دورية أكاديمية
Iron status in Dutch and Finnish blood donor and general populations: A cross-cohort comparison study.
| العنوان: | Iron status in Dutch and Finnish blood donor and general populations: A cross-cohort comparison study. |
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| المؤلفون: | Karregat JHM; Donor Studies, Department of Donor Medicine Research, Sanquin Research, Amsterdam, The Netherlands.; Department of Public and Occupational Health, Amsterdam UMC, Amsterdam, The Netherlands.; Department of Public Health, Amsterdam Public Health (APH) Research Institute, Academic Medical Center, Amsterdam UMC, Amsterdam, The Netherlands., Ekroos S; Faculty of Medicine, University of Helsinki, Helsinki, Finland., Castrén J; Finnish Red Cross Blood Service (FRCBS), Research and Development, Helsinki, Finland., Arvas M; Finnish Red Cross Blood Service (FRCBS), Research and Development, Helsinki, Finland., van den Hurk K; Donor Studies, Department of Donor Medicine Research, Sanquin Research, Amsterdam, The Netherlands.; Department of Public and Occupational Health, Amsterdam UMC, Amsterdam, The Netherlands.; Department of Public Health, Amsterdam Public Health (APH) Research Institute, Academic Medical Center, Amsterdam UMC, Amsterdam, The Netherlands. |
| المصدر: | Vox sanguinis [Vox Sang] 2024 Jul; Vol. 119 (7), pp. 664-674. Date of Electronic Publication: 2024 Apr 15. |
| نوع المنشور: | Journal Article; Comparative Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: Blackwell Science Country of Publication: England NLM ID: 0413606 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1423-0410 (Electronic) Linking ISSN: 00429007 NLM ISO Abbreviation: Vox Sang Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2001- : Oxford, UK : Blackwell Science Original Publication: Basel : Karger |
| مواضيع طبية MeSH: | Blood Donors* , Ferritins*/blood , Iron*/blood, Humans ; Finland/epidemiology ; Female ; Netherlands/epidemiology ; Middle Aged ; Adult ; Male ; Anemia, Iron-Deficiency/epidemiology ; Anemia, Iron-Deficiency/blood ; Cohort Studies ; Prevalence ; Aged ; Iron Deficiencies |
| مستخلص: | Background and Objectives: Blood donors are at risk of developing iron deficiency (ID) (ferritin <15 μg/L, World Health Organization definition). Blood services implement different strategies to mitigate this risk. Although in Finland risk group-based iron supplementation is in place, no iron supplementation is provided in the Netherlands. We aim to describe differences in ferritin levels and ID prevalence in donor and general populations in these countries. Materials and Methods: Six cohorts, stratified based on sex, and for women age, in the Netherlands and Finland were used to evaluate differences in ferritin levels and ID between donor populations (Donor InSight-III and FinDonor 10,000) and general populations (Prevention of Renal and Vascular End-Stage Disease [PREVEND], FinRisk 1997 and Health 2000) and newly registered Dutch donors. Multivariable logistic regression was used to quantify associations of various explanatory factors with ID. Results: In total, 13,443 Dutch and 13,933 Finnish subjects were included. Donors, except for women aged ≤50 years old in Finland, had lower median ferritin levels compared with the general population and new donors. Dutch regular blood donors had higher or similar prevalence of ID as compared with the Dutch general population, including new donors. In contrast, Finnish donors showed similar prevalence of ID compared with the general population, except for a markedly lower prevalence in ≤50-year-old women who routinely receive iron supplements when donating. Conclusion: Iron status in blood donors differs from that in the general population. The Finnish blood service donor management policy, for example, iron supplementation for risk groups, seemingly protects young female blood donors from developing ID. (© 2024 The Authors. Vox Sanguinis published by John Wiley & Sons Ltd on behalf of International Society of Blood Transfusion.) |
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| معلومات مُعتمدة: | PPOC19-02 Sanquin's Research Programming Committee; Finnish Red Cross Blood Service |
| فهرسة مساهمة: | Keywords: blood donation; cross‐cohort comparison; ferritin; iron deficiency; iron supplementation |
| المشرفين على المادة: | 9007-73-2 (Ferritins) E1UOL152H7 (Iron) |
| تواريخ الأحداث: | Date Created: 20240416 Date Completed: 20240710 Latest Revision: 20240710 |
| رمز التحديث: | 20240710 |
| DOI: | 10.1111/vox.13639 |
| PMID: | 38622934 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1423-0410 |
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| DOI: | 10.1111/vox.13639 |