دورية أكاديمية
أعرض في EDS

Left bundle branch area versus conventional pacing after transcatheter valve implant for aortic stenosis: the LATVIA study.

التفاصيل البيبلوغرافية
العنوان: Left bundle branch area versus conventional pacing after transcatheter valve implant for aortic stenosis: the LATVIA study.
المؤلفون: Dell'Era G; Clinica Cardiologica, Dipartimento Toraco-Cardio-Vascolare, Ospedale Maggiore della Carità, Novara., Baroni M; Cardiologia 3. A. De' Gasperis Cardio Center, ASST GOM Niguarda Hospital., Frontera A; Cardiologia 3. A. De' Gasperis Cardio Center, ASST GOM Niguarda Hospital., Ghiglieno C; Clinica Cardiologica, Dipartimento Toraco-Cardio-Vascolare, Ospedale Maggiore della Carità, Novara., Carbonaro M; Cardiologia 3. A. De' Gasperis Cardio Center, ASST GOM Niguarda Hospital., Penela D; Humanitas Research Hospital, Rozzano, Milan., Romano C; Università del Piemonte Orientale Amedeo Avogadro, Italy., Giordano F; Cardiologia 3. A. De' Gasperis Cardio Center, ASST GOM Niguarda Hospital., Del Monaco G; Humanitas Research Hospital, Rozzano, Milan., Galimberti P; Humanitas Research Hospital, Rozzano, Milan., Mazzone P; Cardiologia 3. A. De' Gasperis Cardio Center, ASST GOM Niguarda Hospital., Patti G; Clinica Cardiologica, Dipartimento Toraco-Cardio-Vascolare, Ospedale Maggiore della Carità, Novara.; Università del Piemonte Orientale Amedeo Avogadro, Italy.
المصدر: Journal of cardiovascular medicine (Hagerstown, Md.) [J Cardiovasc Med (Hagerstown)] 2024 Jun 01; Vol. 25 (6), pp. 450-456. Date of Electronic Publication: 2024 Apr 01.
نوع المنشور: Journal Article; Multicenter Study; Comparative Study
اللغة: English
بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 101259752 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-2035 (Electronic) Linking ISSN: 15582027 NLM ISO Abbreviation: J Cardiovasc Med (Hagerstown) Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Hagerstown, MD : Lippincott Williams & Wilkins, c2006-
مواضيع طبية MeSH: Aortic Valve Stenosis*/surgery , Aortic Valve Stenosis*/physiopathology , Transcatheter Aortic Valve Replacement*/adverse effects , Atrioventricular Block*/etiology , Atrioventricular Block*/therapy , Atrioventricular Block*/physiopathology , Atrioventricular Block*/diagnosis , Feasibility Studies* , Cardiac Pacing, Artificial*/adverse effects , Cardiac Pacing, Artificial*/methods , Bundle of His*/physiopathology, Humans ; Male ; Female ; Aged, 80 and over ; Aged ; Treatment Outcome ; Time Factors ; Latvia ; Risk Factors ; Aortic Valve/surgery ; Aortic Valve/physiopathology ; Aortic Valve/diagnostic imaging ; Heart Rate
مستخلص: Background: Atrioventricular block (AVB) is a frequent complication in patients undergoing transcatheter aortic valve implantation (TAVI). Right apex ventricular pacing (RVP) represents the standard treatment but may induce cardiomyopathy over the long term. Left bundle branch area pacing (LBBAP) is a promising alternative, minimizing the risk of desynchrony. However, available evidence with LBBAP after TAVI is still low.
Objective: To assess the feasibility and safety of LBBAP for AVB post-TAVI compared with RVP.
Methods: Consecutive patients developing AVB early after TAVI were enrolled between 1 January 2022 and 31 December 2022 at three high-volume hospitals and received LBBAP or RVP. Data on procedure and at short-term follow-up (at least 3 months) were collected.
Results: A total of 38 patients (61% men, mean age 83 ± 6 years) were included; 20 patients (53%) received LBBAP. Procedural success was obtained in all patients according to chosen pacing strategy. Electrical pacing performance at implant and after a mean follow-up of 4.2 ± 2.8 months was clinically equivalent for both pacing modalities. In the LBBAP group, procedural time was longer (70 ± 17 versus 58 ± 15 min in the RVP group, P  = 0.02) and paced QRS was shorter (120 ± 19 versus 155 ± 12 ms at implant, P  < 0.001; 119 ± 18 versus 157 ± 9 ms at follow-up, P  < 0.001). Complication rates did not differ between the two groups.
Conclusion: In patients with AVB after TAVI, LBBAP is feasible and safe, resulting in a narrow QRS duration, either acutely and during the follow-up, compared with RVP. Further studies are needed to evaluate if LBBAP reduces pacing-induced cardiomyopathy in this clinical setting.
(Copyright © 2024 Italian Federation of Cardiology - I.F.C. All rights reserved.)
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تواريخ الأحداث: Date Created: 20240416 Date Completed: 20240531 Latest Revision: 20240628
رمز التحديث: 20240628
DOI: 10.2459/JCM.0000000000001619
PMID: 38625833
قاعدة البيانات: MEDLINE
الوصف
تدمد:1558-2035
DOI:10.2459/JCM.0000000000001619