Dec;256:46-54. (PMID: 37516402)
Arch Ophthalmol. 1992 Apr;110(4):503-5. (PMID: 1562257)
Trans Am Ophthalmol Soc. 1986;84:59-70. (PMID: 3590479)
Am J Hum Genet. 1992 Dec;51(6):1286-94. (PMID: 1334370)
Acta Ophthalmol. 2017 Dec;95(8):e713-e719. (PMID: 28266150)
Eur J Hum Genet. 2012 Oct;20(10):1011-7. (PMID: 22692063)
معلومات مُعتمدة: BYSYZHKC2021108 Innovation & Transfer Fund of Peking University Third Hospital; 81970798 National Natural Science Foundation of China
فهرسة مساهمة: Keywords: PAX6; Aniridia; Aniridic glaucoma; Case report; Illuminated microcatheter-assisted circumferential trabeculotomy
المشرفين على المادة: 0 (PAX6 protein, human)
0 (PAX6 Transcription Factor)
تواريخ الأحداث: Date Created: 20240409 Date Completed: 20240411 Latest Revision: 20240424
رمز التحديث: 20240424
مُعرف محوري في PubMed: PMC11005255
DOI: 10.1186/s12886-024-03425-6
PMID: 38594720
قاعدة البيانات: MEDLINE
الوصف
تدمد:1471-2415
DOI:10.1186/s12886-024-03425-6