دورية أكاديمية

From intestinal failure to transplantation: Review on the current need for transplant indications under multidisciplinary transplant programs worldwide.

التفاصيل البيبلوغرافية
العنوان: From intestinal failure to transplantation: Review on the current need for transplant indications under multidisciplinary transplant programs worldwide.
المؤلفون: Raghu VK; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Rumbo C; Unidad de Soporte Nutricional, Rehabilitación y Trasplante Intestinal Hospital Universitario Fundación Favaloro, Buenos Aires, Argentina., Horslen SP; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
المصدر: Pediatric transplantation [Pediatr Transplant] 2024 May; Vol. 28 (3), pp. e14756.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Munksgaard Country of Publication: Denmark NLM ID: 9802574 Publication Model: Print Cited Medium: Internet ISSN: 1399-3046 (Electronic) Linking ISSN: 13973142 NLM ISO Abbreviation: Pediatr Transplant Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Copenhagen ; Malden, MA : Munksgaard, c1997-
مواضيع طبية MeSH: Intestinal Failure* , Transplants* , Intestinal Diseases*/surgery , Short Bowel Syndrome*/surgery, Child ; Infant ; Humans ; Intestines ; Intestine, Small ; Parenteral Nutrition
مستخلص: Introduction: Intestinal failure, defined as the loss of gastrointestinal function to the point where nutrition cannot be maintained by enteral intake alone, presents numerous challenges in children, not least the timing of consideration of intestine transplantation.
Objectives: To describe the evolution of care of infants and children with intestinal failure including parenteral nutrition, intestine transplantation, and contemporary intestinal failure care.
Methods: The review is based on the authors' experience supported by an in-depth review of the published literature.
Results: The history of parenteral nutrition, including out-patient (home) administration, and intestine transplantation are reviewed along with the complications of intestinal failure that may become indications for consideration of intestine transplantation. Current management strategies for children with intestinal failure are discussed along with changes in need for intestine transplantation, recognizing the difficulty in generalizing recommendations due to the high level of heterogeneity of intestinal pathology and residual bowel anatomy and function.
Discussion: Advances in the medical and surgical care of children with intestinal failure have resulted in improved transplant-free survival and a significant fall in demand for transplantation. Despite these improvements a number of children continue to fail rehabilitative care and require intestine transplantation as life-saving therapy or when the burden on ongoing parenteral nutrition becomes too great to bear.
(© 2024 The Authors. Pediatric Transplantation published by Wiley Periodicals LLC.)
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معلومات مُعتمدة: KL2 TR001856 United States TR NCATS NIH HHS
فهرسة مساهمة: Keywords: gastrointestinal; intestinal failure; intestinal rehabilitation; intestinal transplantation; liver/intestine transplant; pediatric transplantation
تواريخ الأحداث: Date Created: 20240416 Date Completed: 20240417 Latest Revision: 20240525
رمز التحديث: 20240525
مُعرف محوري في PubMed: PMC11115375
DOI: 10.1111/petr.14756
PMID: 38623905
قاعدة البيانات: MEDLINE
الوصف
تدمد:1399-3046
DOI:10.1111/petr.14756