دورية أكاديمية

Giant cerebral cavernous malformation in a newborn: a rare case report and review of literature.

التفاصيل البيبلوغرافية
العنوان: Giant cerebral cavernous malformation in a newborn: a rare case report and review of literature.
المؤلفون: Moreno I; Department of Pediatric Neurosurgery, Hospital del Niño Francisco Icaza Bustamante, Guayaquil, Ecuador., Scalia G; Department of Neurosurgery, Garibaldi Hospital, Catania, Italy., Umana GE; Department of Neurosurgery, Cannizaro Hospital, Catania, Italy., Soriano C; Department of Pediatric, Hospital Del Niño Francisco Icaza Bustamante, Guayaquil, Ecuador., Alcivar I; Department of Pediatric, Hospital Del Niño Francisco Icaza Bustamante, Guayaquil, Ecuador., Chaurasia B; Department of Neurosurgery, Neurosurgery Clinic, Birgunj, Nepal. trozexa@gmail.com.
المصدر: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery [Childs Nerv Syst] 2024 Jul; Vol. 40 (7), pp. 2215-2221. Date of Electronic Publication: 2024 Apr 12.
نوع المنشور: Journal Article; Case Reports; Review
اللغة: English
بيانات الدورية: Publisher: Springer International Country of Publication: Germany NLM ID: 8503227 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1433-0350 (Electronic) Linking ISSN: 02567040 NLM ISO Abbreviation: Childs Nerv Syst Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Berlin : Springer International, c1985-
مواضيع طبية MeSH: Hemangioma, Cavernous, Central Nervous System*/surgery , Hemangioma, Cavernous, Central Nervous System*/diagnostic imaging , Hemangioma, Cavernous, Central Nervous System*/pathology, Female ; Humans ; Male ; Magnetic Resonance Imaging ; Infant
مستخلص: Background: Cavernous malformations (CMs), also known as cavernomas or cavernous angiomas, are vascular malformations characterized by sinusoidal spaces lined by endothelial cells. Giant CMs (GCMs) are extremely rare, with limited understanding of their presentation and management. We present a case of symptomatic GCM in a newborn and review the literature on this rare entity.
Case Description: A 1-month-old newborn presented with focal seizures and signs of increased intracranial pressure. Imaging revealed a massive right frontal-parietal GCM, prompting surgical resection. Histopathological examination confirmed the diagnosis of cerebral cavernous malformation. The patient recovered well postoperatively with no neurological deficits.
Conclusions: GCMs are exceedingly rare in children and have not been reported in newborns until now. Symptoms typically include seizures and mass effects. Gross total resection is the standard treatment, offering favorable outcomes. Further research is needed to understand the natural history and optimal management of GCMs, particularly in newborns, emphasizing the importance of heightened clinical awareness for timely diagnosis and appropriate management.
(© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
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فهرسة مساهمة: Keywords: Cavernous malformation; Giant cerebral cavernous malformation; Histopathology; Intracranial hemorrhage; Newborn; Pediatric neurosurgery; Seizures; Surgical resection
تواريخ الأحداث: Date Created: 20240412 Date Completed: 20240615 Latest Revision: 20240621
رمز التحديث: 20240621
DOI: 10.1007/s00381-024-06401-z
PMID: 38607549
قاعدة البيانات: MEDLINE
الوصف
تدمد:1433-0350
DOI:10.1007/s00381-024-06401-z