دورية أكاديمية
أعرض في EDS

Isolated gastric varices associated with antiphospholipid syndrome and protein S deficiency: a case report and review of the literature.

التفاصيل البيبلوغرافية
العنوان: Isolated gastric varices associated with antiphospholipid syndrome and protein S deficiency: a case report and review of the literature.
المؤلفون: Li X; Department of Gastroenterology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China., Wu J; Department of Gastroenterology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China., Fang F; Department of Gastroenterology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China., Liu Y; Department of Gastroenterology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China., Jiang W; Department of Gastroenterology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China., Li G; Department of Gastroenterology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China., Song J; Department of Gastroenterology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.
المصدر: The Journal of international medical research [J Int Med Res] 2024 Apr; Vol. 52 (4), pp. 3000605241240579.
نوع المنشور: Review; Case Reports; Journal Article
اللغة: English
بيانات الدورية: Publisher: Sage Publications Country of Publication: England NLM ID: 0346411 Publication Model: Print Cited Medium: Internet ISSN: 1473-2300 (Electronic) Linking ISSN: 03000605 NLM ISO Abbreviation: J Int Med Res Subsets: MEDLINE
أسماء مطبوعة: Publication: Nov. 2012- : London : Sage Publications
Original Publication: Northampton, Eng., Cambridge Medical Publications ltd.
مواضيع طبية MeSH: Esophageal and Gastric Varices*/complications , Esophageal and Gastric Varices*/diagnosis , Antiphospholipid Syndrome*/complications , Antiphospholipid Syndrome*/diagnosis , Protein S Deficiency*/complications , Vascular Diseases*/complications, Female ; Humans ; Adult ; Gastrointestinal Hemorrhage/etiology
مستخلص: The mortality rate of gastric varices bleeding can reach 20% within 6 weeks. Isolated gastric varices (IGVs) refer to gastric varices without esophageal varices and typically arise as a common complication of left portal hypertension. Although IGVs commonly form in the setting of splenic vein occlusion, the combination of antiphospholipid syndrome and protein S deficiency leading to splenic vein occlusion is rare. We herein present a case of a 28-year-old woman with intermittent epigastric pain and melena. She was diagnosed with antiphospholipid syndrome based on the triad of pregnancy morbidity, unexplained venous occlusion, and positive lupus anticoagulant. Laparoscopic splenectomy and pericardial devascularization were performed for the treatment of IGVs. During the 6-month postoperative follow-up, repeated endoscopy and contrast-enhanced computed tomography revealed disappearance of the IGVs. This is the first description of splenic vein occlusion associated with both antiphospholipid syndrome and protein S deficiency. We also provide a review of the etiology, clinical manifestations, diagnosis, and treatment methods of IGVs.
Competing Interests: Declaration of conflicting interestThe authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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فهرسة مساهمة: Keywords: Isolated gastric varices; antiphospholipid syndrome; case report; hemorrhage; left-sided portal hypertension; protein S deficiency; splenic vein occlusion
تواريخ الأحداث: Date Created: 20240411 Date Completed: 20240415 Latest Revision: 20240415
رمز التحديث: 20240415
مُعرف محوري في PubMed: PMC11010754
DOI: 10.1177/03000605241240579
PMID: 38603605
قاعدة البيانات: MEDLINE
الوصف
تدمد:1473-2300
DOI:10.1177/03000605241240579